The dark side of HDAC inhibition in ALS

por Boutillier, Anne-Laurence, Tzeplaeff, Laura, Dupuis, Luc
Publicado 2019

Altered enhancer transcription underlies Huntington’s disease striatal transcriptional signature

por Le Gras, Stéphanie, Keime, Céline, Anthony, Anne, Lotz, Caroline, De Longprez, Lucie, Brouillet, Emmanuel, Cassel, Jean-Christophe, Boutillier, Anne-Laurence, Merienne, Karine
Publicado 2017

Detection of Histone Acetylation Levels in the Dorsal Hippocampus Reveals Early Tagging on Specific Residues of H2B and H4 Histones in Response to Learning

por Bousiges, Olivier, Neidl, Romain, Majchrzak, Monique, Muller, Marc-Antoine, Barbelivien, Alexandra, Pereira de Vasconcelos, Anne, Schneider, Anne, Loeffler, Jean-Philippe, Cassel, Jean-Christophe, Boutillier, Anne-Laurence
Publicado 2013

A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis

por Palamiuc, Lavinia, Schlagowski, Anna, Ngo, Shyuan T, Vernay, Aurelia, Dirrig-Grosch, Sylvie, Henriques, Alexandre, Boutillier, Anne-Laurence, Zoll, Joffrey, Echaniz-Laguna, Andoni, Loeffler, Jean-Philippe, René, Frédérique
Publicado 2015

Deficiency of the Circadian Clock Gene Bmal1 Reduces Microglial Immunometabolism

por Wang, Xiao-Lan, Wolff, Samantha E. C., Korpel, Nikita, Milanova, Irina, Sandu, Cristina, Rensen, Patrick C. N., Kooijman, Sander, Cassel, Jean-Christophe, Kalsbeek, Andries, Boutillier, Anne-Laurence, Yi, Chun-Xia
Publicado 2020

Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process

por Mimouni, Nour El Houda, Paiva, Isabel, Barbotin, Anne-Laure, Timzoura, Fatima Ezzahra, Plassard, Damien, Le Gras, Stephanie, Ternier, Gaetan, Pigny, Pascal, Catteau-Jonard, Sophie, Simon, Virginie, Prevot, Vincent, Boutillier, Anne-Laurence, Giacobini, Paolo
Publicado 2021

Age-related and disease locus-specific mechanisms contribute to early remodelling of chromatin structure in Huntington’s disease mice

por Alcalá-Vida, Rafael, Seguin, Jonathan, Lotz, Caroline, Molitor, Anne M., Irastorza-Azcarate, Ibai, Awada, Ali, Karasu, Nezih, Bombardier, Aurélie, Cosquer, Brigitte, Skarmeta, Jose Luis Gomez, Cassel, Jean-Christophe, Boutillier, Anne-Laurence, Sexton, Thomas, Merienne, Karine
Publicado 2021

The CBP KIX domain regulates long-term memory and circadian activity

por Chatterjee, Snehajyoti, Angelakos, Christopher C., Bahl, Ethan, Hawk, Joshua D., Gaine, Marie E., Poplawski, Shane G., Schneider-Anthony, Anne, Yadav, Manish, Porcari, Giulia S., Cassel, Jean-Christophe, Giese, K. Peter, Michaelson, Jacob J., Lyons, Lisa C., Boutillier, Anne-Laurence, Abel, Ted
Publicado 2020

Microglia-specific knock-down of Bmal1 improves memory and protects mice from high fat diet-induced obesity

por Wang, Xiao-Lan, Kooijman, Sander, Gao, Yuanqing, Tzeplaeff, Laura, Cosquer, Brigitte, Milanova, Irina, Wolff, Samantha E. C., Korpel, Nikita, Champy, Marie-France, Petit-Demoulière, Benoit, Goncalves Da Cruz, Isabelle, Sorg-Guss, Tania, Rensen, Patrick C. N., Cassel, Jean-Christophe, Kalsbeek, Andries, Boutillier, Anne-Laurence, Yi, Chun-Xia
Publicado 2021

Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator

por Chatterjee, Snehajyoti, Cassel, Raphaelle, Schneider‐Anthony, Anne, Merienne, Karine, Cosquer, Brigitte, Tzeplaeff, Laura, Halder Sinha, Sarmistha, Kumar, Manoj, Chaturbedy, Piyush, Eswaramoorthy, Muthusamy, Le Gras, Stéphanie, Keime, Céline, Bousiges, Olivier, Dutar, Patrick, Petsophonsakul, Petnoi, Rampon, Claire, Cassel, Jean‐Christophe, Buée, Luc, Blum, David, Kundu, Tapas K, Boutillier, Anne‐Laurence
Publicado 2018

FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis

por Picchiarelli, Gina, Demestre, Maria, Zuko, Amila, Been, Marije, Higelin, Julia, Dieterlé, Stéphane, Goy, Marc-Antoine, Mallik, Moushami, Sellier, Chantal, Scekic-Zahirovic, Jelena, Zhang, Li, Rosenbohm, Angela, Sijlmans, Céline, Aly, Amr, Mersmann, Sina, Sanjuan-Ruiz, Inmaculada, Hübers, Annemarie, Messaddeq, Nadia, Wagner, Marina, van Bakel, Nick, Boutillier, Anne-Laurence, Ludolph, Albert, Lagier-Tourenne, Clotilde, Boeckers, Tobias M., Dupuis, Luc, Storkebaum, Erik
Publicado 2019

Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A(2A) receptor

por Carvalho, Kevin, Faivre, Emilie, Pietrowski, Marie J, Marques, Xavier, Gomez-Murcia, Victoria, Deleau, Aude, Huin, Vincent, Hansen, Jan N, Kozlov, Stanislav, Danis, Clément, Temido-Ferreira, Mariana, Coelho, Joana E, Mériaux, Céline, Eddarkaoui, Sabiha, Gras, Stéphanie Le, Dumoulin, Mélanie, Cellai, Lucrezia, Landrieu, Isabelle, Chern, Yijuang, Hamdane, Malika, Buée, Luc, Boutillier, Anne-Laurence, Levi, Sabine, Halle, Annett, Lopes, Luisa V, Blum, David
Publicado 2019

Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects

por Scekic-Zahirovic, Jelena, Sanjuan-Ruiz, Inmaculada, Kan, Vanessa, Megat, Salim, De Rossi, Pierre, Dieterlé, Stéphane, Cassel, Raphaelle, Jamet, Marguerite, Kessler, Pascal, Wiesner, Diana, Tzeplaeff, Laura, Demais, Valérie, Sahadevan, Sonu, Hembach, Katharina M., Muller, Hans-Peter, Picchiarelli, Gina, Mishra, Nibha, Antonucci, Stefano, Dirrig-Grosch, Sylvie, Kassubek, Jan, Rasche, Volker, Ludolph, Albert, Boutillier, Anne-Laurence, Roselli, Francesco, Polymenidou, Magdalini, Lagier-Tourenne, Clotilde, Liebscher, Sabine, Dupuis, Luc
Publicado 2021

Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription

por Paiva, Isabel, Cellai, Lucrezia, Meriaux, Céline, Poncelet, Lauranne, Nebie, Ouada, Saliou, Jean-Michel, Lacoste, Anne-Sophie, Papegaey, Anthony, Drobecq, Hervé, Le Gras, Stéphanie, Schneider, Marion, Malik, Enas M., Müller, Christa E., Faivre, Emilie, Carvalho, Kevin, Gomez-Murcia, Victoria, Vieau, Didier, Thiroux, Bryan, Eddarkaoui, Sabiha, Lebouvier, Thibaud, Schueller, Estelle, Tzeplaeff, Laura, Grgurina, Iris, Seguin, Jonathan, Stauber, Jonathan, Lopes, Luisa V., Buée, Luc, Buée-Scherrer, Valérie, Cunha, Rodrigo A., Ait-Belkacem, Rima, Sergeant, Nicolas, Annicotte, Jean-Sébastien, Boutillier, Anne-Laurence, Blum, David
Publicado 2022