Targeting Dysregulation of Metalloproteinase Activity in Osteoarthritis

por Yamamoto, Kazuhiro, Wilkinson, David, Bou-Gharios, George
Publicado 2020

SIRT1 directly activates autophagy in human chondrocytes

por Sacitharan, Pradeep K., Bou-Gharios, George, Edwards, James R.
Publicado 2020

JunB mediates enhancer/promoter activity of COL1A2 following TGF-β induction

por Ponticos, Markella, Harvey, Clare, Ikeda, Tetsuro, Abraham, David, Bou-Gharios, George
Publicado 2009

Aggrecanase-selective tissue inhibitor of metalloproteinase-3 (TIMP3) protects articular cartilage in a surgical mouse model of osteoarthritis

por Nakamura, Hiroyuki, Vo, Phoung, Kanakis, Ioannis, Liu, Ke, Bou-Gharios, George
Publicado 2020

MiR-18a-5p Targets Connective Tissue Growth Factor Expression and Inhibits Transforming Growth Factor β2-Induced Trabecular Meshwork Cell Contractility

por Knox, John, Bou-Gharios, George, Hamill, Kevin J., Willoughby, Colin E.
Publicado 2022

Eribulin sensitizes oral squamous cell carcinoma cells to cetuximab via induction of mesenchymal-to-epithelial transition

por Kitahara, Hiroko, Hirai, Mariko, Kato, Koroku, Bou-Gharios, George, Nakamura, Hiroyuki, Kawashiri, Shuichi
Publicado 2016

First decade anniversary of the United Kingdom National Alkaptonuria Centre

por Khedr, Milad, Sireau, Nick, Bou‐Gharios, George, Gallagher, Jim A., Ranganath, Lakshminarayan R.
Publicado 2023

High doses of TGF-β potently suppress type I collagen via the transcription factor CUX1

por Fragiadaki, Maria, Ikeda, Tetsurou, Witherden, Abigail, Mason, Roger M, Abraham, David, Bou-Gharios, George
Publicado 2011

Distant Mesenchymal Progenitors Contribute to Skin Wound Healing and Produce Collagen: Evidence from a Murine Fetal Microchimerism Model

por Seppanen, Elke, Roy, Edwige, Ellis, Rebecca, Bou-Gharios, George, Fisk, Nicholas M., Khosrotehrani, Kiarash
Publicado 2013

The Chondro-Osseous Continuum: Is It Possible to Unlock the Potential Assigned Within?

por Javaheri, Behzad, Caetano-Silva, Soraia P., Kanakis, Ioannis, Bou-Gharios, George, Pitsillides, Andrew A.
Publicado 2018

Regulation of PD-L1 expression in a high-grade invasive human oral squamous cell carcinoma microenvironment

por Hirai, Mariko, Kitahara, Hiroko, Kobayashi, Yutaka, Kato, Koroku, Bou-Gharios, George, Nakamura, Hiroyuki, Kawashiri, Shuichi
Publicado 2016

Regulation of programmed-death ligand in the human head and neck squamous cell carcinoma microenvironment is mediated through matrix metalloproteinase-mediated proteolytic cleavage

por Hira-Miyazawa, Mayuko, Nakamura, Hiroyuki, Hirai, Mariko, Kobayashi, Yutaka, Kitahara, Hiroko, Bou-Gharios, George, Kawashiri, Shuichi
Publicado 2017

Expression of tyrosine pathway enzymes in mice demonstrates that homogentisate 1,2‐dioxygenase deficiency in the liver is responsible for homogentisic acid‐derived ochronotic pigme...

por Wilson, Peter J. M., Ranganath, Lakshminarayan R., Bou‐Gharios, George, Gallagher, James A., Hughes, Juliette H.
Publicado 2020

Differential tissue specific, temporal and spatial expression patterns of the Aggrecan gene is modulated by independent enhancer elements

por Li, Ian M. H., Liu, Ke, Neal, Alice, Clegg, Peter D., De Val, Sarah, Bou-Gharios, George
Publicado 2018

Meniscal and ligament modifications in spontaneous and post-traumatic mouse models of osteoarthritis

por Ramos-Mucci, Lorenzo, Javaheri, Behzad, van ‘t Hof, Rob, Bou-Gharios, George, Pitsillides, Andrew A., Comerford, Eithne, Poulet, Blandine
Publicado 2020

Histopathological dataset and demographic details of synovial tissues from patients with end-stage osteoarthritis, soft tissue and traumatic injuries of the knee

por Jamal, Juliana, Roebuck, Margaret M., Wood, Amanda, Santini, Alasdair, Bou-Gharios, George, Frostick, Simon P., Wong, Pooi-Fong
Publicado 2022

Hyperglycemia Causes Renal Cell Damage via CCN2-Induced Activation of the TrkA Receptor: Implications for Diabetic Nephropathy

por Fragiadaki, Maria, Hill, Nicola, Hewitt, Reiko, Bou-Gharios, George, Cook, Terence, Tam, Frederick W., Domin, Jan, Mason, Roger M.
Publicado 2012

Multiple enhancer regions govern the transcription of CCN2 during embryonic development

por Frost, Stephanie L., Liu, Ke, Li, Ian M. H., Poulet, Blandine, Comerford, Eithne, De Val, Sarah, Bou-Gharios, George
Publicado 2017

Selectively high efficacy of eribulin against high-grade invasive recurrent and/or metastatic squamous cell carcinoma of the head and neck

por Kobayashi, Yutaka, Kitahara, Hiroko, Hirai, Mariko, Tanaka, Akira, Jokaji, Rei, Kobayashi, Kazuhiko, Bou-Gharios, George, Nakamura, Hiroyuki, Kawashiri, Shuichi
Publicado 2019

The anterior cruciate ligament in murine post-traumatic osteoarthritis: markers and mechanics

por Ramos-Mucci, Lorenzo, Elsheikh, Ahmed, Keenan, Craig, Eliasy, Ashkan, D’Aout, Kristiaan, Bou-Gharios, George, Comerford, Eithne, Poulet, Blandine
Publicado 2022