ARQ531: the therapy that targets multiple pathways in acute myeloid leukemia

por Hellmich, Charlotte, Bowles, Kristian, Rushworth, Stuart
Publicado 2020

The Role of PI3K Isoforms in Regulating Bone Marrow Microenvironment Signaling Focusing on Acute Myeloid Leukemia and Multiple Myeloma

por Piddock, Rachel E., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2017

Acute Myeloid Leukaemia Drives Metabolic Changes in the Bone Marrow Niche

por Maynard, Rebecca S., Hellmich, Charlotte, Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2022

Bone Marrow Senescence and the Microenvironment of Hematological Malignancies

por Hellmich, Charlotte, Moore, Jamie A., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2020

Oxidative Stress Responses and NRF2 in Human Leukaemia

por Abdul-Aziz, Amina, MacEwan, David J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2015

P1341: LC3-ASSOCIATED PHAGOCYTOSIS IS IMPAIRED IN BONE MARROW MACROPHAGES DURING AGEING LEADING TO DEFECTIVE PHAGOCYTOSIS AND ACCUMULATION OF APOPTOTIC DEBRIS WITHIN THE BONE MARRO...

por Hampton, Katherine, Hellmich, Charlotte, Maynard, Rebecca, Jibril, Aisha, Moore, Jamie, Bowles, Kristian, Rushworth, Stuart
Publicado 2023

FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism

por Rushworth, Stuart A, Zaitseva, Lyubov, Langa, Susana, Bowles, Kristian M, MacEwan, David J
Publicado 2010

P423: ACUTE MYELOID LEUKEMIA REPROGRAMS LIPID METABOLISM BY DOWNREGULATING CD36 EXPRESSION IN HEPATOCYTES.

por Maynard, Rebecca, Hampton, Katherine, Hellmich, Charlotte, Ehikioya, Martha, Fowler-Shorten, Dominic, Bowles, Kristian, Rushworth, Stuart
Publicado 2023

Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1

por Heasman, Sally-Anne, Zaitseva, Lyubov, Bowles, Kristian M., Rushworth, Stuart A., MacEwan, David J.
Publicado 2011

Mitochondrial oxidative phosphorylation in cutaneous melanoma

por Kumar, Prakrit R., Moore, Jamie A., Bowles, Kristian M., Rushworth, Stuart A., Moncrieff, Marc D.
Publicado 2020

Understanding the role of NRF2-regulated miRNAs in human malignancies

por Shah, Niraj M, Rushworth, Stuart A, Murray, Megan Y, Bowles, Kristian M, MacEwan, David J
Publicado 2013

P469: ACUTE MYELOID LEUKEMIA DRIVES BCL-2 UPREGULATION IN NON MALIGNANT HSPCS WHICH IS TARGETED BY VENETOCLAX AND CAUSES CYTOPENIA

por Fowler-Shorten, Dominic, Maynard, Rebecca, Hampton, Katherine, Ehikioya, Martha, De Silva, Ravindu, Bowles, Kristian, Rushworth, Stuart, Hellmich, Charlotte
Publicado 2023

Low estimated glomerular filtration rate and pneumonia in stroke patients: findings from a prospective stroke registry in the East of England

por Vart, Priya, Bettencourt-Silva, Joao H, Metcalf, Anthony K, Bowles, Kristian M, Potter, John F, Myint, Phyo K
Publicado 2018

P856: MULTIPLE MYELOMA DERIVED IL-6 REDUCES FATTY ACID METABOLISM IN THE LIVER BY DOWNREGULATING CD36 AND CPT1A IN HEPATOCYTES

por Egheose Ehikioya, Martha, Maynard, Rebecca, Hampton, Katherine, Hellmich, Charlotte, De Silva, Ravindu, Fowler-Shorten, Dominic, Bowles, Kristian, Rushworth, Stuart
Publicado 2023

Targeting BTK for the treatment of FLT3-ITD mutated acute myeloid leukemia

por Pillinger, Genevra, Abdul-Aziz, Amina, Zaitseva, Lyubov, Lawes, Matthew, MacEwan, David J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2015

Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML

por Zaitseva, Lyubov, Murray, Megan Y., Shafat, Manar S., Lawes, Matthew J., MacEwan, David J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2014

Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYC

por Piddock, Rachel E., Marlein, Christopher R., Abdul-Aziz, Amina, Shafat, Manar S., Auger, Martin J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2018

Venetoclax and Daratumumab combination treatment demonstrates pre-clinical efficacy in mouse models of Acute Myeloid Leukemia

por Mistry, Jayna J, Hellmich, Charlotte, Lambert, Amelia, Moore, Jamie A, Jibril, Aisha, Collins, Angela, Bowles, Kristian M, Rushworth, Stuart A
Publicado 2021

Erdheim-Chester Disease: Two cases from an ophthalmic perspective

por Brodie, James, Zhou, Sean, Makkuni, Damodar, Beadsmoore, Clare, Mukhtyar, Chetan, Saada, Janak, Bowles, Kristian M., Beigi, Bijan, Burton, Ben J.L.
Publicado 2020

P431: ACTIVATION OF MACROPHAGE STING ENHANCES PHAGOCYTOSIS OF ACUTE MYELOID LEUKAEMIA

por Maynard, Rebecca, Hellmich, Charlotte, Hampton, Katherine, Moore, Jamie, Jibril, Aisha, De Silva, Ravindu, Fowler-Shorten, Dominic, Ehikioya, Martha, Bowles, Kristian, Rushworth, Stuart
Publicado 2023