Mechanistic Investigations of Metallo‐β‐lactamase Inhibitors: Strong Zinc Binding Is Not Required for Potent Enzyme Inhibition

por Wade, Nicola, Tehrani, Kamaleddin H. M. E., Brüchle, Nora C., van Haren, Matthijs J., Mashayekhi, Vida, Martin, Nathaniel I.
Publicado 2021

Small Molecule Carboxylates Inhibit Metallo-β-lactamases and Resensitize Carbapenem-Resistant Bacteria to Meropenem

por Tehrani, Kamaleddin H. M. E., Brüchle, Nora C., Wade, Nicola, Mashayekhi, Vida, Pesce, Diego, van Haren, Matthijs J., Martin, Nathaniel I.
Publicado 2020

Cephalosporin Prodrug Inhibitors Overcome Metallo‐β‐Lactamase Driven Antibiotic Resistance

por van Haren, Matthijs J., Tehrani, Kamaleddin H. M. E., Kotsogianni, Ioli, Wade, Nicola, Brüchle, Nora C., Mashayekhi, Vida, Martin, Nathaniel I.
Publicado 2021

Accelerated production of α2,8- and α2,9-linked polysialic acid in recombinant Escherichia coli using high cell density cultivation

por Bartling, Bastian, Brüchle, Nora C., Rehfeld, Johanna S., Boßmann, Daniel, Fiebig, Timm, Litschko, Christa, Fohrer, Jörg, Gerardy-Schahn, Rita, Scheper, Thomas, Beutel, Sascha
Publicado 2020

Novel Cephalosporin Conjugates Display Potent and Selective Inhibition of Imipenemase-Type Metallo-β-Lactamases

por Tehrani, Kamaleddin H. M. E., Wade, Nicola, Mashayekhi, Vida, Brüchle, Nora C., Jespers, Willem, Voskuil, Koen, Pesce, Diego, van Haren, Matthijs J., van Westen, Gerard J. P., Martin, Nathaniel I.
Publicado 2021

Synthetic studies with the brevicidine and laterocidine lipopeptide antibiotics including analogues with enhanced properties and in vivo efficacy

por Al Ayed, Karol, Ballantine, Ross D., Hoekstra, Michael, Bann, Samantha J., Wesseling, Charlotte M. J., Bakker, Alexander T., Zhong, Zheng, Li, Yong-Xin, Brüchle, Nora C., van der Stelt, Mario, Cochrane, Stephen A., Martin, Nathaniel I.
Publicado 2022