Mast Cells: Pivotal Players in Cardiovascular Diseases

por Bot, Ilze, van Berkel, Theo J.C, Biessen, Erik A.L
Publicado 2008

Stress-induced mast cell activation contributes to atherosclerotic plaque destabilization

por Lagraauw, H. Maxime, Wezel, Anouk, van der Velden, Daniël, Kuiper, Johan, Bot, Ilze
Publicado 2019

Complement factor C5a induces atherosclerotic plaque disruptions

por Wezel, Anouk, de Vries, Margreet R, Lagraauw, H Maxime, Foks, Amanda C, Kuiper, Johan, Quax, Paul HA, Bot, Ilze
Publicado 2014

Antisense Oligonucleotide Inhibition of MicroRNA-494 Halts Atherosclerotic Plaque Progression and Promotes Plaque Stabilization

por van Ingen, Eva, Foks, Amanda C., Kröner, Mara J., Kuiper, Johan, Quax, Paul H.A., Bot, Ilze, Nossent, Anne Yaël
Publicado 2019

Agonistic Anti-TIGIT Treatment Inhibits T Cell Responses in LDLr Deficient Mice without Affecting Atherosclerotic Lesion Development

por Foks, Amanda C., Ran, Ingrid A., Frodermann, Vanessa, Bot, Ilze, van Santbrink, Peter J., Kuiper, Johan, van Puijvelde, Gijs H. M.
Publicado 2013

Mesenchymal Stem Cells Reduce Murine Atherosclerosis Development

por Frodermann, Vanessa, van Duijn, Janine, van Pel, Melissa, van Santbrink, Peter J., Bot, Ilze, Kuiper, Johan, de Jager, Saskia C. A.
Publicado 2015

Uremia does not affect neointima formation in mice

por Aarup, Annemarie, Nielsen, Carsten H., Bisgaard, Line S., Bot, Ilze, El-Ali, Henrik H., Kjaer, Andreas, Nielsen, Lars B., Pedersen, Tanja X.
Publicado 2017

Local Mast Cell Activation Promotes Neovascularization

por Bot, Ilze, van der Velden, Daniël, Bouwman, Merel, Kröner, Mara J., Kuiper, Johan, Quax, Paul H. A., de Vries, Margreet R.
Publicado 2020

Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response

por Wezel, Anouk, de Vries, Margreet R., Maassen, Johanna M., Kip, Peter, Peters, Erna A., Karper, Jacco C., Kuiper, Johan, Bot, Ilze, Quax, Paul H. A.
Publicado 2016

Mast cell depletion in the preclinical phase of collagen-induced arthritis reduces clinical outcome by lowering the inflammatory cytokine profile

por van der Velden, Daniël, Lagraauw, H. Maxime, Wezel, Anouk, Launay, Pierre, Kuiper, Johan, Huizinga, Tom W. J., Toes, René E. M., Bot, Ilze, Stoop, Jeroen N.
Publicado 2016

Defective Autophagy in T Cells Impairs the Development of Diet-Induced Hepatic Steatosis and Atherosclerosis

por Amersfoort, Jacob, Douna, Hidde, Schaftenaar, Frank H., Foks, Amanda C., Kröner, Mara J., van Santbrink, Peter J., van Puijvelde, Gijs H. M., Bot, Ilze, Kuiper, Johan
Publicado 2018

Inhibition of lysophosphatidic acid receptors 1 and 3 attenuates atherosclerosis development in LDL-receptor deficient mice

por Kritikou, Eva, van Puijvelde, Gijs H. M., van der Heijden, Thomas, van Santbrink, Peter J., Swart, Maarten, Schaftenaar, Frank H., Kröner, Mara J., Kuiper, Johan, Bot, Ilze
Publicado 2016

Myocardial regeneration by transplantation of modified endothelial progenitor cells expressing SDF-1 in a rat model

por Schuh, Alexander, Kroh, Andreas, Konschalla, Simone, Liehn, Elisa A, Sobota, Radoslav M, Biessen, Erik AL, Bot, Ilze, Sönmez, Tolga Taha, Schober, Andreas, Marx, Nikolaus, Weber, Christian, Sasse, Alexander
Publicado 2012

Induction of HLA-A2 restricted CD8 T cell responses against ApoB100 peptides does not affect atherosclerosis in a humanized mouse model

por Schaftenaar, Frank H., Amersfoort, Jacob, Douna, Hidde, Kröner, Mara J., Foks, Amanda C., Bot, Ilze, Slütter, Bram A., van Puijvelde, Gijs H. M., Drijfhout, Jan W., Kuiper, Johan
Publicado 2019

Blockade of the BLT1-LTB(4) axis does not affect mast cell migration towards advanced atherosclerotic lesions in LDLr(−/−) mice

por Depuydt, Marie A. C., Vlaswinkel, Femke D., Hemme, Esmeralda, Delfos, Lucie, Kleijn, Mireia N. A. Bernabé, van Santbrink, Peter J., Foks, Amanda C., Slütter, Bram, Kuiper, Johan, Bot, Ilze
Publicado 2022

Stimulation of the PD-1 Pathway Decreases Atherosclerotic Lesion Development in Ldlr Deficient Mice

por Grievink, Hendrika W., Smit, Virginia, Verwilligen, Robin A. F., Bernabé Kleijn, Mireia N. A., Smeets, Diede, Binder, Christoph J., Yagita, Hideo, Moerland, Matthijs, Kuiper, Johan, Bot, Ilze, Foks, Amanda C.
Publicado 2021

Inhibition of microRNA-494-3p activates Wnt signaling and reduces proinflammatory macrophage polarization in atherosclerosis

por van Ingen, Eva, Foks, Amanda C., Woudenberg, Tamar, van der Bent, M. Leontien, de Jong, Alwin, Hohensinner, Philipp J., Wojta, Johann, Bot, Ilze, Quax, Paul.H.A., Nossent, Anne Yaël
Publicado 2021

Tc17 CD8(+) T cells accumulate in murine atherosclerotic lesions, but do not contribute to early atherosclerosis development

por van Duijn, Janine, de Jong, Maaike J M, Benne, Naomi, Leboux, Romain J T, van Ooijen, Marieke E, Kruit, Nicky, Foks, Amanda C, Jiskoot, Wim, Bot, Ilze, Kuiper, Johan, Slütter, Bram
Publicado 2020

IFNγ-Stimulated B Cells Inhibit T Follicular Helper Cells and Protect Against Atherosclerosis

por Douna, Hidde, de Mol, J., Amersfoort, Jacob, Schaftenaar, Frank H., Kiss, Mate G., Suur, Bianca E., Kroner, Mara J., Binder, Christoph J., Bot, Ilze, Van Puijvelde, Gijs H. M., Kuiper, Johan, Foks, Amanda C.
Publicado 2022

Diet-induced dyslipidemia induces metabolic and migratory adaptations in regulatory T cells

por Amersfoort, Jacob, Schaftenaar, Frank H, Douna, Hidde, van Santbrink, Peter J, van Puijvelde, Gijs H M, Slütter, Bram, Foks, Amanda C, Harms, Amy, Moreno-Gordaliza, Estefania, Wang, Yanyan, Hankemeier, Thomas, Bot, Ilze, Chi, Hongbo, Kuiper, Johan
Publicado 2020