Targeted editing of the PSIP1 gene encoding LEDGF/p75 protects cells against HIV infection

por Lampi, Yulia, Van Looveren, Dominique, Vranckx, Lenard S., Thiry, Irina, Bornschein, Simon, Debyser, Zeger, Gijsbers, Rik
Publicado 2019

Gain-of-function mutation in IFIH1 can cause both aicardi-goutières syndrome and systemic lupus erythematosus with IgA-deficiency

por Van Eyck, Lien, De Somer, Lien, Pombal, Diana, Bornschein, Simon, de Zegher, Francis, Liston, Adrian, Wouters, Carine
Publicado 2014

Malt1 self‐cleavage is critical for regulatory T cell homeostasis and anti‐tumor immunity in mice

por Baens, Mathijs, Stirparo, Rocco, Lampi, Youlia, Verbeke, Delphine, Vandepoel, Roel, Cools, Jan, Marynen, Peter, de Bock, Charles E., Bornschein, Simon
Publicado 2018

The Long Non-coding RNA Flatr Anticipates Foxp3 Expression in Regulatory T Cells

por Brajic, Aleksandra, Franckaert, Dean, Burton, Oliver, Bornschein, Simon, Calvanese, Anna L., Demeyer, Sofie, Cools, Jan, Dooley, James, Schlenner, Susan, Liston, Adrian
Publicado 2018

Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia

por Vanden Bempt, Marlies, Demeyer, Sofie, Broux, Michaël, De Bie, Jolien, Bornschein, Simon, Mentens, Nicole, Vandepoel, Roel, Geerdens, Ellen, Radaelli, Enrico, Bornhauser, Beat C., Kulozik, Andreas E., Meijerink, Jules P., Bourquin, Jean-Pierre, de Bock, Charles E., Cools, Jan
Publicado 2018

The T-cell leukemia associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling

por Girardi, Tiziana, Vereecke, Stijn, Sulima, Sergey O., Khan, Yousuf, Fancello, Laura, Briggs, Joseph W., Schwab, Claire, de Beeck, Joyce Op, Verbeeck, Jelle, Royaert, Jonathan, Geerdens, Ellen, Vicente, Carmen, Bornschein, Simon, Harrison, Christine J., Meijerink, Jules P., Cools, Jan, Dinman, Jonathan D., Kampen, Kim R., De Keersmaecker, Kim
Publicado 2017