Dual targeting of higher-order DNA structures by azacryptands induces DNA junction-mediated DNA damage in cancer cells

por Zell, Joanna, Duskova, Katerina, Chouh, Leïla, Bossaert, Madeleine, Chéron, Nicolas, Granzhan, Anton, Britton, Sébastien, Monchaud, David
Publicado 2021

Transcription-associated topoisomerase 2α (TOP2A) activity is a major effector of cytotoxicity induced by G-quadruplex ligands

por Bossaert, Madeleine, Pipier, Angélique, Riou, Jean-Francois, Noirot, Céline, Nguyên, Linh-Trang, Serre, Remy-Felix, Bouchez, Olivier, Defrancq, Eric, Calsou, Patrick, Britton, Sébastien, Gomez, Dennis
Publicado 2021

PAXX binding to the NHEJ machinery explains functional redundancy with XLF

por Seif-El-Dahan, Murielle, Kefala-Stavridi, Antonia, Frit, Philippe, Hardwick, Steven W., Chirgadze, Dima Y., Maia De Oliviera, Taiana, Britton, Sébastien, Barboule, Nadia, Bossaert, Madeleine, Pandurangan, Arun Prasad, Meek, Katheryn, Blundell, Tom L., Ropars, Virginie, Calsou, Patrick, Charbonnier, Jean-Baptiste, Chaplin, Amanda K.
Publicado 2023