Immune-Based Approaches for the Treatment of Pediatric Malignancies

por Bosse, Kristopher R., Majzner, Robbie G., Mackall, Crystal L., Maris, John M.
Publicado 2020

Antibody–Drug Conjugate Efficacy in Neuroblastoma: Role of Payload, Resistance Mechanisms, Target Density, and Antibody Internalization

por Buongervino, Samantha, Lane, Maria V., Garrigan, Emily, Zhelev, Doncho V., Dimitrov, Dimiter S., Bosse, Kristopher R.
Publicado 2021

CAMKV Is a Candidate Immunotherapeutic Target in MYCN Amplified Neuroblastoma

por Sussman, Robyn T., Rokita, Jo Lynne, Huang, Kevin, Raman, Pichai, Rathi, Komal S., Martinez, Daniel, Bosse, Kristopher R., Lane, Maria, Hart, Lori S., Bhatti, Tricia, Pawel, Bruce, Maris, John M.
Publicado 2020

BARD1 germline variants induce haploinsufficiency and DNA repair defects in neuroblastoma

por Randall, Michael P., Egolf, Laura E., Vaksman, Zalman, Samanta, Minu, Tsang, Matthew, Groff, David, Evans, J. Perry, Rokita, Jo Lynne, Layeghifard, Mehdi, Shlien, Adam, Maris, John M., Diskin, Sharon J., Bosse, Kristopher R.
Publicado 2023

GPC2 antibody–drug conjugate reprograms the neuroblastoma immune milieu to enhance macrophage-driven therapies

por Pascual-Pasto, Guillem, McIntyre, Brendan, Shraim, Rawan, Buongervino, Samantha N, Erbe, Amy K, Zhelev, Doncho V, Sadirova, Shakhnozakhon, Giudice, Anna M, Martinez, Daniel, Garcia-Gerique, Laura, Dimitrov, Dimiter S, Sondel, Paul M, Bosse, Kristopher R
Publicado 2022

LIN28B promotes neuroblastoma metastasis and regulates PDZ binding kinase

por Chen, Dongdong, Cox, Julie, Annam, Jayabhargav, Weingart, Melanie, Essien, Grace, Rathi, Komal S., Rokita, Jo Lynne, Khurana, Priya, Cuya, Selma M., Bosse, Kristopher R., Pilgrim, Adeiye, Li, Daisy, Shields, Cara, Laur, Oskar, Maris, John M., Schnepp, Robert W.
Publicado 2020

A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope

por Raman, Swetha, Buongervino, Samantha N., Lane, Maria V., Zhelev, Doncho V., Zhu, Zhongyu, Cui, Hong, Martinez, Benjamin, Martinez, Daniel, Wang, Yanping, Upton, Kristen, Patel, Khushbu, Rathi, Komal S., Navia, Carmen T., Harmon, Daniel B., Li, Yimei, Pawel, Bruce, Dimitrov, Dimiter S., Maris, John M., Julien, Jean-Philippe, Bosse, Kristopher R.
Publicado 2021

Epigenetic state determines inflammatory sensing in neuroblastoma

por Wolpaw, Adam J., Grossmann, Liron D., Dessau, Jessica L., Dong, May M., Aaron, Bailey J., Brafford, Patricia A., Volgina, Darya, Pascual-Pasto, Guillem, Rodriguez-Garcia, Alba, Uzun, Yasin, Arsenian-Henriksson, Marie, Powell, Daniel J., Bosse, Kristopher R., Kossenkov, Andrew, Tan, Kai, Hogarty, Michael D., Maris, John M., Dang, Chi V.
Publicado 2022

Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors

por Foster, Jessica B, Griffin, Crystal, Rokita, Jo Lynne, Stern, Allison, Brimley, Cameron, Rathi, Komal, Lane, Maria V, Buongervino, Samantha N, Smith, Tiffany, Madsen, Peter J, Martinez, Daniel, Delaidelli, Alberto, Sorensen, Poul H, Wechsler-Reya, Robert J, Karikó, Katalin, Storm, Phillip B, Barrett, David M, Resnick, Adam C, Maris, John M, Bosse, Kristopher R
Publicado 2022

A MYCN-independent mechanism mediating secretome reprogramming and metastasis in MYCN-amplified neuroblastoma

por Zhang, Hai-Feng, Delaidelli, Alberto, Javed, Sumreen, Turgu, Busra, Morrison, Taylor, Hughes, Christopher S., Yang, Xiaqiu, Pachva, Manideep, Lizardo, Michael M., Singh, Gurdeep, Hoffmann, Jennifer, Huang, Yue Zhou, Patel, Khushbu, Shraim, Rawan, Kung, Sonia H. Y., Morin, Gregg B., Aparicio, Samuel, Martinez, Daniel, Maris, John M., Bosse, Kristopher R., Williams, Karla C., Sorensen, Poul H.
Publicado 2023

Retraction Note: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs

por Yarmarkovich, Mark, Marshall, Quinlen F., Warrington, John M., Premaratne, Rasika, Farrel, Alvin, Groff, David, Li, Wei, di Marco, Moreno, Runbeck, Erin, Truong, Hau, Toor, Jugmohit S., Tripathi, Sarvind, Nguyen, Son, Shen, Helena, Noel, Tiffany, Church, Nicole L., Weiner, Amber, Kendsersky, Nathan, Martinez, Dan, Weisberg, Rebecca, Christie, Molly, Eisenlohr, Laurence, Bosse, Kristopher R., Dimitrov, Dimiter S., Stevanovic, Stefan, Sgourakis, Nikolaos G., Kiefel, Ben R., Maris, John M.
Publicado 2023

Targeting of intracellular oncoproteins with peptide-centric CARs

por Yarmarkovich, Mark, Marshall, Quinlen F., Warrington, John M., Premaratne, Rasika, Farrel, Alvin, Groff, David, Li, Wei, di Marco, Moreno, Runbeck, Erin, Truong, Hau, Toor, Jugmohit S., Tripathi, Sarvind, Nguyen, Son, Shen, Helena, Noel, Tiffany, Church, Nicole L., Weiner, Amber, Kendsersky, Nathan, Martinez, Dan, Weisberg, Rebecca, Christie, Molly, Eisenlohr, Laurence, Bosse, Kristopher R., Dimitrov, Dimiter S., Stevanovic, Stefan, Sgourakis, Nikolaos G., Kiefel, Ben R., Maris, John M.
Publicado 2023

RETRACTED ARTICLE: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs

por Yarmarkovich, Mark, Marshall, Quinlen F., Warrington, John M., Premaratne, Rasika, Farrel, Alvin, Groff, David, Li, Wei, di Marco, Moreno, Runbeck, Erin, Truong, Hau, Toor, Jugmohit S., Tripathi, Sarvind, Nguyen, Son, Shen, Helena, Noel, Tiffany, Church, Nicole L., Weiner, Amber, Kendsersky, Nathan, Martinez, Dan, Weisberg, Rebecca, Christie, Molly, Eisenlohr, Laurence, Bosse, Kristopher R., Dimitrov, Dimiter S., Stevanovic, Stefan, Sgourakis, Nikolaos G., Kiefel, Ben R., Maris, John M.
Publicado 2021

Germline pathogenic variants in 786 neuroblastoma patients

por Kim, Jung, Vaksman, Zalman, Egolf, Laura E., Kaufman, Rebecca, Evans, J. Perry, Conkrite, Karina L., Danesh, Arnavaz, Lopez, Gonzalo, Randall, Michael P., Dent, Maiah H., Farra, Lance M., Menghani, Neil, Dymek, Malwina, Desai, Heena, Hausler, Ryan, Auvil, Jaime Guidry, Gerhard, Daniela S., Hakonarson, Hakon, Maxwell, Kara N., Cole, Kristina A., Pugh, Trevor J., Bosse, Kristopher R., Khan, Javed, Wei, Jun S., Maris, John M., Stewart, Douglas R., Diskin, Sharon J.
Publicado 2023