Poly(ADP-ribose) polymerase as a novel regulator of 17β-estradiol-induced cell growth through a control of the estrogen receptor/IGF-1 receptor/PDZK1 axis

por Kim, Hogyoung, Tarhuni, Abdelmetalab, Abd Elmageed, Zakaria Y, Boulares, A Hamid
Publicado 2015

Angiotensin I–Converting Enzyme Type 2 (ACE2) Gene Therapy Improves Glycemic Control in Diabetic Mice

por Bindom, Sharell M., Hans, Chetan P., Xia, Huijing, Boulares, A. Hamid, Lazartigues, Eric
Publicado 2010

Potential of Inducible Nitric Oxide Synthase as a Therapeutic Target for Allergen-Induced Airway Hyperresponsiveness: A Critical Connection to Nitric Oxide Levels and PARP Activity

por Ibba, Salome' V., Ghonim, Mohamed A., Pyakurel, Kusma, Lammi, Matthew R., Mishra, Anil, Boulares, A. Hamid
Publicado 2016

Promotion of a synthetic degradation of activated STAT6 by PARP-1 inhibition: roles of poly(ADP-ribosyl)ation, calpains and autophagy

por Wang, Jeffrey, Ghonim, Mohamed A., Ibba, Salome V., Luu, Hanh H., Aydin, Yucel, Greer, Peter A., Boulares, A. Hamid
Publicado 2022

Sulfated non-anticoagulant heparin blocks Th2-induced asthma by modulating the IL-4/signal transducer and activator of transcription 6/Janus kinase 1 pathway

por Ghonim, Mohamed A., Wang, Jeffrey, Ibba, Salome V., Luu, Hanh H., Pyakurel, Kusma, Benslimane, Ilyes, Mousa, Shaker, Boulares, A. Hamid
Publicado 2018

HIGH FAT DIET INDUCES LUNG REMODELING IN APOE DEFICIENT MICE: AN ASSOCIATION WITH AN INCREASE IN CIRCULATORY AND LUNG INFLAMMATORY FACTORS

por Naura, Amarjit S., Hans, Chetan P., Zerfaoui, Mourad, Errami, Youssef, Ju, Jihang, Kim, Hogyoung, Matrougui, Khalid, Kim, Jong G., Boulares, A. Hamid
Publicado 2009

Repurposing ketoconazole as an exosome directed adjunct to sunitinib in treating renal cell carcinoma

por Greenberg, Jacob W., Kim, Hogyoung, Moustafa, Ahmed A., Datta, Amrita, Barata, Pedro C., Boulares, A. Hamid, Abdel-Mageed, Asim B., Krane, Louis S.
Publicado 2021

Protective Effects of PARP-1 Knockout on Dyslipidemia-Induced Autonomic and Vascular Dysfunction in ApoE(−/−) Mice: Effects on eNOS and Oxidative Stress

por Hans, Chetan P., Feng, Yumei, Naura, Amarjit S., Zerfaoui, Mourad, Rezk, Bashir M., Xia, Huijing, Kaye, Alan D., Matrougui, Khalid, Lazartigues, Eric, Boulares, A. Hamid
Publicado 2009

Combination of Tipifarnib and Sunitinib Overcomes Renal Cell Carcinoma Resistance to Tyrosine Kinase Inhibitors via Tumor-Derived Exosome and T Cell Modulation

por Greenberg, Jacob W., Kim, Hogyoung, Ahn, Miae, Moustafa, Ahmed A., Zhou, He, Barata, Pedro C., Boulares, A. Hamid, Abdel-Mageed, Asim B., Krane, Louis S.
Publicado 2022

PARP-1 Is Critical for Recruitment of Dendritic Cells to the Lung in a Mouse Model of Asthma but Dispensable for Their Differentiation and Function

por Echeverri Tirado, Laura C., Ghonim, Mohamed A., Wang, Jeffrey, Al-Khami, Amir A., Wyczechowska, Dorota, Luu, Hanh H., Kim, Hogyoung, Sanchez-Pino, Maria Dulfary, Yélamos, José, Yassin, Lina M., Boulares, A. Hamid
Publicado 2019

ICAD Deficiency in Human Colon Cancer and Predisposition to Colon Tumorigenesis: Linkage to Apoptosis Resistance and Genomic Instability

por Errami, Youssef, Brim, Hassan, Oumouna-Benachour, Karine, Oumouna, Mustapha, Naura, Amarjit S., Kim, Hogyoung, Ju, Jihang, Davis, Christian J., Kim, Jong G., Ashktorab, Hassan, Fallon, Kenneth, Xu, Ming, Zhang, Jianhua, Valle, Luis Del, Boulares, A. Hamid
Publicado 2013

Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer

por Ghonim, Mohamed A, Ibba, Salome V, Tarhuni, Abdelmetalab F, Errami, Youssef, Luu, Hanh H, Dean, Matthew J, El-Bahrawy, Ali H, Wyczechowska, Dorota, Benslimane, Ilyes A, Del Valle, Luis, Al-Khami, Amir A, Ochoa, Augusto C, Boulares, A Hamid
Publicado 2021

Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses

por Monticone, Giulia, Huang, Zhi, Csibi, Fred, Leit, Silvana, Ciccone, David, Champhekar, Ameya S., Austin, Jermaine E., Ucar, Deniz A., Hossain, Fokhrul, Ibba, Salome V., Boulares, A. Hamid, Carpino, Nicholas, Xu, Keli, Majumder, Samarpan, Osborne, Barbara A., Loh, Christine, Miele, Lucio
Publicado 2022

PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4(+) T cell function

por Ghonim, Mohamed A, Pyakurel, Kusma, Ibba, Salome V, Al-Khami, Amir A, Wang, Jeffrey, Rodriguez, Paulo, Rady, Hamada F, El-Bahrawy, Ali H, Lammi, Matthew R, Mansy, Moselhy S, Al-Ghareeb, Kamel, Ramsay, Alistair, Ochoa, Augusto, Naura, Amarjit S, Boulares, A Hamid
Publicado 2015

PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice

por Ghonim, Mohamed A., Pyakurel, Kusma, Ibba, Salome V., Wang, Jeffrey, Rodriguez, Paulo, Al-Khami, Amir A., Lammi, Matthew R., Kim, Hogyoung, Zea, Arnold H., Davis, Christian, Okpechi, Samuel, Wyczechowska, Dorota, Al-Ghareeb, Kamel, Mansy, Moselhy S., Ochoa, Augusto, Naura, Amarjit S., Boulares, A. Hamid
Publicado 2015

ApoE deficiency promotes colon inflammation and enhances the inflammatory potential of oxidized-LDL and TNF-α in primary colon epithelial cells

por El-Bahrawy, Ali H., Tarhuni, Abdelmetalab, Kim, Hogyoung, Subramaniam, Venkat, Benslimane, Ilyes, Elmajeed, Zakaria Y. Abd, Okpechi, Samuel C., Ghonim, Mohamed A., Hemeida, Ramadan A.M., Abo-yousef, Amira M., El-Sherbiny, Gamal A., Abdel-Raheem, Ihab T., Kim, Jong, Naura, Amarjit S., Boulares, A. Hamid
Publicado 2016

Correction: ApoE deficiency promotes colon inflammation and enhances the inflammatory potential of oxidized-LDL and TNF-α in primary colon epithelial cells

por El-Bahrawy, Ali H., Tarhuni, Abdelmetalab, Kim, Hogyoung, Subramaniam, Venkat, Benslimane, Ilyes, Elmageed, Zakaria Y. Abd, Okpechi, Samuel C., Ghonim, Mohamed A., Hemeida, Ramadan A.M., Abo-yousef, Amira M., El-Sherbiny, Gamal A., Abdel-Raheem, Ihab T., Kim, Jong, Naura, Amarjit S., Boulares, A. Hamid
Publicado 2016