Increased Expression of Alpha-, Beta-, and Gamma-Synucleins in Brainstem Regions of a Non-Human Primate Model of Parkinson’s Disease

por Duperrier, Sandra, Bortolozzi, Analia, Sgambato, Véronique
Publicado 2022

Intracerebral administration of a modified antisense oligonucleotide targeting the dopamine system in a mouse model of Parkinson’s disease

por Pavia-Collado, Rubén, Miquel-Rio, Lluis, Campa, Leticia, Bortolozzi, Analia
Publicado 2022

The Role of α-Synuclein in the Regulation of Serotonin System: Physiological and Pathological Features

por Miquel-Rio, Lluis, Sarriés-Serrano, Unai, Pavia-Collado, Rubén, Meana, J Javier, Bortolozzi, Analia
Publicado 2023

Functional Rescue of Dopaminergic Neuron Loss in Parkinson's Disease Mice After Transplantation of Hematopoietic Stem and Progenitor Cells

por Altarche-Xifro, Wassim, di Vicino, Umberto, Muñoz-Martin, Maria Isabel, Bortolozzi, Analía, Bové, Jordi, Vila, Miquel, Cosma, Maria Pia
Publicado 2016

Up and Down γ-Synuclein Transcription in Dopamine Neurons Translates into Changes in Dopamine Neurotransmission and Behavioral Performance in Mice

por Pavia-Collado, Rubén, Rodríguez-Aller, Raquel, Alarcón-Arís, Diana, Miquel-Rio, Lluís, Ruiz-Bronchal, Esther, Paz, Verónica, Campa, Leticia, Galofré, Mireia, Sgambato, Véronique, Bortolozzi, Analia
Publicado 2022

mTOR Knockdown in the Infralimbic Cortex Evokes A Depressive-like State in Mouse

por Garro-Martínez, Emilio, Fullana, Maria Neus, Florensa-Zanuy, Eva, Senserrich, Julia, Paz, Verónica, Ruiz-Bronchal, Esther, Adell, Albert, Castro, Elena, Díaz, Álvaro, Pazos, Ángel, Bortolozzi, Analía, Pilar-Cuéllar, Fuencisla
Publicado 2021

Intracerebral Administration of a Ligand-ASO Conjugate Selectively Reduces α-Synuclein Accumulation in Monoamine Neurons of Double Mutant Human A30P*A53T*α-Synuclein Transgenic Mic...

por Pavia-Collado, Rubén, Cóppola-Segovia, Valentín, Miquel-Rio, Lluís, Alarcón-Aris, Diana, Rodríguez-Aller, Raquel, Torres-López, María, Paz, Verónica, Ruiz-Bronchal, Esther, Campa, Leticia, Artigas, Francesc, Montefeltro, Andrés, Revilla, Raquel, Bortolozzi, Analia
Publicado 2021

Human α-synuclein overexpression in mouse serotonin neurons triggers a depressive-like phenotype. Rescue by oligonucleotide therapy

por Miquel-Rio, Lluis, Alarcón-Arís, Diana, Torres-López, María, Cóppola-Segovia, Valentín, Pavia-Collado, Rubén, Paz, Verónica, Ruiz-Bronchal, Esther, Campa, Leticia, Casal, Carme, Montefeltro, Andrés, Vila, Miquel, Artigas, Francesc, Revilla, Raquel, Bortolozzi, Analia
Publicado 2022

Brain tyrosinase overexpression implicates age-dependent neuromelanin production in Parkinson’s disease pathogenesis

por Carballo-Carbajal, Iria, Laguna, Ariadna, Romero-Giménez, Jordi, Cuadros, Thais, Bové, Jordi, Martinez-Vicente, Marta, Parent, Annabelle, Gonzalez-Sepulveda, Marta, Peñuelas, Núria, Torra, Albert, Rodríguez-Galván, Beatriz, Ballabio, Andrea, Hasegawa, Takafumi, Bortolozzi, Analía, Gelpi, Ellen, Vila, Miquel
Publicado 2019

Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys

por Alarcón-Arís, Diana, Pavia-Collado, Rubén, Miquel-Rio, Lluis, Coppola-Segovia, Valentín, Ferrés-Coy, Albert, Ruiz-Bronchal, Esther, Galofré, Mireia, Paz, Verónica, Campa, Leticia, Revilla, Raquel, Montefeltro, Andrés, Kordower, Jeffrey H., Vila, Miquel, Artigas, Francesc, Bortolozzi, Analia
Publicado 2020

Lipid nanoparticles for antisense oligonucleotide gene interference into brain border-associated macrophages

por Calero, Macarena, Moleiro, Lara H., Sayd, Aline, Dorca, Yeray, Miquel-Rio, Lluis, Paz, Verónica, Robledo-Montaña, Javier, Enciso, Eduardo, Acción, Fernando, Herráez-Aguilar, Diego, Hellweg, Thomas, Sánchez, Luis, Bortolozzi, Analía, Leza, Juan C., García-Bueno, Borja, Monroy, Francisco
Publicado 2022

iPSC‐based modeling of THD recapitulates disease phenotypes and reveals neuronal malformation

por Tristán‐Noguero, Alba, Fernández‐Carasa, Irene, Calatayud, Carles, Bermejo‐Casadesús, Cristina, Pons‐Espinal, Meritxell, Colini Baldeschi, Arianna, Campa, Leticia, Artigas, Francesc, Bortolozzi, Analia, Domingo‐Jiménez, Rosario, Ibáñez, Salvador, Pineda, Mercè, Artuch, Rafael, Raya, Ángel, García‐Cazorla, Àngels, Consiglio, Antonella
Publicado 2023

Thalamic Foxp2 regulates output connectivity and sensory-motor impairments in a model of Huntington’s Disease

por Rodríguez-Urgellés, Ened, Casas-Torremocha, Diana, Sancho-Balsells, Anna, Ballasch, Iván, García-García, Esther, Miquel-Rio, Lluis, Manasanch, Arnau, del Castillo, Ignacio, Chen, Wanqi, Pupak, Anika, Brito, Veronica, Tornero, Daniel, Rodríguez, Manuel J., Bortolozzi, Analia, Sanchez-Vives, Maria V., Giralt, Albert, Alberch, Jordi
Publicado 2023

Behavioural traits propagate across generations via segregated iterative-somatic and gametic epigenetic mechanisms

por Mitchell, Emma, Klein, Shifra L., Argyropoulos, Kimon V., Sharma, Ali, Chan, Robin B., Toth, Judit Gal, Barboza, Luendreo, Bavley, Charlotte, Bortolozzi, Analia, Chen, Qiuying, Liu, Bingfang, Ingenito, Joanne, Mark, Willie, Dudakov, Jarrod, Gross, Steven, Di Paolo, Gilbert, Artigas, Francesc, van den Brink, Marcel, Toth, Miklos
Publicado 2016