P331: THE ONCOGENIC TRANSCRIPTION FACTOR TCF3::HLF MARKS A DISTINCT ENHANCER-PROMOTER INTERACTION NETWORK IN T(17;19) POSITIVE CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA

por Priebe, Valdemar, Drakul, Aneta, Zeyen, Stefan, Bornhauser, Beat, Santoro, Raffaella, Bourquin, Jean-Pierre
Publicado 2023

Rapid Generation of Leukemogenic Chromosomal Translocations in Vivo Using CRISPR/Cas9

por Huang, Yun, Marovca, Blerim, Dettwiler, Susanne, Bode, Peter Karl, Bornhauser, Beat, Bourquin, Jean-Pierre
Publicado 2020

High Immunoproteasome Activity and sXBP1 in Pediatric Precursor B-ALL Predicts Sensitivity towards Proteasome Inhibitors

por Besse, Lenka, Besse, Andrej, Kraus, Marianne, Maurits, Elmer, Overkleeft, Herman S., Bornhauser, Beat, Bourquin, Jean-Pierre, Driessen, Christoph
Publicado 2021

Targeting the 5T4 oncofetal glycoprotein with an antibody drug conjugate (A1mcMMAF) improves survival in patient-derived xenograft models of acute lymphoblastic leukemia

por McGinn, Owen J., Krishnan, Shekhar, Bourquin, Jean-Pierre, Sapra, Puja, Dempsey, Clare, Saha, Vaskar, Stern, Peter L.
Publicado 2017

Venetoclax and Bortezomib in Relapsed/Refractory Early T-Cell Precursor Acute Lymphoblastic Leukemia

por La Starza, Roberta, Cambò, Benedetta, Pierini, Antonio, Bornhauser, Beat, Montanaro, Anna, Bourquin, Jean-Pierre, Mecucci, Cristina, Roti, Giovanni
Publicado 2019

Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7

por McComb, Scott, Chan, Pik Ki, Guinot, Anna, Hartmannsdottir, Holmfridur, Jenni, Silvia, Dobay, Maria Pamela, Bourquin, Jean-Pierre, Bornhauser, Beat C.
Publicado 2019

Successes and challenges in the treatment of pediatric acute myeloid leukemia: a retrospective analysis of the AML-BFM trials from 1987 to 2012

por Rasche, Mareike, Zimmermann, Martin, Borschel, Lisa, Bourquin, Jean-Pierre, Dworzak, Michael, Klingebiel, Thomas, Lehrnbecher, Thomas, Creutzig, Ursula, Klusmann, Jan-Henning, Reinhardt, Dirk
Publicado 2018

Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support

por Boutter, Jeannette, Huang, Yun, Marovca, Blerim, Vonderheit, Andreas, Grotzer, Michael A., Eckert, Cornelia, Cario, Gunnar, Wollscheid, Bernd, Horvath, Peter, Bornhauser, Beat C., Bourquin, Jean-Pierre
Publicado 2014

Gemtuzumab ozogamicin in children with relapsed or refractory acute myeloid leukemia: a report by Berlin-Frankfurt-Münster study group

por Niktoreh, Naghmeh, Lerius, Beate, Zimmermann, Martin, Gruhn, Bernd, Escherich, Gabriele, Bourquin, Jean-Pierre, Dworzak, Michael, Sramkova, Lucie, Rossig, Claudia, Creutzig, Ursula, Reinhardt, Dirk, Rasche, Mareike
Publicado 2019

Blinatumomab in pediatric patients with relapsed/refractory acute lymphoblastic leukemia: results of the RIALTO trial, an expanded access study

por Locatelli, Franco, Zugmaier, Gerhard, Mergen, Noemi, Bader, Peter, Jeha, Sima, Schlegel, Paul-Gerhardt, Bourquin, Jean-Pierre, Handgretinger, Rupert, Brethon, Benoit, Rossig, Claudia, Chen-Santel, Christiane
Publicado 2020

Author Correction: Blinatumomab in pediatric patients with relapsed/refractory acute lymphoblastic leukemia: results of the RIALTO trial, an expanded access study

por Locatelli, Franco, Zugmaier, Gerhard, Mergen, Noemi, Bader, Peter, Jeha, Sima, Schlegel, Paul-Gerhardt, Bourquin, Jean-Pierre, Handgretinger, Rupert, Brethon, Benoit, Rossig, Claudia, Chen-Santel, Christiane
Publicado 2021

Correction: Blinatumomab in pediatric patients with relapsed/refractory acute lymphoblastic leukemia: results of the RIALTO trial, an expanded access study

por Locatelli, Franco, Zugmaier, Gerhard, Mergen, Noemi, Bader, Peter, Jeha, Sima, Schlegel, Paul-Gerhardt, Bourquin, Jean-Pierre, Handgretinger, Rupert, Brethon, Benoit, Rossig, Claudia, Chen-Santel, Christiane
Publicado 2021

P316: PRIORITIZING PRECISION MEDICINES IN PEDIATRIC BLOOD CANCER: EXPERIENCE OF THE DUTCH INDIVIDUALIZED THERAPY (ITHER) STUDY’S MOLECULAR TUMOR BOARD

por Boer, Judith M., Ilan, Uri, Hoen, Babette D.J., Boeree, Aurelie, Langenberg, Karin P.S., Koster, Jan, Bourquin, Jean-Pierre, Molenaar, Jan J., Goemans, Bianca, den Boer, Monique L., Zwaan, Michel
Publicado 2023

Blinatumomab in pediatric relapsed/refractory B-cell acute lymphoblastic leukemia: RIALTO expanded access study final analysis

por Locatelli, Franco, Zugmaier, Gerhard, Mergen, Noemi, Bader, Peter, Jeha, Sima, Schlegel, Paul-Gerhardt, Bourquin, Jean-Pierre, Handgretinger, Rupert, Brethon, Benoit, Rössig, Claudia, Kormany, William N., Viswagnachar, Puneeth, Chen-Santel, Christiane
Publicado 2022

Other (Non-CNS/Testicular) Extramedullary Localizations of Childhood Relapsed Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma—A Report from the ALL-REZ Study Group

por Lissat, Andrej, van Schewick, Claudia, Steffen, Ingo G., Arakawa, Ayumu, Bourquin, Jean-Pierre, Burkhardt, Birgit, Henze, Guenter, Mann, Georg, Peters, Christina, Sramkova, Lucie, Eckert, Cornelia, von Stackelberg, Arend, Chen-Santel, Christiane
Publicado 2021

Frequency and prognostic impact of ZEB2 H1038 and Q1072 mutations in childhood B-other acute lymphoblastic leukemia

por Zaliova, Marketa, Potuckova, Eliska, Lukes, Julius, Winkowska, Lucie, Starkova, Julia, Janotova, Iveta, Sramkova, Lucie, Stary, Jan, Zuna, Jan, Stanulla, Martin, Zimmermann, Martin, Bornhauser, Beat, Bourquin, Jean-Pierre, Eckert, Cornelia, Cario, Gunnar, Trka, Jan
Publicado 2020

Down syndrome and leukemia: from basic mechanisms to clinical advances

por Baruchel, André, Bourquin, Jean-Pierre, Crispino, John, Cuartero, Sergi, Hasle, Henrik, Hitzler, Johann, Klusmann, Jan-Henning, Izraeli, Shai, Lane, Andrew A., Malinge, Sébastien, Rabin, Karen R., Roberts, Irene, Ryeom, Sandra, Tasian, Sarah K., Wagenblast, Elvin
Publicado 2023

Molecular complete remission following combination treatment of daratumumab and venetoclax in an adolescent with relapsed mixed phenotype acute leukemia

por Stanulla, Martin, Schewe, Denis M., Bornhauser, Beat, Bourquin, Jean-Pierre, Eckert, Cornelia, Eberl, Wolfgang, Wolf, Saskia, Wolf, Julian, Vogiatzi, Fotini, Bergmann, Anke K., Cario, Gunnar, Beier, Rita, Sauer, Martin, Kratz, Christian P., Maecker-Kolhoff, Britta
Publicado 2023

Successful Salvage Chemotherapy with FOLFIRINOX for Recurrent Mixed Acinar Cell Carcinoma and Ductal Adenocarcinoma of the Pancreas in an Adolescent Patient

por Pfrommer, Sarah, Weber, Achim, Dutkowski, Philipp, Schäfer, Niklaus G., Müllhaupt, Beat, Bourquin, Jean-Pierre, Breitenstein, Stefan, Pestalozzi, Bernhard C., Stenner, Frank, Renner, Christoph, D'Addario, Giannicola, Graf, Hans-Jörg, Knuth, Alexander, Clavien, Pierre-Alain, Samaras, Panagiotis
Publicado 2013

COVID-19 – Impact on Childhood Haematology Patients

por Wolfs, Tom F.W., Attarbaschi, Andishe, Balduzzi, Adriana, Bernardo, Maria Ester, Bomken, Simon, Borkhardt, Arndt, Bourquin, Jean-Pierre, Dufour, Carlo, Gennery, Andrew, Grainger, John, Hasle, Henrik, Hrusak, Ondrej, Izraeli, Shai, Mechinaud, Francoise, Trka, Jan, Vormoor, Josef
Publicado 2020