Design, Synthesis, In Vitro and In Vivo Characterization of Selective NKCC1 Inhibitors for the Treatment of Core Symptoms in Down Syndrome

por Borgogno, Marco, Savardi, Annalisa, Manigrasso, Jacopo, Turci, Alessandra, Portioli, Corinne, Ottonello, Giuliana, Bertozzi, Sine Mandrup, Armirotti, Andrea, Contestabile, Andrea, Cancedda, Laura, De Vivo, Marco
Publicado 2021

Discovery of a Small Molecule Drug Candidate for Selective NKCC1 Inhibition in Brain Disorders

por Savardi, Annalisa, Borgogno, Marco, Narducci, Roberto, La Sala, Giuseppina, Ortega, Jose Antonio, Summa, Maria, Armirotti, Andrea, Bertorelli, Rosalia, Contestabile, Andrea, De Vivo, Marco, Cancedda, Laura
Publicado 2020

Novel, Potent, and Druglike Tetrahydroquinazoline Inhibitor That Is Highly Selective for Human Topoisomerase II α over β

por Ortega, Jose Antonio, Arencibia, Jose M., Minniti, Elirosa, Byl, Jo Ann W., Franco-Ulloa, Sebastian, Borgogno, Marco, Genna, Vito, Summa, Maria, Bertozzi, Sine Mandrup, Bertorelli, Rosalia, Armirotti, Andrea, Minarini, Anna, Sissi, Claudia, Osheroff, Neil, De Vivo, Marco
Publicado 2020