A unique melanocortin-4-receptor signaling profile for obesity-associated constitutively active variants

por Botha, Rikus, Kumar, Shree S, Grimsey, Natasha L, Mountjoy, Kathleen G
Publicado 2023

hMRAPα, but Not hMRAP2, Enhances hMC4R Constitutive Activity in HEK293 Cells and This Is Not Dependent on hMRAPα Induced Changes in hMC4R Complex N-linked Glycosylation

por Kay, Emma I., Botha, Rikus, Montgomery, Johanna M., Mountjoy, Kathleen G.
Publicado 2015

SAT-598 Shared Signaling Profile Between Human MRAPα-Induced Human MC4R Constitutive Activity and Obesity-Associated Human MC4R Constitutive Activity

por Botha, Rikus, Kumar, Shree S, Grimsey, Natasha, Kay, Emma I, Mountjoy, Kathleen Grace
Publicado 2020

Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance

por Mountjoy, Kathleen G., Caron, Alexandre, Hubbard, Kristina, Shome, Avik, Grey, Angus C., Sun, Bo, Bould, Sarah, Middleditch, Martin, Pontré, Beau, McGregor, Ailsa, Harris, Paul W.R., Kowalczyk, Renata, Brimble, Margaret A., Botha, Rikus, Tan, Karen M.L., Piper, Sarah J., Buchanan, Christina, Lee, Syann, Coll, Anthony P., Elmquist, Joel K.
Publicado 2017