The Lysosome Signaling Platform: Adapting With the Times

por Inpanathan, Subothan, Botelho, Roberto J.
Publicado 2019

Critical role for scaffolding adapter Gab2 in FcγR-mediated phagocytosis

por Gu, Haihua, Botelho, Roberto J., Yu, Min, Grinstein, Sergio, Neel, Benjamin G.
Publicado 2003

AMPK is required for recovery from metabolic stress induced by ultrasound microbubble treatment

por Lo, Louis, Uchenunu, Oro, Botelho, Roberto J., Antonescu, Costin N., Karshafian, Raffi
Publicado 2022

Inhibition of lipid kinase PIKfyve reveals a role for phosphatase Inpp4b in the regulation of PI(3)P-mediated lysosome dynamics through VPS34 activity

por Saffi, Golam T., Wang, Cheng An, Mangialardi, Emily M., Vacher, Jean, Botelho, Roberto J., Salmena, Leonardo
Publicado 2022

Reactive oxygen species prevent lysosome coalescence during PIKfyve inhibition

por Saffi, Golam T., Tang, Evan, Mamand, Sami, Inpanathan, Subothan, Fountain, Aaron, Salmena, Leonardo, Botelho, Roberto J.
Publicado 2021

mTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells

por Saric, Amra, Hipolito, Victoria E. B., Kay, Jason G., Canton, Johnathan, Antonescu, Costin N., Botelho, Roberto J.
Publicado 2016

Localized Biphasic Changes in Phosphatidylinositol-4,5-Bisphosphate at Sites of Phagocytosis

por Botelho, Roberto J., Teruel, Mary, Dierckman, Renee, Anderson, Richard, Wells, Alan, York, John D., Meyer, Tobias, Grinstein, Sergio
Publicado 2000

pH of endophagosomes controls association of their membranes with Vps34 and PtdIns(3)P levels

por Naufer, Amriya, Hipolito, Victoria E.B., Ganesan, Suriakarthiga, Prashar, Akriti, Zaremberg, Vanina, Botelho, Roberto J., Terebiznik, Mauricio R.
Publicado 2018

The PH domain from the Toxoplasma gondii PH-containing protein-1 (TgPH1) serves as an ectopic reporter of phosphatidylinositol 3-phosphate in mammalian cells

por Chintaluri, Krishna, Goulden, Brady D., Celmenza, Camilyn, Saffi, Golam, Miraglia, Emily, Hammond, Gerald R. V., Botelho, Roberto J.
Publicado 2018

Correction: The PH domain from the Toxoplasma gondii PH-containing protein-1 (TgPH1) serves as an ectopic reporter of phosphatidylinositol 3-phosphate in mammalian cells

por Chintaluri, Krishna, Goulden, Brady D., Clemenza, Camilyn, Saffi, Golam, Miraglia, Emily, Hammond, Gerald R. V., Botelho, Roberto J.
Publicado 2018

Characterization of a PIP Binding Site in the N-Terminal Domain of V-ATPase a4 and Its Role in Plasma Membrane Association

por Chu, Anh, Yao, Yeqi, Saffi, Golam T., Chung, Ji Hyun, Botelho, Roberto J., Glibowicka, Miroslawa, Deber, Charles M., Manolson, Morris F.
Publicado 2023

The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic

por Bone, Leslie N., Dayam, Roya M., Lee, Minhyoung, Kono, Nozomu, Fairn, Gregory D., Arai, Hiroyuki, Botelho, Roberto J., Antonescu, Costin N.
Publicado 2017

Síndromes Coronarianas Agudas no Contexto Atual da Pandemia COVID-19

por Guimarães, Raphael Boesche, Falcão, Breno, Costa, Ricardo Alves, Lopes, Marcelo Antônio Cartaxo Queiroga, Botelho, Roberto Vieira, Petraco, Ricardo, Sarmento-Leite, Rogério
Publicado 2020

Phosphatidylinositol-4,5-bisphosphate hydrolysis directs actin remodeling during phagocytosis

por Scott, Cameron C., Dobson, Wendy, Botelho, Roberto J., Coady-Osberg, Natasha, Chavrier, Philippe, Knecht, David A., Heath, Colin, Stahl, Philip, Grinstein, Sergio
Publicado 2005

Selective regulation of clathrin-mediated epidermal growth factor receptor signaling and endocytosis by phospholipase C and calcium

por Delos Santos, Ralph Christian, Bautista, Stephen, Lucarelli, Stefanie, Bone, Leslie N., Dayam, Roya M., Abousawan, John, Botelho, Roberto J., Antonescu, Costin N.
Publicado 2017

Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes

por Lancaster, Charlene E., Fountain, Aaron, Dayam, Roaya M., Somerville, Elliott, Sheth, Javal, Jacobelli, Vanessa, Somerville, Alex, Terebiznik, Mauricio R., Botelho, Roberto J.
Publicado 2021

An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis

por Fairn, Gregory D., Ogata, Koji, Botelho, Roberto J., Stahl, Philip D., Anderson, Richard A., De Camilli, Pietro, Meyer, Tobias, Wodak, Shoshana, Grinstein, Sergio
Publicado 2009

Improved imaging and preservation of lysosome dynamics using silver nanoparticle-enhanced fluorescence

por Soha, Sumaiya A., Santhireswaran, Araniy, Huq, Saaimatul, Casimir-Powell, Jayde, Jenkins, Nicala, Hodgson, Gregory K., Sugiyama, Michael, Antonescu, Costin N., Impellizzeri, Stefania, Botelho, Roberto J.
Publicado 2023

Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

por Vieira, Otilia V., Botelho, Roberto J., Rameh, Lucia, Brachmann, Saskia M., Matsuo, Tsuyoshi, Davidson, Howard W., Schreiber, Alan, Backer, Jonathan M., Cantley, Lewis C., Grinstein, Sergio
Publicado 2001

Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation

por Hipolito, Victoria E. B., Diaz, Jacqueline A., Tandoc, Kristofferson V., Oertlin, Christian, Ristau, Johannes, Chauhan, Neha, Saric, Amra, Mclaughlan, Shannon, Larsson, Ola, Topisirovic, Ivan, Botelho, Roberto J.
Publicado 2019