Amino Acid Transporters as Targets for Cancer Therapy: Why, Where, When, and How

por Bröer, Stefan
Publicado 2020

Amino acid homeostasis and signalling in mammalian cells and organisms

por Bröer, Stefan, Bröer, Angelika
Publicado 2017

Mice Lacking the Intestinal and Renal Neutral Amino Acid Transporter SLC6A19 Demonstrate the Relationship between Dietary Protein Intake and Amino Acid Malabsorption

por Javed, Kiran, Bröer, Stefan
Publicado 2019

Amino Acid Homeostasis in Mammalian Cells with a Focus on Amino Acid Transport

por Bröer, Stefan, Gauthier-Coles, Gregory
Publicado 2021

Disruption of Amino Acid Homeostasis by Novel ASCT2 Inhibitors Involves Multiple Targets

por Bröer, Angelika, Fairweather, Stephen, Bröer, Stefan
Publicado 2018

Inhibition of GCN2 Reveals Synergy with Cell-Cycle Regulation and Proteostasis

por Gauthier-Coles, Gregory, Rahimi, Farid, Bröer, Angelika, Bröer, Stefan
Publicado 2023

ATP11C Facilitates Phospholipid Translocation across the Plasma Membrane of All Leukocytes

por Yabas, Mehmet, Jing, Weidong, Shafik, Sarah, Bröer, Stefan, Enders, Anselm
Publicado 2016

Impact of Inhibition of Glutamine and Alanine Transport on Cerebellar Glial and Neuronal Metabolism

por Das, Abhijit, Gauthier-Coles, Gregory, Bröer, Stefan, Rae, Caroline D.
Publicado 2022

Do Amino Acid Antiporters Have Asymmetric Substrate Specificity?

por Gauthier-Coles, Gregory, Fairweather, Stephen J., Bröer, Angelika, Bröer, Stefan
Publicado 2023

Intestinal peptidases form functional complexes with the neutral amino acid transporter B(0)AT1

por Fairweather, Stephen J., Bröer, Angelika, O'Mara, Megan L., Bröer, Stefan
Publicado 2012

Expression of Glutamine Transporter Slc38a3 (SNAT3) During Acidosis is Mediated by a Different Mechanism than Tissue-Specific Expression

por Balkrishna, Sarojini, Bröer, Angelika, Welford, Scott M., Hatzoglou, Maria, Bröer, Stefan
Publicado 2014

ASCT2 (SLC1A5)-Deficient Mice Have Normal B-Cell Development, Proliferation, and Antibody Production

por Masle-Farquhar, Etienne, Bröer, Angelika, Yabas, Mehmet, Enders, Anselm, Bröer, Stefan
Publicado 2017

Development of Biomarkers for Inhibition of SLC6A19 (B(0)AT1)—A Potential Target to Treat Metabolic Disorders

por Javed, Kiran, Cheng, Qi, Carroll, Adam J., Truong, Thy T., Bröer, Stefan
Publicado 2018

PKC-Mediated Modulation of Astrocyte SNAT3 Glutamine Transporter Function at Synapses in Situ

por Dong, Wuxing, Todd, Alison C., Bröer, Angelika, Hulme, Sarah R., Bröer, Stefan, Billups, Brian
Publicado 2018

A GC-MS/Single-Cell Method to Evaluate Membrane Transporter Substrate Specificity and Signaling

por Fairweather, Stephen J., Okada, Shoko, Gauthier-Coles, Gregory, Javed, Kiran, Bröer, Angelika, Bröer, Stefan
Publicado 2021

Maternal heterozygosity of Slc6a19 causes metabolic perturbation and congenital NAD deficiency disorder in mice

por Cuny, Hartmut, Bozon, Kayleigh, Kirk, Rosemary B., Sheng, Delicia Z., Bröer, Stefan, Dunwoodie, Sally L.
Publicado 2022

Characterization of a Dopamine Transporter and Its Splice Variant Reveals Novel Features of Dopaminergic Regulation in the Honey Bee

por Zhang, Vicky, Kucharski, Robert, Landers, Courtney, Richards, Sashika N., Bröer, Stefan, Martin, Rowena E., Maleszka, Ryszard
Publicado 2019

Novel Chemical Scaffolds to Inhibit the Neutral Amino Acid Transporter B(0)AT1 (SLC6A19), a Potential Target to Treat Metabolic Diseases

por Yadav, Aditya, Shah, Nishank, Tiwari, Praveen Kumar, Javed, Kiran, Cheng, Qi, Aidhen, Indrapal Singh, Bröer, Stefan
Publicado 2020

Breakdown in membrane asymmetry regulation leads to monocyte recognition of P. falciparum-infected red blood cells

por Fraser, Merryn, Jing, Weidong, Bröer, Stefan, Kurth, Florian, Sander, Leif-Erik, Matuschewski, Kai, Maier, Alexander G.
Publicado 2021

Identification and characterization of a novel SNAT2 (SLC38A2) inhibitor reveals synergy with glucose transport inhibition in cancer cells

por Gauthier-Coles, Gregory, Bröer, Angelika, McLeod, Malcolm Donald, George, Amee J., Hannan, Ross D., Bröer, Stefan
Publicado 2022