Inhibition of SIRT2 in merlin/NF2-mutant Schwann cells triggers necrosis

por Petrilli, Alejandra M., Bott, Marga, Fernández-Valle, Cristina
Publicado 2013

Stability of the tumor suppressor merlin depends on its ability to bind paxillin LD3 and associate with β1 integrin and actin at the plasma membrane

por Manetti, Maria Elisa, Geden, Sandra, Bott, Marga, Sparrow, Nicklaus, Lambert, Stephen, Fernandez-Valle, Cristina
Publicado 2012

Ponatinib promotes a G(1) cell-cycle arrest of merlin/NF2-deficient human schwann cells

por Petrilli, Alejandra M, Garcia, Jeanine, Bott, Marga, Plati, Stephani Klingeman, Dinh, Christine T, Bracho, Olena R, Yan, Denise, Zou, Bing, Mittal, Rahul, Telischi, Fred F, Liu, Xue-Zhong, Chang, Long-Sheng, Bradley, D Welling, Copik, Alicja J, Fernández-Valle, Cristina
Publicado 2017

Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2

por Allaway, Robert, Angus, Steve P., Beauchamp, Roberta L., Blakeley, Jaishri O., Bott, Marga, Burns, Sarah S., Carlstedt, Annemarie, Chang, Long-Sheng, Chen, Xin, Clapp, D. Wade, Desouza, Patrick A., Erdin, Serkan, Fernandez-Valle, Cristina, Guinney, Justin, Gusella, James F., Haggarty, Stephen J., Johnson, Gary L., La Rosa, Salvatore, Morrison, Helen, Petrilli, Alejandra M., Plotkin, Scott R., Pratap, Abhishek, Ramesh, Vijaya, Sciaky, Noah, Stemmer-Rachamimov, Anat, Stuhlmiller, Tim J., Talkowski, Michael E., Welling, D. Bradley, Yates, Charles W., Zawistowski, Jon S., Zhao, Wen-Ning
Publicado 2018