Intrinsically Disordered and Aggregation Prone Regions Underlie β-Aggregation in S100 Proteins

por Carvalho, Sofia B., Botelho, Hugo M., Leal, Sónia S., Cardoso, Isabel, Fritz, Günter, Gomes, Cláudio M.
Publicado 2013

Absence of EPAC1 Signaling to Stabilize CFTR in Intestinal Organoids

por Ferreira, João F., Silva, Iris A. L., Botelho, Hugo M., Amaral, Margarida D., Farinha, Carlos M.
Publicado 2022

Edible Seaweeds Extracts: Characterization and Functional Properties for Health Conditions

por Coelho, Mariana, Duarte, Ana Patrícia, Pinto, Sofia, Botelho, Hugo M., Reis, Catarina Pinto, Serralheiro, Maria Luísa, Pacheco, Rita
Publicado 2023

A Drug Screening Reveals Minocycline Hydrochloride as a Therapeutic Option to Prevent Breast Cancer Cells Extravasation across the Blood–Brain Barrier

por Godinho-Pereira, Joana, Lopes, Margarida Dionísio, Garcia, Ana Rita, Botelho, Hugo M., Malhó, Rui, Figueira, Inês, Brito, Maria Alexandra
Publicado 2022

Protein Traffic Disorders: an Effective High-Throughput Fluorescence Microscopy Pipeline for Drug Discovery

por Botelho, Hugo M., Uliyakina, Inna, Awatade, Nikhil T., Proença, Maria C., Tischer, Christian, Sirianant, Lalida, Kunzelmann, Karl, Pepperkok, Rainer, Amaral, Margarida D.
Publicado 2015

Exploring YAP1-centered networks linking dysfunctional CFTR to epithelial–mesenchymal transition

por Quaresma, Margarida C, Botelho, Hugo M, Pankonien, Ines, Rodrigues, Cláudia S, Pinto, Madalena C, Costa, Pau R, Duarte, Aires, Amaral, Margarida D
Publicado 2022

Full Rescue of F508del-CFTR Processing and Function by CFTR Modulators Can Be Achieved by Removal of Two Regulatory Regions

por Uliyakina, Inna, Botelho, Hugo M., da Paula, Ana C., Afonso, Sara, Lobo, Miguel J., Felício, Verónica, Farinha, Carlos M., Amaral, Margarida D.
Publicado 2020

Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum

por Santos, João D., Canato, Sara, Carvalho, Ana S., Botelho, Hugo M., Aloria, Kerman, Amaral, Margarida D., Matthiesen, Rune, Falcao, Andre O., Farinha, Carlos M.
Publicado 2019

Searching for a Paradigm Shift in Auger-Electron Cancer Therapy with Tumor-Specific Radiopeptides Targeting the Mitochondria and/or the Cell Nucleus

por Fernandes, Célia, Palma, Elisa, Silva, Francisco, Belchior, Ana, Pinto, Catarina I. G., Guerreiro, Joana F., Botelho, Hugo M., Mendes, Filipa, Raposinho, Paula, Paulo, António
Publicado 2022

Biochemical and Biophysical Characterization of Recombinant Yeast Proteasome Maturation Factor Ump1

por Sá-Moura, Bebiana, Simões, Ana Marisa, Fraga, Joana, Fernandes, Humberto, Abreu, Isabel A., Botelho, Hugo M., Gomes, Cláudio M., Marques, António J., Dohmen, R. Jürgen, Ramos, Paula C., Macedo-Ribeiro, Sandra
Publicado 2013

The neuronal S100B protein is a calcium-tuned suppressor of amyloid-β aggregation

por Cristóvão, Joana S., Morris, Vanessa K., Cardoso, Isabel, Leal, Sónia S., Martínez, Javier, Botelho, Hugo M., Göbl, Christoph, David, Rodrigo, Kierdorf, Katrin, Alemi, Mobina, Madl, Tobias, Fritz, Günter, Reif, Bernd, Gomes, Cláudio M.
Publicado 2018

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

por Lim, Sang Hyun, Snider, Jamie, Birimberg‐Schwartz, Liron, Ip, Wan, Serralha, Joana C, Botelho, Hugo M, Lopes‐Pacheco, Miquéias, Pinto, Madalena C, Moutaoufik, Mohamed Taha, Zilocchi, Mara, Laselva, Onofrio, Esmaeili, Mohsen, Kotlyar, Max, Lyakisheva, Anna, Tang, Priscilla, López Vázquez, Lucía, Akula, Indira, Aboualizadeh, Farzaneh, Wong, Victoria, Grozavu, Ingrid, Opacak‐Bernardi, Teuta, Yao, Zhong, Mendoza, Meg, Babu, Mohan, Jurisica, Igor, Gonska, Tanja, Bear, Christine E, Amaral, Margarida D, Stagljar, Igor
Publicado 2022