Pretreatment and Coadministration With Methotrexate Improved Durability of Pegloticase Response: An Observational, Proof-of-Concept Case Series

por Botson, John K., Peterson, Jeff
Publicado 2022

Dual-energy CT assessment of rapid monosodium urate depletion and bone erosion remodelling during pegloticase plus methotrexate co-therapy

por Dalbeth, Nicola, Becce, Fabio, Botson, John K, Zhao, Lin, Kumar, Ada
Publicado 2022

Improved joint and patient-reported health assessments with pegloticase plus methotrexate co-therapy in patients with uncontrolled gout: 12-month exploratory outcomes of the MIRROR...

por Botson, John K., Obermeyer, Katie, LaMoreaux, Brian, Zhao, Lin, Weinblatt, Michael E., Peterson, Jeff
Publicado 2022

A Randomized, Double‐Blind, Placebo‐Controlled Multicenter Efficacy and Safety Study of Methotrexate to Increase Response Rates in Patients With Uncontrolled Gout Receiving Pegloti...

por Botson, John K., Saag, Kenneth, Peterson, Jeff, Obermeyer, Katie, Xin, Yan, LaMoreaux, Brian, Padnick‐Silver, Lissa, Verma, Supra, Grewal, Suneet, Majjhoo, Amar, Tesser, John R. P., Weinblatt, Michael E.
Publicado 2023

Expert Opinion on Pegloticase with Concomitant Immunomodulatory Therapy in the Treatment of Uncontrolled Gout to Improve Efficacy, Safety, and Durability of Response

por Botson, John K., Baraf, Herbert S. B., Keenan, Robert T., Albert, John, Masri, Karim R., Peterson, Jeff, Yung, Christianne, Freyne, Brigid, Amin, Mona, Abdellatif, Abdul, Soloman, Nehad, Edwards, N. Lawrence, Strand, Vibeke
Publicado 2022

A multicentre, efficacy and safety study of methotrexate to increase response rates in patients with uncontrolled gout receiving pegloticase (MIRROR): 12-month efficacy, safety, im...

por Botson, John K., Tesser, John R. P., Bennett, Ralph, Kenney, Howard M., Peloso, Paul M., Obermeyer, Katie, Song, Yang, LaMoreaux, Brian, Zhao, Lin, Xin, Yan, Chamberlain, Jason, Ramanathan, Srini, Weinblatt, Michael E., Peterson, Jeff
Publicado 2022

A Randomized, Placebo‐Controlled Study of Methotrexate to Increase Response Rates in Patients with Uncontrolled Gout Receiving Pegloticase: Primary Efficacy and Safety Findings

por Botson, John K., Saag, Kenneth, Peterson, Jeff, Parikh, Naval, Ong, Stephen, La, Dan, LoCicero, Karon, Obermeyer, Katie, Xin, Yan, Chamberlain, Jason, LaMoreaux, Brian, Verma, Supra, Sainati, Stephen, Grewal, Suneet, Majjhoo, Amar, Tesser, John R. P., Weinblatt, Michael E.
Publicado 2022

Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF

por Song, Yun-Jeong, Choi, In Ah., Meylan, Françoise, Demoruelle, M. Kristen, Farley, Taylor, Richard, Arianne C., Hawley, Eric, Botson, John, Hong, Yoo Jin, Lee, Eun Young, Mian, Sabina R., Hamilton, Bartlett C., Thiele, Geoffrey M., Mikuls, Ted R., Gara, Naveen, Ward, Chris D., Lamberth, Sarah, Deane, Kevin D., Heller, Theo, Ward, Michael M., Lee, David M., Migone, Thi-Sau, Stohl, William, O’Dell, James R., Norris, Jill M., Holers, V. Michael, Gregersen, Peter, Song, Yeong-Wook, Siegel, Richard M.
Publicado 2020