Paramagnetic NMR in drug discovery

por Softley, Charlotte A., Bostock, Mark J., Popowicz, Grzegorz M., Sattler, Michael
Publicado 2020

Structure determination of the seven-helical transmembrane receptor sensory rhodopsin II by solution NMR spectroscopy

por Gautier, Antoine, Mott, Helen R., Bostock, Mark J., Kirkpatrick, John P., Nietlispach, Daniel
Publicado 2010

Insight into partial agonism by observing multiple equilibria for ligand-bound and G(s)-mimetic nanobody-bound β(1)-adrenergic receptor

por Solt, Andras S., Bostock, Mark J., Shrestha, Binesh, Kumar, Prashant, Warne, Tony, Tate, Christopher G., Nietlispach, Daniel
Publicado 2017

The intrinsically disordered region of GCE protein adopts a more fixed structure by interacting with the LBD of the nuclear receptor FTZ-F1

por Kolonko, Marta, Bystranowska, Dominika, Taube, Michał, Kozak, Maciej, Bostock, Mark, Popowicz, Grzegorz, Ożyhar, Andrzej, Greb-Markiewicz, Beata
Publicado 2020

Structural Insights into the Mechanism of Negative Regulation of Single-box High Mobility Group Proteins by the Acidic Tail Domain

por Stott, Katherine, Watson, Matthew, Bostock, Mark J., Mortensen, Simon A., Travers, Andrew, Grasser, Klaus D., Thomas, Jean O.
Publicado 2014

Conformational plasticity of ligand-bound and ternary GPCR complexes studied by (19)F NMR of the β(1)-adrenergic receptor

por Frei, J. Niclas, Broadhurst, Richard W., Bostock, Mark J., Solt, Andras, Jones, Andrew J. Y., Gabriel, Florian, Tandale, Aditi, Shrestha, Binesh, Nietlispach, Daniel
Publicado 2020

Latency, thermal stability, and identification of an inhibitory compound of mirolysin, a secretory protease of the human periodontopathogen Tannerella forsythia

por Zak, Krzysztof M., Bostock, Mark J., Waligorska, Irena, Thøgersen, Ida B., Enghild, Jan J., Popowicz, Grzegorz M., Grudnik, Przemyslaw, Potempa, Jan, Ksiazek, Miroslaw
Publicado 2021

Structure and Molecular Recognition Mechanism of IMP-13 Metallo-β-Lactamase

por Softley, Charlotte A., Zak, Krzysztof M., Bostock, Mark J., Fino, Roberto, Zhou, Richard Xu, Kolonko, Marta, Mejdi-Nitiu, Ramona, Meyer, Hannelore, Sattler, Michael, Popowicz, Grzegorz M.
Publicado 2020

New vehicles allow detergent-free mass spectrometry of membrane protein complexes

por Hopper, Jonathan T.S., Yu, Yvonne Ting-Chun, Li, Dianfan, Raymond, Alison, Bostock, Mark, Liko, Idlir, Mikhailov, Victor, Laganowsky, Arthur, Benesch, Justin L.P., Caffrey, Martin, Nietlispach, Daniel, Robinson, Carol V.
Publicado 2013

Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

por Liwocha, Joanna, Krist, David T., van der Heden van Noort, Gerbrand J., Hansen, Fynn M., Truong, Vinh H., Karayel, Ozge, Purser, Nicholas, Houston, Daniel, Burton, Nicole, Bostock, Mark J., Sattler, Michael, Mann, Matthias, Harrison, Joseph S., Kleiger, Gary, Ovaa, Huib, Schulman, Brenda A.
Publicado 2020

NUScon: a community-driven platform for quantitative evaluation of nonuniform sampling in NMR

por Pustovalova, Yulia, Delaglio, Frank, Craft, D. Levi, Arthanari, Haribabu, Bax, Ad, Billeter, Martin, Bostock, Mark J., Dashti, Hesam, Hansen, D. Flemming, Hyberts, Sven G., Johnson, Bruce A., Kazimierczuk, Krzysztof, Lu, Hengfa, Maciejewski, Mark, Miljenović, Tomas M., Mobli, Mehdi, Nietlispach, Daniel, Orekhov, Vladislav, Powers, Robert, Qu, Xiaobo, Robson, Scott Anthony, Rovnyak, David, Wagner, Gerhard, Ying, Jinfa, Zambrello, Matthew, Hoch, Jeffrey C., Donoho, David L., Schuyler, Adam D.
Publicado 2021

Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses

por Napolitano, Valeria, Dabrowska, Agnieszka, Schorpp, Kenji, Mourão, André, Barreto-Duran, Emilia, Benedyk, Malgorzata, Botwina, Pawel, Brandner, Stefanie, Bostock, Mark, Chykunova, Yuliya, Czarna, Anna, Dubin, Grzegorz, Fröhlich, Tony, Hölscher, Michael, Jedrysik, Malwina, Matsuda, Alex, Owczarek, Katarzyna, Pachota, Magdalena, Plettenburg, Oliver, Potempa, Jan, Rothenaigner, Ina, Schlauderer, Florian, Slysz, Klaudia, Szczepanski, Artur, Greve-Isdahl Mohn, Kristin, Blomberg, Bjorn, Sattler, Michael, Hadian, Kamyar, Popowicz, Grzegorz Maria, Pyrc, Krzysztof
Publicado 2022