A family of E. coli expression vectors for laboratory scale and high throughput soluble protein production

por Cabrita, Lisa D, Dai, Weiwen, Bottomley, Stephen P
Publicado 2006

Conformational Behavior and Aggregation of Ataxin-3 in SDS

por Saunders, Helen M., Hughes, Victoria A., Cappai, Roberto, Bottomley, Stephen P.
Publicado 2013

The Z Mutation Alters the Global Structural Dynamics of α(1)-Antitrypsin

por Hughes, Victoria A., Meklemburg, Robert, Bottomley, Stephen P., Wintrode, Patrick L.
Publicado 2014

Probing the folding pathway of a consensus serpin using single tryptophan mutants

por Yang, Li, Irving, James A., Dai, Weiwen, Aguilar, Marie-Isabel, Bottomley, Stephen P.
Publicado 2018

The Roles of Helix I and Strand 5A in the Folding, Function and Misfolding of α(1)-Antitrypsin

por Knaupp, Anja S., Keleher, Shani, Yang, Li, Dai, Weiwen, Bottomley, Stephen P., Pearce, Mary C.
Publicado 2013

PolyQ: a database describing the sequence and domain context of polyglutamine repeats in proteins

por Robertson, Amy L., Bate, Mark A., Androulakis, Steve G., Bottomley, Stephen P., Buckle, Ashley M.
Publicado 2011

PFD: a database for the investigation of protein folding kinetics and stability

por Fulton, Kate F., Devlin, Glyn L., Jodun, Rachel A., Silvestri, Linda, Bottomley, Stephen P., Fersht, Alan R., Buckle, Ashley M.
Publicado 2005

Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells

por Samson, Andre L., Ho, Bosco, Au, Amanda E., Schoenwaelder, Simone M., Smyth, Mark J., Bottomley, Stephen P., Kleifeld, Oded, Medcalf, Robert L.
Publicado 2016

The REFOLD database: a tool for the optimization of protein expression and refolding

por Chow, Michelle K. M., Amin, Abdullah A., Fulton, Kate F., Fernando, Thushan, Kamau, Lawrence, Batty, Chris, Louca, Michael, Ho, Storm, Whisstock, James C., Bottomley, Stephen P., Buckle, Ashley M.
Publicado 2006

The N terminus of the serpin, tengpin, functions to trap the metastable native state

por Zhang, Qingwei, Buckle, Ashley M, Law, Ruby H P, Pearce, Mary C, Cabrita, Lisa D, Lloyd, Gordon J, Irving, James A, Smith, A Ian, Ruzyla, Katya, Rossjohn, Jamie, Bottomley, Stephen P, Whisstock, James C
Publicado 2007

Conformational Change in the Chromatin Remodelling Protein MENT

por Ong, Poh Chee, Golding, Sarah J., Pearce, Mary C., Irving, James A., Grigoryev, Sergei A., Pike, Debbie, Langendorf, Christopher G., Bashtannyk-Puhalovich, Tanya A., Bottomley, Stephen P., Whisstock, James C., Pike, Robert N., McGowan, Sheena
Publicado 2009

Recombinant protein quality evaluation: proposal for a minimal information standard

por Buckle, Ashley M., Bate, Mark A., Androulakis, Steve, Cinquanta, Mario, Basquin, Jerome, Bonneau, Fabien, Chatterjee, Deb K., Cittaro, Davide, Gräslund, Susanne, Gruszka, Alicja, Page, Rebecca, Suppmann, Sabine, Wheeler, Jun X., Agostini, Deborah, Taussig, Mike, Taylor, Chris F., Bottomley, Stephen P., Villaverde, Antonio, de Marco, Ario
Publicado 2011

Natural HLA Class I Polymorphism Controls the Pathway of Antigen Presentation and Susceptibility to Viral Evasion

por Zernich, Danielle, Purcell, Anthony W., Macdonald, Whitney A., Kjer-Nielsen, Lars, Ely, Lauren K., Laham, Nihay, Crockford, Tanya, Mifsud, Nicole A., Bharadwaj, Mandvi, Chang, Linus, Tait, Brian D., Holdsworth, Rhonda, Brooks, Andrew G., Bottomley, Stephen P., Beddoe, Travis, Peh, Chen Au, Rossjohn, Jamie, McCluskey, James
Publicado 2004

Smoothing a rugged protein folding landscape by sequence-based redesign

por Porebski, Benjamin T., Keleher, Shani, Hollins, Jeffrey J., Nickson, Adrian A., Marijanovic, Emilia M., Borg, Natalie A., Costa, Mauricio G. S., Pearce, Mary A., Dai, Weiwen, Zhu, Liguang, Irving, James A., Hoke, David E., Kass, Itamar, Whisstock, James C., Bottomley, Stephen P., Webb, Geoffrey I., McGowan, Sheena, Buckle, Ashley M.
Publicado 2016

The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates

por Kennan, Ruth M., Wong, Wilson, Dhungyel, Om P., Han, Xiaoyan, Wong, David, Parker, Dane, Rosado, Carlos J., Law, Ruby H. P., McGowan, Sheena, Reeve, Shane B., Levina, Vita, Powers, Glenn A., Pike, Robert N., Bottomley, Stephen P., Smith, A. Ian, Marsh, Ian, Whittington, Richard J., Whisstock, James C., Porter, Corrine J., Rood, Julian I.
Publicado 2010