The Role of PI3K Isoforms in Regulating Bone Marrow Microenvironment Signaling Focusing on Acute Myeloid Leukemia and Multiple Myeloma

por Piddock, Rachel E., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2017

Acute Myeloid Leukaemia Drives Metabolic Changes in the Bone Marrow Niche

por Maynard, Rebecca S., Hellmich, Charlotte, Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2022

Bone Marrow Senescence and the Microenvironment of Hematological Malignancies

por Hellmich, Charlotte, Moore, Jamie A., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2020

Oxidative Stress Responses and NRF2 in Human Leukaemia

por Abdul-Aziz, Amina, MacEwan, David J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2015

FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism

por Rushworth, Stuart A, Zaitseva, Lyubov, Langa, Susana, Bowles, Kristian M, MacEwan, David J
Publicado 2010

Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1

por Heasman, Sally-Anne, Zaitseva, Lyubov, Bowles, Kristian M., Rushworth, Stuart A., MacEwan, David J.
Publicado 2011

Mitochondrial oxidative phosphorylation in cutaneous melanoma

por Kumar, Prakrit R., Moore, Jamie A., Bowles, Kristian M., Rushworth, Stuart A., Moncrieff, Marc D.
Publicado 2020

Understanding the role of NRF2-regulated miRNAs in human malignancies

por Shah, Niraj M, Rushworth, Stuart A, Murray, Megan Y, Bowles, Kristian M, MacEwan, David J
Publicado 2013

Low estimated glomerular filtration rate and pneumonia in stroke patients: findings from a prospective stroke registry in the East of England

por Vart, Priya, Bettencourt-Silva, Joao H, Metcalf, Anthony K, Bowles, Kristian M, Potter, John F, Myint, Phyo K
Publicado 2018

Targeting BTK for the treatment of FLT3-ITD mutated acute myeloid leukemia

por Pillinger, Genevra, Abdul-Aziz, Amina, Zaitseva, Lyubov, Lawes, Matthew, MacEwan, David J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2015

Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML

por Zaitseva, Lyubov, Murray, Megan Y., Shafat, Manar S., Lawes, Matthew J., MacEwan, David J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2014

Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYC

por Piddock, Rachel E., Marlein, Christopher R., Abdul-Aziz, Amina, Shafat, Manar S., Auger, Martin J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2018

Venetoclax and Daratumumab combination treatment demonstrates pre-clinical efficacy in mouse models of Acute Myeloid Leukemia

por Mistry, Jayna J, Hellmich, Charlotte, Lambert, Amelia, Moore, Jamie A, Jibril, Aisha, Collins, Angela, Bowles, Kristian M, Rushworth, Stuart A
Publicado 2021

Erdheim-Chester Disease: Two cases from an ophthalmic perspective

por Brodie, James, Zhou, Sean, Makkuni, Damodar, Beadsmoore, Clare, Mukhtyar, Chetan, Saada, Janak, Bowles, Kristian M., Beigi, Bijan, Burton, Ben J.L.
Publicado 2020

Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection

por Pillinger, Genevra, Loughran, Niamh V., Piddock, Rachel E., Shafat, Manar S., Zaitseva, Lyubov, Abdul-Aziz, Amina, Lawes, Matthew J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2016

Inflammatory Differences in Plaque Erosion and Rupture in Patients With ST‐Segment Elevation Myocardial Infarction

por Chandran, Sujay, Watkins, Johnathan, Abdul‐Aziz, Amina, Shafat, Manar, Calvert, Patrick A., Bowles, Kristian M., Flather, Marcus D., Rushworth, Stuart A., Ryding, Alisdair D.
Publicado 2017

Long-Term Factors Associated With Falls and Fractures Poststroke

por Foster, Emma J., Barlas, Raphae S., Bettencourt-Silva, Joao H., Clark, Allan B., Metcalf, Anthony K., Bowles, Kristian M., Potter, John F., Myint, Phyo K.
Publicado 2018

Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells

por Wittmann, Alexandra, Lamprinaki, Dimitra, Bowles, Kristian M., Katzenellenbogen, Ewa, Knirel, Yuriy A., Whitfield, Chris, Nishimura, Takashi, Matsumoto, Naoki, Yamamoto, Kazuo, Iwakura, Yoichiro, Saijo, Shinobu, Kawasaki, Norihito
Publicado 2016

Free fatty-acid transport via CD36 drives β-oxidation-mediated hematopoietic stem cell response to infection

por Mistry, Jayna J., Hellmich, Charlotte, Moore, Jamie A., Jibril, Aisha, Macaulay, Iain, Moreno-Gonzalez, Mar, Di Palma, Federica, Beraza, Naiara, Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2021

A History of Falls is Associated with a Significant Increase in Acute Mortality in Women after Stroke

por Foster, Emma J., Barlas, Raphae S., Wood, Adrian D., Bettencourt-Silva, Joao H., Clark, Allan B., Metcalf, Anthony K., Bowles, Kristian M., Potter, John F., Myint, Phyo K.
Publicado 2017