Engineered IgG1-Fc Molecules Define Valency Control of Cell Surface Fcγ Receptor Inhibition and Activation in Endosomes

por Bailey, Elizabeth M., Choudhury, Amit, Vuppula, Harika, Ortiz, Daniel F., Schaeck, John, Manning, Anthony M., Bosques, Carlos J., Hoppe, Adam D.
Publicado 2021

Inhibitory Fc-Gamma IIb Receptor Signaling Induced by Multivalent IgG-Fc Is Dependent on Sialylation

por Beneduce, Christopher, Nguyen, Stephanie, Washburn, Nathaniel, Schaeck, John, Meccariello, Robin, Holte, Kimberly, Ortiz, Daniel, Manning, Anthony M., Bosques, Carlos J., Kurtagic, Elma
Publicado 2023

High-resolution physicochemical characterization of different intravenous immunoglobulin products

por Washburn, Nathaniel, Meccariello, Robin, Hu, Shaohui, Hains, Maurice, Bhatnagar, Naveen, Sarvaiya, Hetal, Kapoor, Bulbul, Schaeck, John, Pino, Ignacio, Manning, Anthony, Lansing, Jonathan C., Bosques, Carlos J.
Publicado 2017

Characterization of Endogenous Human FcγRIII by Mass Spectrometry Reveals Site, Allele and Sequence Specific Glycosylation*

por Washburn, Nathaniel, Meccariello, Robin, Duffner, Jay, Getchell, Kristen, Holte, Kimberly, Prod'homme, Thomas, Srinivasan, Karunya, Prenovitz, Robert, Lansing, Jonathan, Capila, Ishan, Kaundinya, Ganesh, Manning, Anthony M., Bosques, Carlos J.
Publicado 2019