Probing the gating mechanism of the mechanosensitive channel Piezo1 with the small molecule Yoda1

por Lacroix, Jerome J., Botello-Smith, Wesley M., Luo, Yun
Publicado 2018

Polymodal allosteric regulation of Type 1 Serine/Threonine Kinase Receptors via a conserved electrostatic lock

por Botello-Smith, Wesley M., Alsamarah, Abdelaziz, Chatterjee, Payal, Xie, Chen, Lacroix, Jerome J., Hao, Jijun, Luo, Yun
Publicado 2017

Molecular Mechanism of Resveratrol’s Lipid Membrane Protection

por Fei, Qinqin, Kent, David, Botello-Smith, Wesley M., Nur, Fariah, Nur, Saadia, Alsamarah, Abdelaziz, Chatterjee, Payal, Lambros, Maria, Luo, Yun
Publicado 2018

A mechanism for the activation of the mechanosensitive Piezo1 channel by the small molecule Yoda1

por Botello-Smith, Wesley M., Jiang, Wenjuan, Zhang, Han, Ozkan, Alper D., Lin, Yi-Chun, Pham, Christine N., Lacroix, Jérôme J., Luo, Yun
Publicado 2019

The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening

por Valdez Capuccino, Juan M., Chatterjee, Payal, García, Isaac E., Botello-Smith, Wesley M., Zhang, Han, Harris, Andrew L., Luo, Yun, Contreras, Jorge E.
Publicado 2019

Crowding-induced opening of the mechanosensitive Piezo1 channel in silico

por Jiang, Wenjuan, Del Rosario, John Smith, Botello-Smith, Wesley, Zhao, Siyuan, Lin, Yi-chun, Zhang, Han, Lacroix, Jérôme, Rohacs, Tibor, Luo, Yun Lyna
Publicado 2021

In silico prediction of ARB resistance: A first step in creating personalized ARB therapy

por Anderson, Shane D., Tabassum, Asna, Yeon, Jae Kyung, Sharma, Garima, Santos, Priscilla, Soong, Tik Hang, Thu, Yin Win, Nies, Isaac, Kurita, Tomomi, Chandler, Andrew, Alsamarah, Abdelaziz, Kanassatega, Rhye-Samuel, Luo, Yun L., Botello-Smith, Wesley M., Andresen, Bradley T.
Publicado 2020