Why Do HIV-1 and HIV-2 Use Different Pathways to Develop AZT Resistance?

por Boyer, Paul L, Sarafianos, Stefan G, Clark, Patrick K, Arnold, Eddy, Hughes, Stephen H
Publicado 2006

4-Amino-1-hydroxy-2-oxo-1,8-naphthyridine-Containing Compounds Having High Potency against Raltegravir-Resistant Integrase Mutants of HIV-1

por Zhao, Xue Zhi, Smith, Steven J., Métifiot, Mathieu, Marchand, Christophe, Boyer, Paul L., Pommier, Yves, Hughes, Stephen H., Burke, Terrence R.
Publicado 2014

Correction to 4-Amino-1-hydroxy-2-oxo-1,8-naphthyridine-Containing Compounds Having High Potency against Raltegravir-Resistant Integrase Mutants of HIV-1

por Zhao, Xue Zhi, Smith, Steven J., Métifiot, Mathieu, Marchand, Christophe, Boyer, Paul L., Pommier, Yves, Hughes, Stephen H., Burke, Terrence R.
Publicado 2014

Two Coselected Distal Mutations in HIV-1 Reverse Transcriptase (RT) Alter Susceptibility to Nonnucleoside RT Inhibitors and Nucleoside Analogs

por Boyer, Paul L., Melody, Kevin, Smith, Steven J., Dunn, Linda L., Kline, Chris, Fischer, Douglas K., Dwivedi, Richa, Clark, Pat, Hughes, Stephen H., Ambrose, Zandrea
Publicado 2019

Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT)

por Harrison, Jerry Joe E. K., Tuske, Steve, Das, Kalyan, Ruiz, Francesc X., Bauman, Joseph D., Boyer, Paul L., DeStefano, Jeffrey J., Hughes, Stephen H., Arnold, Eddy
Publicado 2021

Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design

por Bauman, Joseph D., Das, Kalyan, Ho, William C., Baweja, Mukta, Himmel, Daniel M., Clark, Arthur D., Oren, Deena A., Boyer, Paul L., Hughes, Stephen H., Shatkin, Aaron J., Arnold, Eddy
Publicado 2008

Structural Basis for the Role of the K65R Mutation in HIV-1 Reverse Transcriptase Polymerization, Excision Antagonism, and Tenofovir Resistance

por Das, Kalyan, Bandwar, Rajiv P., White, Kirsten L., Feng, Joy Y., Sarafianos, Stefan G., Tuske, Steven, Tu, Xiongying, Clark, Arthur D., Boyer, Paul L., Hou, Xiaorong, Gaffney, Barbara L., Jones, Roger A., Miller, Michael D., Hughes, Stephen H., Arnold, Eddy
Publicado 2009