A conserved histidine modulates HSPB5 structure to trigger chaperone activity in response to stress-related acidosis

por Rajagopal, Ponni, Tse, Eric, Borst, Andrew J, Delbecq, Scott P, Shi, Lei, Southworth, Daniel R, Klevit, Rachel E
Publicado 2015

Vitrification after multiple rounds of sample application and blotting improves particle density on cryo-electron microscopy grids

por Snijder, Joost, Borst, Andrew J., Dosey, Annie, Walls, Alexandra C., Burrell, Anika, Reddy, Vijay S., Kollman, Justin M., Veesler, David
Publicado 2017

Automatically Fixing Errors in Glycoprotein Structures with Rosetta

por Frenz, Brandon, Rämisch, Sebastian, Borst, Andrew J., Walls, Alexandra C., Adolf-Bryfogle, Jared, Schief, William R., Veesler, David, DiMaio, Frank
Publicado 2019

Spatial subcellular organelle networks in single cells

por Venkatesan, Mythreye, Zhang, Nicholas, Marteau, Benoit, Yajima, Yukina, De Zarate Garcia, Nerea Ortiz, Fang, Zhou, Hu, Thomas, Cai, Shuangyi, Ford, Adam, Olszewski, Harrison, Borst, Andrew, Coskun, Ahmet F.
Publicado 2023

Design of Diverse Asymmetric Pockets in De Novo Homo-oligomeric Proteins

por Gerben, Stacey R, Borst, Andrew J, Hicks, Derrick R, Moczygemba, Isabelle, Feldman, David, Coventry, Brian, Yang, Wei, Bera, Asim K., Miranda, Marcos, Kang, Alex, Nguyen, Hannah, Baker, David
Publicado 2023

Fast and versatile sequence-independent protein docking for nanomaterials design using RPXDock

por Sheffler, William, Yang, Erin C., Dowling, Quinton, Hsia, Yang, Fries, Chelsea N., Stanislaw, Jenna, Langowski, Mark D., Brandys, Marisa, Li, Zhe, Skotheim, Rebecca, Borst, Andrew J., Khmelinskaia, Alena, King, Neil P., Baker, David
Publicado 2023

Precisely patterned nanofibres made from extendable protein multiplexes

por Bethel, Neville P., Borst, Andrew J., Parmeggiani, Fabio, Bick, Matthew J., Brunette, TJ, Nguyen, Hannah, Kang, Alex, Bera, Asim K., Carter, Lauren, Miranda, Marcos C., Kibler, Ryan D., Lamb, Mila, Li, Xinting, Sankaran, Banumathi, Baker, David
Publicado 2023

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core

por Borst, Andrew J, Weidle, Connor E, Gray, Matthew D, Frenz, Brandon, Snijder, Joost, Joyce, M Gordon, Georgiev, Ivelin S, Stewart-Jones, Guillaume BE, Kwong, Peter D, McGuire, Andrew T, DiMaio, Frank, Stamatatos, Leonidas, Pancera, Marie, Veesler, David
Publicado 2018

Overcoming Steric Restrictions of VRC01 HIV-1 Neutralizing Antibodies through Immunization

por Parks, K. Rachael, MacCamy, Anna J., Trichka, Josephine, Gray, Matthew, Weidle, Connor, Borst, Andrew J., Khechaduri, Arineh, Takushi, Brittany, Agrawal, Parul, Guenaga, Javier, Wyatt, Richard T., Coler, Rhea, Seaman, Michael, LaBranche, Celia, Montefiori, David C., Veesler, David, Pancera, Marie, McGuire, Andrew, Stamatatos, Leonidas
Publicado 2019

Structure-based design of stabilized recombinant influenza neuraminidase tetramers

por Ellis, Daniel, Lederhofer, Julia, Acton, Oliver J., Tsybovsky, Yaroslav, Kephart, Sally, Yap, Christina, Gillespie, Rebecca A., Creanga, Adrian, Olshefsky, Audrey, Stephens, Tyler, Pettie, Deleah, Murphy, Michael, Sydeman, Claire, Ahlrichs, Maggie, Chan, Sidney, Borst, Andrew J., Park, Young-Jun, Lee, Kelly K., Graham, Barney S., Veesler, David, King, Neil P., Kanekiyo, Masaru
Publicado 2022

Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge

por Malhi, Harman, Homad, Leah J., Wan, Yu-Hsin, Poudel, Bibhav, Fiala, Brooke, Borst, Andrew J., Wang, Jing Yang, Walkey, Carl, Price, Jason, Wall, Abigail, Singh, Suruchi, Moodie, Zoe, Carter, Lauren, Handa, Simran, Correnti, Colin E., Stoddard, Barry L., Veesler, David, Pancera, Marie, Olson, James, King, Neil P., McGuire, Andrew T.
Publicado 2022

Computational design of non-porous, pH-responsive antibody nanoparticles

por Yang, Erin C., Divine, Robby, Miranda, Marcos C., Borst, Andrew J., Sheffler, Will, Zhang, Jason Z, Decarreau, Justin, Saragovi, Amijai, Abedi, Mohamad, Goldbach, Nicolas, Ahlrichs, Maggie, Dobbins, Craig, Hand, Alexis, Cheng, Suna, Lamb, Mila, Levine, Paul M., Chan, Sidney, Skotheim, Rebecca, Fallas, Jorge, Ueda, George, Lubner, Joshua, Somiya, Masaharu, Khmelinskaia, Alena, King, Neil P., Baker, David
Publicado 2023

Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains

por Wang, Jing Yang (John), Khmelinskaia, Alena, Sheffler, William, Miranda, Marcos C., Antanasijevic, Aleksandar, Borst, Andrew J., Torres, Susana V., Shu, Chelsea, Hsia, Yang, Nattermann, Una, Ellis, Daniel, Walkey, Carl, Ahlrichs, Maggie, Chan, Sidney, Kang, Alex, Nguyen, Hannah, Sydeman, Claire, Sankaran, Banumathi, Wu, Mengyu, Bera, Asim K., Carter, Lauren, Fiala, Brooke, Murphy, Michael, Baker, David, Ward, Andrew B., King, Neil P.
Publicado 2023

De novo design of protein structure and function with RFdiffusion

por Watson, Joseph L., Juergens, David, Bennett, Nathaniel R., Trippe, Brian L., Yim, Jason, Eisenach, Helen E., Ahern, Woody, Borst, Andrew J., Ragotte, Robert J., Milles, Lukas F., Wicky, Basile I. M., Hanikel, Nikita, Pellock, Samuel J., Courbet, Alexis, Sheffler, William, Wang, Jue, Venkatesh, Preetham, Sappington, Isaac, Torres, Susana Vázquez, Lauko, Anna, De Bortoli, Valentin, Mathieu, Emile, Ovchinnikov, Sergey, Barzilay, Regina, Jaakkola, Tommi S., DiMaio, Frank, Baek, Minkyung, Baker, David
Publicado 2023