Epigenetic reprogramming in liver fibrosis and cancer()

por Wilson, Caroline L., Mann, Derek A., Borthwick, Lee A.
Publicado 2017

Implementation of pre-clinical methodologies to study fibrosis and test anti-fibrotic therapy

por Oakley, Fiona, Gee, Lucy M, Sheerin, Neil S, Borthwick, Lee A
Publicado 2019

How Reliable Are Sino-Nasal Cell Lines for Studying the Pathophysiology of Chronic Rhinosinusitis?

por Ball, Stephen L., Suwara, Monika I., Borthwick, Lee A., Wilson, Janet A., Mann, Derek A., Fisher, Andrew J.
Publicado 2015

Quantification of intra-articular fibrosis in patients with stiff knee arthroplasties using metal-reduction MRI

por Attard, Veronica, Li, Cheuk Yin, Self, Alexander, Mann, Derek A., Borthwick, Lee A., O’Connor, Phil, Deehan, David J., Kalson, Nicholas S.
Publicado 2020

Is CFTR-delF508 Really Absent from the Apical Membrane of the Airway Epithelium?

por Borthwick, Lee A., Botha, Phil, Verdon, Bernard, Brodlie, Malcolm J., Gardner, Aaron, Bourn, David, Johnson, Gail E., Gray, Mike A., Fisher, Andrew J.
Publicado 2011

Reduced telomere length is associated with fibrotic joint disease suggesting that impaired telomere repair contributes to joint fibrosis

por Kalson, Nicholas S., Brock, Tim M., Mangino, Massimo, Fabiane, Stella M., Mann, Derek A., Borthwick, Lee A., Deehan, David J., Williams, Frances M. K.
Publicado 2018

Chronic, Active Inflammation in Patients With Failed Total Knee Replacements Undergoing Revision Surgery

por Paish, Hannah L., Baldock, Thomas Edward, Gillespie, Colin S., del Carpio Pons, Alicia, Mann, Derek A., Deehan, David J., Borthwick, Lee A., Kalson, Nicholas S.
Publicado 2019

Fibrosis is a common outcome following total knee arthroplasty

por Abdul, Nicole, Dixon, David, Walker, Andrew, Horabin, Joanna, Smith, Nick, Weir, David J., Brewster, Nigel T., Deehan, David J., Mann, Derek A., Borthwick, Lee A.
Publicado 2015

Role of Interaction and Nucleoside Diphosphate Kinase B in Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Function by cAMP-Dependent Protein Kinase A

por Borthwick, Lee A., Kerbiriou, Mathieu, Taylor, Christopher J., Cozza, Giorgio, Lascu, Ioan, Postel, Edith H., Cassidy, Diane, Trouvé, Pascal, Mehta, Anil, Robson, Louise, Muimo, Richmond
Publicado 2016

Altered Differentiation and Inflammation Profiles Contribute to Enhanced Innate Responses in Severe COPD Epithelium to Rhinovirus Infection

por Guo-Parke, Hong, Linden, Dermot, Mousnier, Aurelie, Scott, Ian C., Killick, Helen, Borthwick, Lee A., Fisher, Andrew J., Weldon, Sinéad, Taggart, Clifford C., Kidney, Joseph C.
Publicado 2022

Role of Arginase 1 from Myeloid Cells in Th2-Dominated Lung Inflammation

por Barron, Luke, Smith, Amber M., El Kasmi, Karim C., Qualls, Joseph E., Huang, Xiaozhu, Cheever, Allen, Borthwick, Lee A., Wilson, Mark S., Murray, Peter J., Wynn, Thomas A.
Publicado 2013

Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis

por Borthwick, Lee A., Barron, Luke, Hart, Kevin M., Vannella, Kevin M., Thompson, Robert W., Oland, Sandra, Cheever, Allen, Sciurba, Joshua, Ramalingam, Thirumalai R., Fisher, Andrew J., Wynn, Thomas A.
Publicado 2015

A potential mode of action for Anakinra in patients with arthrofibrosis following total knee arthroplasty

por Dixon, David, Coates, Jonathon, del Carpio Pons, Alicia, Horabin, Joanna, Walker, Andrew, Abdul, Nicole, Kalson, Nicholas S., Brewster, Nigel T., Weir, David J., Deehan, David J., Mann, Derek A., Borthwick, Lee A.
Publicado 2015

Renal injury and hepatic effects from the methylimidazolium ionic liquid M8OI in mouse

por Leitch, Alistair C., Abdelghany, Tarek M., Charlton, Alex, Grigalyte, Justina, Oakley, Fiona, Borthwick, Lee A., Reed, Lee, Knox, Amber, Reilly, William J., Agius, Loranne, Blain, Peter G., Wright, Matthew C.
Publicado 2020

Incomplete Deletion of IL-4Rα by LysM(Cre) Reveals Distinct Subsets of M2 Macrophages Controlling Inflammation and Fibrosis in Chronic Schistosomiasis

por Vannella, Kevin M., Barron, Luke, Borthwick, Lee A., Kindrachuk, Kristen N., Narasimhan, Prakash Babu, Hart, Kevin M., Thompson, Robert W., White, Sandra, Cheever, Allen W., Ramalingam, Thirumalai R., Wynn, Thomas A.
Publicado 2014

The role of interleukin-1β as a predictive biomarker and potential therapeutic target during clinical ex vivo lung perfusion

por Andreasson, Anders S.I., Borthwick, Lee A., Gillespie, Colin, Jiwa, Kasim, Scott, Jonathan, Henderson, Paul, Mayes, Jonny, Romano, Rosalba, Roman, Marius, Ali, Simi, Fildes, James E., Marczin, Nandor, Dark, John H., Fisher, Andrew J.
Publicado 2017

Fibroblasts Promote Inflammation and Pain via IL-1α Induction of the Monocyte Chemoattractant Chemokine (C-C Motif) Ligand 2

por Paish, Hannah L., Kalson, Nicholas S., Smith, Graham R., del Carpio Pons, Alicia, Baldock, Thomas E., Smith, Nicholas, Swist-Szulik, Katarzyna, Weir, David J., Bardgett, Michelle, Deehan, David J., Mann, Derek A., Borthwick, Lee A.
Publicado 2018

Mechanistic differences between phenotypes of chronic lung allograft dysfunction after lung transplantation

por Suwara, Monika I, Vanaudenaerde, Bart M, Verleden, Stijn E, Vos, Robin, Green, Nicola J, Ward, Chris, Borthwick, Lee A, Vandermeulen, Elly, Lordan, Jim, Van Raemdonck, Dirk E, Corris, Paul A, Verleden, Geert M, Fisher, Andrew J
Publicado 2014

Profiling inflammation and tissue injury markers in perfusate and bronchoalveolar lavage fluid during human ex vivo lung perfusion

por Andreasson, Anders S.I., Karamanou, Danai M., Gillespie, Colin S., Özalp, Faruk, Butt, Tanveer, Hill, Paul, Jiwa, Kasim, Walden, Hannah R., Green, Nicola J., Borthwick, Lee A., Clark, Stephen C., Pauli, Henning, Gould, Kate F., Corris, Paul A., Ali, Simi, Dark, John H., Fisher, Andrew J.
Publicado 2017

Pellino-1 Regulates the Responses of the Airway to Viral Infection

por Marsh, Elizabeth K., Prestwich, Elizabeth C., Williams, Lynne, Hart, Amber R., Muir, Clare F., Parker, Lisa C., Jonker, Marnix R., Heijink, Irene H., Timens, Wim, Fife, Mark, Hussell, Tracy, Hershenson, Marc B., Bentley, J. Kelley, Sun, Shao-Cong, Barksby, Ben S., Borthwick, Lee A., Stewart, James P., Sabroe, Ian, Dockrell, David H., Marriott, Helen M.
Publicado 2020