X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus

por Bornholdt, Zachary A., Prasad, B. V. Venkataram
Publicado 2008

A Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral Entry

por Fels, J. Maximilian, Spence, Jennifer S., Bortz, Robert H., Bornholdt, Zachary A., Chandran, Kartik
Publicado 2019

133 Structural basis for ebolavirus matrix assembly and budding; protein plasticity allows multiple functions

por Bornholdt, Zachary, Noda, Takeshi, Abelson, Dafna, Halfmann, Peter, Wood, Malcolm, Kawaoa, Yoshihiro, Saphire, Erica Ollmann
Publicado 2014

Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies

por Bornholdt, Zachary A., Ndungo, Esther, Fusco, Marnie L., Bale, Shridhar, Flyak, Andrew I., Crowe, James E., Chandran, Kartik, Saphire, Erica Ollmann
Publicado 2016

Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers

por Wan, William, Clarke, Mairi, Norris, Michael J, Kolesnikova, Larissa, Koehler, Alexander, Bornholdt, Zachary A, Becker, Stephan, Saphire, Erica Ollmann, Briggs, John AG
Publicado 2020

The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold

por Zhang, Adrianna P. P., Bornholdt, Zachary A., Liu, Tong, Abelson, Dafna M., Lee, David E., Li, Sheng, Woods, Virgil L., Saphire, Erica Ollmann
Publicado 2012

Correction: The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold

por Zhang, Adrianna P. P., Bornholdt, Zachary A., Liu, Tong, Abelson, Dafna M., Lee, David E., Li, Sheng, Woods, Virgil L., Saphire, Erica Ollmann
Publicado 2013

Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism

por Bale, Shridhar, Julien, Jean-Philippe, Bornholdt, Zachary A., Kimberlin, Christopher R., Halfmann, Peter, Zandonatti, Michelle A., Kunert, John, Kroon, Gerard J. A., Kawaoka, Yoshihiro, MacRae, Ian J., Wilson, Ian A., Saphire, Erica Ollmann
Publicado 2012

Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment

por Cross, Robert W., Bornholdt, Zachary A., Prasad, Abhishek N., Geisbert, Joan B., Borisevich, Viktoriya, Agans, Krystle N., Deer, Daniel J., Melody, Kevin, Fenton, Karla A., Feldmann, Heinz, Sprecher, Armand, Zeitlin, Larry, Geisbert, Thomas W.
Publicado 2020

Structure and Characterization of Crimean-Congo Hemorrhagic Fever Virus GP38

por Mishra, Akaash K., Moyer, Crystal L., Abelson, Dafna M., Deer, Daniel J., El Omari, Kamel, Duman, Ramona, Lobel, Leslie, Lutwama, Julius J., Dye, John M., Wagner, Armin, Chandran, Kartik, Cross, Robert W., Geisbert, Thomas W., Zeitlin, Larry, Bornholdt, Zachary A., McLellan, Jason S.
Publicado 2020

Passive immunization with an extended half-life monoclonal antibody protects Rhesus macaques against aerosolized ricin toxin

por Roy, Chad J., Van Slyke, Greta, Ehrbar, Dylan, Bornholdt, Zachary A., Brennan, Miles B., Campbell, Lioudmila, Chen, Michelle, Kim, Do, Mlakar, Neil, Whaley, Kevin J., Froude, Jeffrey W., Torres-Velez, Fernando J, Vitetta, Ellen, Didier, Peter J., Doyle-Meyers, Lara, Zeitlin, Larry, Mantis, Nicholas J.
Publicado 2020

Combination therapy protects macaques against advanced Marburg virus disease

por Cross, Robert W., Bornholdt, Zachary A., Prasad, Abhishek N., Borisevich, Viktoriya, Agans, Krystle N., Deer, Daniel J., Abelson, Dafna M., Kim, Do H., Shestowsky, William S., Campbell, Lioudmila A., Bunyan, Elaine, Geisbert, Joan B., Fenton, Karla A., Zeitlin, Larry, Porter, Danielle P., Geisbert, Thomas W.
Publicado 2021

Reversion of Ebolavirus Disease from a Single Intramuscular Injection of a Pan-Ebolavirus Immunotherapeutic

por Kuang, Erin, Cross, Robert W., McCavitt-Malvido, Maria, Abelson, Dafna M., Borisevich, Viktoriya, Stuart, Lauren, Agans, Krystle N., Mlakar, Neil, Marimuthu, Arumugapradeep, Deer, Daniel J., Shestowsky, William S., Kim, Do, Geisbert, Joan B., Zeitlin, Larry, Moyer, Crystal L., Roy, Chad J., Geisbert, Thomas W., Bornholdt, Zachary A.
Publicado 2022

Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine

por Wec, Anna Z., Haslwanter, Denise, Abdiche, Yasmina N., Shehata, Laila, Pedreño-Lopez, Nuria, Moyer, Crystal L., Bornholdt, Zachary A., Lilov, Asparouh, Nett, Juergen H., Jangra, Rohit K., Brown, Michael, Watkins, David I., Ahlm, Clas, Forsell, Mattias N., Rey, Félix A., Barba-Spaeth, Giovanna, Chandran, Kartik, Walker, Laura M.
Publicado 2020

Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein

por Doyle, Michael P., Kose, Nurgun, Borisevich, Viktoriya, Binshtein, Elad, Amaya, Moushimi, Nagel, Marcus, Annand, Edward J., Armstrong, Erica, Bombardi, Robin, Dong, Jinhui, Schey, Kevin L., Broder, Christopher C., Zeitlin, Larry, Kuang, Erin A., Bornholdt, Zachary A., West, Brandyn R., Geisbert, Thomas W., Cross, Robert W., Crowe, James E.
Publicado 2021

Combination therapy with remdesivir and monoclonal antibodies protects nonhuman primates against advanced Sudan virus disease

por Cross, Robert W., Bornholdt, Zachary A., Prasad, Abhishek N., Woolsey, Courtney, Borisevich, Viktoriya, Agans, Krystle N., Deer, Daniel J., Abelson, Dafna M., Kim, Do H., Shestowsky, William S., Campbell, Lioudmila A., Bunyan, Elaine, Geisbert, Joan B., Dobias, Natalie S., Fenton, Karla A., Porter, Danielle P., Zeitlin, Larry, Geisbert, Thomas W.
Publicado 2022

Therapy for Argentine hemorrhagic fever in nonhuman primates with a humanized monoclonal antibody

por Zeitlin, Larry, Cross, Robert W., Geisbert, Joan B., Borisevich, Viktoriya, Agans, Krystle N., Prasad, Abhishek N., Enterlein, Sven, Aman, M. Javad, Bornholdt, Zachary A., Brennan, Miles B., Campbell, Lioudmila, Kim, Do, Mlakar, Neil, Moyer, Crystal L., Pauly, Michael H., Shestowsky, William, Whaley, Kevin J., Fenton, Karla A., Geisbert, Thomas W.
Publicado 2021