Inhibitory receptors for HLA class I as immune checkpoints for natural killer cell-mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy

por Beelen, Nicky A., Ehlers, Femke A. I., Bos, Gerard M. J., Wieten, Lotte
Publicado 2022

Tuning Natural Killer Cell Anti-multiple Myeloma Reactivity by Targeting Inhibitory Signaling via KIR and NKG2A

por Mahaweni, Niken M., Ehlers, Femke A. I., Bos, Gerard M. J., Wieten, Lotte
Publicado 2018

The Perception of Shared Decision-Making in Hematology by Patients and Physicians Seems Satisfactory, but Important Steps are Still Ahead of Us

por Geerts, Paulus A.F., van der Weijden, Trudy, Moser, Albine, Bos, Gerard M.J.
Publicado 2020

Daratumumab augments alloreactive natural killer cell cytotoxicity towards CD38+ multiple myeloma cell lines in a biochemical context mimicking tumour microenvironment conditions

por Mahaweni, Niken M., Bos, Gerard M. J., Mitsiades, Constantine S., Tilanus, Marcel G. J., Wieten, Lotte
Publicado 2018

Chimeric antigen receptor natural killer (CAR-NK) cell design and engineering for cancer therapy

por Gong, Ying, Klein Wolterink, Roel G. J., Wang, Jianxiang, Bos, Gerard M. J., Germeraad, Wilfred T. V.
Publicado 2021

Activated Natural Killer Cells Withstand the Relatively Low Glucose Concentrations Found in the Bone Marrow of Multiple Myeloma Patients

por Ehlers, Femke A. I., Mahaweni, Niken M., Olieslagers, Timo I., Bos, Gerard M. J., Wieten, Lotte
Publicado 2021

Pathogen-Associated Molecular Patterns Induced Crosstalk between Dendritic Cells, T Helper Cells, and Natural Killer Helper Cells Can Improve Dendritic Cell Vaccination

por Oth, Tammy, Vanderlocht, Joris, Van Elssen, Catharina H. M. J., Bos, Gerard M. J., Germeraad, Wilfred T. V.
Publicado 2016

Bone marrow produces sufficient alloreactive natural killer (NK) cells in vivo to cure mice from subcutaneously and intravascularly injected 4T1 breast cancer

por van Gelder, Michel, Vanclée, Ariane, van Elssen, Catharina H. M. J., Hupperets, Pierre, Wieten, Lotte, Bos, Gerard M.
Publicado 2016

The Effect of Vitamin C (Ascorbic Acid) in the Treatment of Patients with Cancer: A Systematic Review

por van Gorkom, Gwendolyn N.Y., Lookermans, Eline L., Van Elssen, Catharina H.M.J., Bos, Gerard M.J.
Publicado 2019

Ascorbic acid serum levels are reduced in patients with hematological malignancies

por Huijskens, Mirelle J.A.J., Wodzig, Will K.W.H., Walczak, Mateusz, Germeraad, Wilfred T.V., Bos, Gerard M.J.
Publicado 2016

Pathogen recognition by NK cells amplifies the pro-inflammatory cytokine production of monocyte-derived DC via IFN-γ

por Oth, Tammy, Habets, Thomas H. P. M., Germeraad, Wilfred T. V., Zonneveld, Marijke I., Bos, Gerard M. J., Vanderlocht, Joris
Publicado 2018

Exploring the potential of combining IL-2-activated NK cells with an anti-PDL1 monoclonal antibody to target multiple myeloma-associated macrophages

por Ehlers, Femke A. I., Mahaweni, Niken M., van de Waterweg Berends, Annet, Saya, Thara, Bos, Gerard M. J., Wieten, Lotte
Publicado 2023

Medical Students Perceive Better Group Learning Processes when Large Classes Are Made to Seem Small

por Hommes, Juliette, Arah, Onyebuchi A., de Grave, Willem, Schuwirth, Lambert W. T., Scherpbier, Albert J. J. A., Bos, Gerard M. J.
Publicado 2014

Rosuvastatin Enhances VSV-G Lentiviral Transduction of NK Cells via Upregulation of the Low-Density Lipoprotein Receptor

por Gong, Ying, Klein Wolterink, Roel G.J., Janssen, Ian, Groot, Arjan J., Bos, Gerard M.J., Germeraad, Wilfred T.V.
Publicado 2020

Antibody-dependent cellular cytotoxicity-inducing antibodies enhance the natural killer cell anti-cancer response against patient-derived pancreatic cancer organoids

por Beelen, Nicky A., Aberle, Merel R., Bruno, Virginia, Olde Damink, Steven W. M., Bos, Gerard M. J., Rensen, Sander S., Wieten, Lotte
Publicado 2023

Monitoring the Initiation and Kinetics of Human Dendritic Cell-Induced Polarization of Autologous Naive CD4(+) T Cells

por Oth, Tammy, Schnijderberg, Melanie C. A., Senden-Gijsbers, Birgit L. M. G., Germeraad, Wilfred T. V., Bos, Gerard M. J., Vanderlocht, Joris
Publicado 2014

Hypoxia Induced Impairment of NK Cell Cytotoxicity against Multiple Myeloma Can Be Overcome by IL-2 Activation of the NK Cells

por Sarkar, Subhashis, Germeraad, Wilfred T. V., Rouschop, Kasper M. A., Steeghs, Elisabeth M. P., van Gelder, Michel, Bos, Gerard M. J., Wieten, Lotte
Publicado 2013

NKG2A Expression Is Not per se Detrimental for the Anti-Multiple Myeloma Activity of Activated Natural Killer Cells in an In Vitro System Mimicking the Tumor Microenvironment

por Mahaweni, Niken M., Ehlers, Femke A. I., Sarkar, Subhashis, Janssen, Johanna W. H., Tilanus, Marcel G. J., Bos, Gerard M. J., Wieten, Lotte
Publicado 2018

Polymorphic differences within HLA‐C alleles contribute to alternatively spliced transcripts lacking exon 5

por Ehlers, Femke A. I., Olieslagers, Timo I., Groeneweg, Mathijs, Bos, Gerard M. J., Tilanus, Marcel G. J., Voorter, Christina E. M., Wieten, Lotte
Publicado 2022

Influence of Vitamin C on Lymphocytes: An Overview

por van Gorkom, Gwendolyn N. Y., Klein Wolterink, Roel G. J., Van Elssen, Catharina H. M. J., Wieten, Lotte, Germeraad, Wilfred T. V., Bos, Gerard M. J.
Publicado 2018