The role of haploinsufficiency of RPS14 and p53 activation in the molecular pathogenesis of the 5q- syndrome

por Boultwood, Jacqueline
Publicado 2011

Recent Advances in the 5q- Syndrome

por Pellagatti, Andrea, Boultwood, Jacqueline
Publicado 2015

The impact of spliceosome mutations in MDS

por Boultwood, Jacqueline, Pellagatti, Andrea
Publicado 2019

CSNK1A1 mutations and gene expression analysis in myelodysplastic syndromes with del(5q)

por Bello, Erica, Pellagatti, Andrea, Shaw, Jacqueline, Mecucci, Cristina, Kušec, Rajko, Killick, Sally, Giagounidis, Aristoteles, Raynaud, Sophie, Calasanz, María J., Fenaux, Pierre, Boultwood, Jacqueline
Publicado 2015

Expression of microRNAs in diffuse large B cell lymphoma is associated with immunophenotype, survival and transformation from follicular lymphoma

por Lawrie, Charles H, Chi, Jianxiang, Taylor, Stephen, Tramonti, Daniela, Ballabio, Erica, Palazzo, Stefano, Saunders, Nigel J, Pezzella, Francesco, Boultwood, Jacqueline, Wainscoat, James S, Hatton, Christian S R
Publicado 2009

Meta-Analysis of Microarray Studies Reveals a Novel Hematopoietic Progenitor Cell Signature and Demonstrates Feasibility of Inter-Platform Data Integration

por Sohal, Davendra, Yeatts, Andrew, Ye, Kenny, Pellagatti, Andrea, Zhou, Li, Pahanish, Perry, Mo, Yongkai, Bhagat, Tushar, Mariadason, John, Boultwood, Jacqueline, Melnick, Ari, Greally, John, Verma, Amit
Publicado 2008

Haploinsufficiency of RPS14 in 5q− syndrome is associated with deregulation of ribosomal- and translation-related genes

por Pellagatti, Andrea, Hellström-Lindberg, Eva, Giagounidis, Aristoteles, Perry, Janet, Malcovati, Luca, Della Porta, Matteo G, Jädersten, Martin, Killick, Sally, Fidler, Carrie, Cazzola, Mario, Wainscoat, James S, Boultwood, Jacqueline
Publicado 2008

Genomic Imbalances Are Confined to Non-Proliferating Cells in Paediatric Patients with Acute Myeloid Leukaemia and a Normal or Incomplete Karyotype

por Ballabio, Erica, Regan, Regina, Garimberti, Elisa, Harbott, Jochen, Bradtke, Jutta, Teigler-Schlegel, Andrea, Biondi, Andrea, Cazzaniga, Giovanni, Giudici, Giovanni, Wainscoat, James S., Boultwood, Jacqueline, Bridger, Joanna M., Knight, Samantha J. L., Tosi, Sabrina
Publicado 2011

MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival

por Chi, Jianxiang, Ballabio, Erica, Chen, Xiao-He, Kušec, Rajko, Taylor, Steve, Hay, Deborah, Tramonti, Daniela, Saunders, Nigel J, Littlewood, Timothy, Pezzella, Francesco, Boultwood, Jacqueline, Wainscoat, James S, Hatton, Christian SR, Lawrie, Charles H
Publicado 2011

ASXL1 mutation correction by CRISPR/Cas9 restores gene function in leukemia cells and increases survival in mouse xenografts

por Valletta, Simona, Dolatshad, Hamid, Bartenstein, Matthias, Yip, Bon Ham, Bello, Erica, Gordon, Shanisha, Yu, Yiting, Shaw, Jacqueline, Roy, Swagata, Scifo, Laura, Schuh, Anna, Pellagatti, Andrea, Fulga, Tudor A., Verma, Amit, Boultwood, Jacqueline
Publicado 2015

PRPF8 Defects Cause Missplicing in Myeloid Malignancies

por Kurtovic-Kozaric, Amina, Przychodzen, Bartlomiej, Singh, Jarnail, Konarska, Maria M., Clemente, Michael J., Otrock, Zaher K., Nakashima, Meghan, Hsi, Eric D., Yoshida, Kenichi, Ogawa, Seishi, Boultwood, Jacqueline, Maciejewski, Jaroslaw P., Padgett, Richard A., Makishima, Hideki
Publicado 2014

The Role of the Iron Transporter ABCB7 in Refractory Anemia with Ring Sideroblasts

por Boultwood, Jacqueline, Pellagatti, Andrea, Nikpour, Maryam, Pushkaran, Beena, Fidler, Carrie, Cattan, Helen, Littlewood, Tim J., Malcovati, Luca, Della Porta, Matteo G., Jädersten, Martin, Killick, Sally, Giagounidis, Aristoteles, Bowen, David, Hellström-Lindberg, Eva, Cazzola, Mario, Wainscoat, James S.
Publicado 2008

Progression in patients with low- and intermediate-1-risk del(5q) myelodysplastic syndromes is predicted by a limited subset of mutations

por Scharenberg, Christian, Giai, Valentina, Pellagatti, Andrea, Saft, Leonie, Dimitriou, Marios, Jansson, Monika, Jädersten, Martin, Grandien, Alf, Douagi, Iyadh, Neuberg, Donna S., LeBlanc, Katarina, Boultwood, Jacqueline, Karimi, Mohsen, Jacobsen, Sten Eirik W., Woll, Petter S., Hellström-Lindberg, Eva
Publicado 2017

Mutation Patterns of 16 Genes in Primary and Secondary Acute Myeloid Leukemia (AML) with Normal Cytogenetics

por Fernandez-Mercado, Marta, Yip, Bon Ham, Pellagatti, Andrea, Davies, Carwyn, Larrayoz, María José, Kondo, Toshinori, Pérez, Cristina, Killick, Sally, McDonald, Emma-Jane, Odero, María Dolores, Agirre, Xabier, Prósper, Felipe, Calasanz, María José, Wainscoat, James S., Boultwood, Jacqueline
Publicado 2012

Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes

por Gerstung, Moritz, Pellagatti, Andrea, Malcovati, Luca, Giagounidis, Aristoteles, Porta, Matteo G Della, Jädersten, Martin, Dolatshad, Hamid, Verma, Amit, Cross, Nicholas C. P., Vyas, Paresh, Killick, Sally, Hellström-Lindberg, Eva, Cazzola, Mario, Papaemmanuil, Elli, Campbell, Peter J., Boultwood, Jacqueline
Publicado 2015

PRR14L mutations are associated with chromosome 22 acquired uniparental disomy, age related clonal hematopoiesis and myeloid neoplasia

por Chase, Andrew, Pellagatti, Andrea, Singh, Shalini, Score, Joannah, Tapper, William J., Lin, Feng, Hoade, Yvette, Bryant, Catherine, Trim, Nicola, Yip, Bon Ham, Zoi, Katerina, Rasi, Chiara, Forsberg, Lars A., Dumanski, Jan P., Boultwood, Jacqueline, Cross, Nicholas C. P.
Publicado 2018

A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q(−) syndrome

por Barlow, Jillian L., Drynan, Lesley F., Hewett, Duncan R., Holmes, Luke R., Lorenzo-Abalde, Silvia, Lane, Alison L., Jolin, Helen E., Pannell, Richard, Middleton, Angela J., Wong, See Heng, Warren, Alan J, Wainscoat, James S., Boultwood, Jacqueline, McKenzie, Andrew N.J.
Publicado 2009

A miRNA screening identifies miR-192-5p as associated with response to azacitidine and lenalidomide therapy in myelodysplastic syndromes

por Mongiorgi, Sara, De Stefano, Alessia, Ratti, Stefano, Indio, Valentina, Astolfi, Annalisa, Casalin, Irene, Pellagatti, Andrea, Paolini, Stefania, Parisi, Sarah, Cavo, Michele, Pession, Andrea, McCubrey, James A., Suh, Pann-Ghill, Manzoli, Lucia, Boultwood, Jacqueline, Finelli, Carlo, Cocco, Lucio, Follo, Matilde Y.
Publicado 2023

TET2 Mutations Are Associated with Specific 5-Methylcytosine and 5-Hydroxymethylcytosine Profiles in Patients with Chronic Myelomonocytic Leukemia

por Pérez, Cristina, Martínez-Calle, Nicolas, Martín-Subero, José Ignacio, Segura, Victor, Delabesse, Eric, Fernandez-Mercado, Marta, Garate, Leire, Alvarez, Sara, Rifon, José, Varea, Sara, Boultwood, Jacqueline, Wainscoat, James S., Cigudosa, Juan Cruz, Calasanz, María José, Cross, Nicholas C. P., Prósper, Felipe, Agirre, Xabier
Publicado 2012

Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q

por Adema, Vera, Palomo, Laura, Walter, Wencke, Mallo, Mar, Hutter, Stephan, La Framboise, Thomas, Arenillas, Leonor, Meggendorfer, Manja, Radivoyevitch, Tomas, Xicoy, Blanca, Pellagatti, Andrea, Haferlach, Claudia, Boultwood, Jacqueline, Kern, Wolfgang, Visconte, Valeria, Sekeres, Mikkael, Barnard, John, Haferlach, Torsten, Solé, Francesc, Maciejewski, Jaroslaw P.
Publicado 2022