Fanconi anemia pathway regulation by FANCI in prostate cancer

por Kaljunen, Heidi, Taavitsainen, Sinja, Kaarijärvi, Roosa, Takala, Eerika, Paakinaho, Ville, Nykter, Matti, Bova, G. Steven, Ketola, Kirsi
Publicado 2023

The expression of AURKA is androgen regulated in castration-resistant prostate cancer

por Kivinummi, Kati, Urbanucci, Alfonso, Leinonen, Katri, Tammela, Teuvo L. J., Annala, Matti, Isaacs, William B., Bova, G. Steven, Nykter, Matti, Visakorpi, Tapio
Publicado 2017

Integrated clinical, whole-genome, and transcriptome analysis of multisampled lethal metastatic prostate cancer

por Bova, G. Steven, Kallio, Heini M.L., Annala, Matti, Kivinummi, Kati, Högnäs, Gunilla, Häyrynen, Sergei, Rantapero, Tommi, Kivinen, Virpi, Isaacs, William B., Tolonen, Teemu, Nykter, Matti, Visakorpi, Tapio
Publicado 2016

Subclone Eradication Analysis Identifies Targets for Enhanced Cancer Therapy and Reveals L1 Retrotransposition as a Dynamic Source of Cancer Heterogeneity

por Ketola, Kirsi, Kaljunen, Heidi, Taavitsainen, Sinja, Kaarijärvi, Roosa, Järvelä, Emmi, Rodríguez-Martín, Bernardo, Haase, Kerstin, Woodcock, Dan J., Tubio, Jose, Wedge, David C., Nykter, Matti, Bova, G. Steven
Publicado 2021

Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer

por Sjöblom, Liisa, Saramäki, Outi, Annala, Matti, Leinonen, Katri, Nättinen, Janika, Tolonen, Teemu, Wahlfors, Tiina, Nykter, Matti, Bova, G. Steven, Schleutker, Johanna, Tammela, Teuvo L. J., Lilja, Hans, Visakorpi, Tapio
Publicado 2016

Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases

por Kallio, Heini M. L., Hieta, Reija, Latonen, Leena, Brofeldt, Anniina, Annala, Matti, Kivinummi, Kati, Tammela, Teuvo L., Nykter, Matti, Isaacs, William B., Lilja, Hans G., Bova, G. Steven, Visakorpi, Tapio
Publicado 2018

Identification of long noncoding RNAs with aberrant expression in prostate cancer metastases

por Sattari, Mina, Kohvakka, Annika, Moradi, Elaheh, Rauhala, Hanna, Urhonen, Henna, Isaacs, William B, Nykter, Matti, Murtola, Teemu J, Tammela, Teuvo L J, Latonen, Leena, Bova, G Steven, Kesseli, Juha, Visakorpi, Tapio
Publicado 2023

Proteomic characterization of primary and metastatic prostate cancer reveals reduced proteinase activity in aggressive tumors

por Li, Qing Kay, Chen, Jing, Hu, Yingwei, Höti, Naseruddin, Lih, Tung-Shing Mamie, Thomas, Stefani N., Chen, Li, Roy, Sujayita, Meeker, Alan, Shah, Punit, Chen, Lijun, Bova, G. Steven, Zhang, Bai, Zhang, Hui
Publicado 2021

Androgen-induced TOP2B mediated double strand breaks and prostate cancer gene rearrangements

por Haffner, Michael C., Aryee, Martin J., Toubaji, Antoun, Esopi, David M., Albadine, Roula, Gurel, Bora, Isaacs, William B., Bova, G. Steven, Liu, Wennuan, Xu, Jianfeng, Meeker, Alan K., Netto, George, De Marzo, Angelo M., Nelson, William G., Yegnasubramanian, Srinivasan
Publicado 2010

Copy Number Analysis Indicates Monoclonal Origin of Lethal Metastatic Prostate Cancer

por Liu, Wennuan, Laitinen, Sari, Khan, Sofia, Vihinen, Mauno, Kowalski, Jeanne, Yu, Guoqiang, Chen, Li, Ewing, Charles M., Eisenberger, Mario A., Carducci, Michael A., Nelson, William G., Yegnasubramanian, Srinivasan, Luo, Jun, Wang, Yue, Xu, Jianfeng, Isaacs, William B., Visakorpi, Tapio, Bova, G. Steven
Publicado 2009

Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine

por Nurminen, Anssi, Jaatinen, Serafiina, Taavitsainen, Sinja, Högnäs, Gunilla, Lesluyes, Tom, Ansari-Pour, Naser, Tolonen, Teemu, Haase, Kerstin, Koskenalho, Antti, Kankainen, Matti, Jasu, Juho, Rauhala, Hanna, Kesäniemi, Jenni, Nikupaavola, Tiia, Kujala, Paula, Rinta-Kiikka, Irina, Riikonen, Jarno, Kaipia, Antti, Murtola, Teemu, Tammela, Teuvo L., Visakorpi, Tapio, Nykter, Matti, Wedge, David C., Van Loo, Peter, Bova, G. Steven
Publicado 2023

The architecture of clonal expansions in morphologically normal tissue from cancerous and non-cancerous prostates

por Buhigas, Claudia, Warren, Anne Y., Leung, Wing-Kit, Whitaker, Hayley C., Luxton, Hayley J., Hawkins, Steve, Kay, Jonathan, Butler, Adam, Xu, Yaobo, Woodcock, Dan J., Merson, Sue, Frame, Fiona M., Sahli, Atef, Abascal, Federico, Martincorena, Iñigo, Bova, G. Steven, Foster, Christopher S., Campbell, Peter, Maitland, Norman J., Neal, David E., Massie, Charlie E., Lynch, Andy G., Eeles, Rosalind A., Cooper, Colin S., Wedge, David C., Brewer, Daniel S.
Publicado 2022

Combined Longitudinal Clinical and Autopsy Phenomic Assessment in Lethal Metastatic Prostate Cancer: Recommendations for Advancing Precision Medicine

por Jasu, Juho, Tolonen, Teemu, Antonarakis, Emmanuel S., Beltran, Himisha, Halabi, Susan, Eisenberger, Mario A., Carducci, Michael A., Loriot, Yohann, Van der Eecken, Kim, Lolkema, Martijn, Ryan, Charles J., Taavitsainen, Sinja, Gillessen, Silke, Högnäs, Gunilla, Talvitie, Timo, Taylor, Robert J., Koskenalho, Antti, Ost, Piet, Murtola, Teemu J., Rinta-Kiikka, Irina, Tammela, Teuvo, Auvinen, Anssi, Kujala, Paula, Smith, Thomas J., Kellokumpu-Lehtinen, Pirkko-Liisa, Isaacs, William B., Nykter, Matti, Kesseli, Juha, Bova, G. Steven
Publicado 2021

The Evolutionary History of Lethal Metastatic Prostate Cancer

por Gundem, Gunes, Van Loo, Peter, Kremeyer, Barbara, Alexandrov, Ludmil B., Tubio, Jose M.C., Papaemmanuil, Elli, Brewer, Daniel S., Kallio, Heini M.L., Högnäs, Gunilla, Annala, Matti, Kivinummi, Kati, Goody, Victoria, Latimer, Calli, O’Meara, Sarah, Dawson, Kevin J., Isaacs, William, Emmert-Buck, Michael R, Nykter, Matti, Foster, Christopher, Kote-Jarai, Zsofia, Easton, Douglas, Whitaker, Hayley C., Neal, David E., Cooper, Colin S., Eeles, Rosalind A., Visakorpi, Tapio, Campbell, Peter J., McDermott, Ultan, Wedge, David C., Bova, G. Steven
Publicado 2015

The Movember Global Action Plan 1 (GAP1): Unique Prostate Cancer Tissue Microarray Resource

por Ouellet, Véronique, Erickson, Andrew, Wiley, Kathy, Morrissey, Colm, Berge, Viktor, Moreno, Carlos S., Tasken, Kristin Austlid, Trudel, Dominique, True, Lawrence D., Lewis, Michael S., Svindland, Aud, Ertunc, Onur, Vidal, Igor Damasceno, Osunkoya, Adeboye O., Jones, Tracy, Bova, G. Steven, Lamminen, Tarja, Achtman, Ariel H., Buzza, Mark, Kouspou, Michelle M., Bigler, Steven A., Zhou, Xinchun, Freedland, Stephen J., Mes-Masson, Anne-Marie, Garraway, Isla P., Trock, Bruce J., Taimen, Pekka, Saad, Fred, Mirtti, Tuomas, Knudsen, Beatrice S., De Marzo, Angelo M.
Publicado 2022

Mutational signatures of ionizing radiation in second malignancies

por Behjati, Sam, Gundem, Gunes, Wedge, David C., Roberts, Nicola D., Tarpey, Patrick S., Cooke, Susanna L., Van Loo, Peter, Alexandrov, Ludmil B., Ramakrishna, Manasa, Davies, Helen, Nik-Zainal, Serena, Hardy, Claire, Latimer, Calli, Raine, Keiran M., Stebbings, Lucy, Menzies, Andy, Jones, David, Shepherd, Rebecca, Butler, Adam P., Teague, Jon W., Jorgensen, Mette, Khatri, Bhavisha, Pillay, Nischalan, Shlien, Adam, Futreal, P. Andrew, Badie, Christophe, McDermott, Ultan, Bova, G. Steven, Richardson, Andrea L., Flanagan, Adrienne M., Stratton, Michael R., Campbell, Peter J.
Publicado 2016

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

por Ju, Young Seok, Alexandrov, Ludmil B, Gerstung, Moritz, Martincorena, Inigo, Nik-Zainal, Serena, Ramakrishna, Manasa, Davies, Helen R, Papaemmanuil, Elli, Gundem, Gunes, Shlien, Adam, Bolli, Niccolo, Behjati, Sam, Tarpey, Patrick S, Nangalia, Jyoti, Massie, Charles E, Butler, Adam P, Teague, Jon W, Vassiliou, George S, Green, Anthony R, Du, Ming-Qing, Unnikrishnan, Ashwin, Pimanda, John E, Teh, Bin Tean, Munshi, Nikhil, Greaves, Mel, Vyas, Paresh, El-Naggar, Adel K, Santarius, Tom, Collins, V Peter, Grundy, Richard, Taylor, Jack A, Hayes, D Neil, Malkin, David, Foster, Christopher S, Warren, Anne Y, Whitaker, Hayley C, Brewer, Daniel, Eeles, Rosalind, Cooper, Colin, Neal, David, Visakorpi, Tapio, Isaacs, William B, Bova, G Steven, Flanagan, Adrienne M, Futreal, P Andrew, Lynch, Andy G, Chinnery, Patrick F, McDermott, Ultan, Stratton, Michael R, Campbell, Peter J
Publicado 2014

Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data

por Camacho, Niedzica, Van Loo, Peter, Edwards, Sandra, Kay, Jonathan D., Matthews, Lucy, Haase, Kerstin, Clark, Jeremy, Dennis, Nening, Thomas, Sarah, Kremeyer, Barbara, Zamora, Jorge, Butler, Adam P., Gundem, Gunes, Merson, Sue, Luxton, Hayley, Hawkins, Steve, Ghori, Mohammed, Marsden, Luke, Lambert, Adam, Karaszi, Katalin, Pelvender, Gill, Massie, Charlie E., Kote-Jarai, Zsofia, Raine, Keiran, Jones, David, Howat, William J., Hazell, Steven, Livni, Naomi, Fisher, Cyril, Ogden, Christopher, Kumar, Pardeep, Thompson, Alan, Nicol, David, Mayer, Erik, Dudderidge, Tim, Yu, Yongwei, Zhang, Hongwei, Shah, Nimish C., Gnanapragasam, Vincent J., Isaacs, William, Visakorpi, Tapio, Hamdy, Freddie, Berney, Dan, Verrill, Clare, Warren, Anne Y., Wedge, David C., Lynch, Andrew G., Foster, Christopher S., Lu, Yong Jie, Bova, G. Steven, Whitaker, Hayley C., McDermott, Ultan, Neal, David E., Eeles, Rosalind, Cooper, Colin S., Brewer, Daniel S.
Publicado 2017