Oncogenic FGFR Fusions Produce Centrosome and Cilia Defects by Ectopic Signaling

por Nita, Alexandru, Abraham, Sara P., Krejci, Pavel, Bosakova, Michaela
Publicado 2021

MORN5 Expression during Craniofacial Development and Its Interaction with the BMP and TGFβ Pathways

por Cela, Petra, Hampl, Marek, Fu, Katherine K., Kunova Bosakova, Michaela, Krejci, Pavel, Richman, Joy M., Buchtova, Marcela
Publicado 2016

Colicin F(Y) inhibits pathogenic Yersinia enterocolitica in mice

por Bosák, Juraj, Micenková, Lenka, Hrala, Matěj, Pomorská, Katarína, Kunova Bosakova, Michaela, Krejci, Pavel, Göpfert, Eduard, Faldyna, Martin, Šmajs, David
Publicado 2018

Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480

por Gudernova, Iva, Balek, Lukas, Varecha, Miroslav, Kucerova, Jana Fialova, Kunova Bosakova, Michaela, Fafilek, Bohumil, Palusova, Veronika, Uldrijan, Stjepan, Trantirek, Lukas, Krejci, Pavel
Publicado 2017

Intervertebral disc degeneration is rescued by TGFβ/BMP signaling modulation in an ex vivo filamin B mouse model

por Zieba, Jennifer, Forlenza, Kimberly N., Heard, Kelly, Martin, Jorge H., Bosakova, Michaela, Cohn, Daniel H., Robertson, Stephen P., Krejci, Pavel, Krakow, Deborah
Publicado 2022

Skeletal diseases caused by mutations in PTH1R show aberrant differentiation of skeletal progenitors due to dysregulation of DEPTOR

por Csukasi, Fabiana, Bosakova, Michaela, Barta, Tomas, Martin, Jorge H., Arcedo, Jesus, Barad, Maya, Rico-Llanos, Gustavo A., Zieba, Jennifer, Becerra, Jose, Krejci, Pavel, Duran, Ivan, Krakow, Deborah
Publicado 2023

One reporter for in-cell activity profiling of majority of protein kinase oncogenes

por Gudernova, Iva, Foldynova-Trantirkova, Silvie, Ghannamova, Barbora El, Fafilek, Bohumil, Varecha, Miroslav, Balek, Lukas, Hruba, Eva, Jonatova, Lucie, Jelinkova, Iva, Bosakova, Michaela Kunova, Trantirek, Lukas, Mayer, Jiri, Krejci, Pavel
Publicado 2017

Biallelic mutations in LAMA5 disrupts a skeletal noncanonical focal adhesion pathway and produces a distinct bent bone dysplasia

por Barad, Maya, Csukasi, Fabiana, Bosakova, Michaela, Martin, Jorge H., Zhang, Wenjuan, Paige Taylor, S., Lachman, Ralph S., Zieba, Jennifer, Bamshad, Michael, Nickerson, Deborah, Chong, Jessica X., Cohn, Daniel H., Krejci, Pavel, Krakow, Deborah, Duran, Ivan
Publicado 2020

Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling

por Bosakova, Michaela, Abraham, Sara P, Nita, Alexandru, Hruba, Eva, Buchtova, Marcela, Taylor, S Paige, Duran, Ivan, Martin, Jorge, Svozilova, Katerina, Barta, Tomas, Varecha, Miroslav, Balek, Lukas, Kohoutek, Jiri, Radaszkiewicz, Tomasz, Pusapati, Ganesh V, Bryja, Vitezslav, Rush, Eric T, Thiffault, Isabelle, Nickerson, Deborah A, Bamshad, Michael J, Rohatgi, Rajat, Cohn, Daniel H, Krakow, Deborah, Krejci, Pavel
Publicado 2020

Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase

por Kunova Bosakova, Michaela, Nita, Alexandru, Gregor, Tomas, Varecha, Miroslav, Gudernova, Iva, Fafilek, Bohumil, Barta, Tomas, Basheer, Neha, Abraham, Sara P., Balek, Lukas, Tomanova, Marketa, Fialova Kucerova, Jana, Bosak, Juraj, Potesil, David, Zieba, Jennifer, Song, Jieun, Konik, Peter, Park, Sohyun, Duran, Ivan, Zdrahal, Zbynek, Smajs, David, Jansen, Gert, Fu, Zheng, Ko, Hyuk Wan, Hampl, Ales, Trantirek, Lukas, Krakow, Deborah, Krejci, Pavel
Publicado 2019