Human Organ Culture: Updating the Approach to Bridge the Gap from In Vitro to In Vivo in Inflammation, Cancer, and Stem Cell Biology

por Al-Lamki, Rafia S., Bradley, John R., Pober, Jordan S.
Publicado 2017

TL1-A can engage death receptor-3 and activate NF-kappa B in endothelial cells

por Wang, Jun, Al-Lamki, Rafia S, Zhu, Xinwang, Liu, Hanzhe, Pober, Jordan S, Bradley, John R
Publicado 2014

Tumor necrosis factor receptor‐2 signaling pathways promote survival of cancer stem‐like CD133(+) cells in clear cell renal carcinoma

por Bradley, John R., Wang, Jun, Pacey, Simon, Warren, Anne Y., Pober, Jordan S., Al‐Lamki, Rafia S.
Publicado 2020

SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity

por Meng, Bo, Datir, Rawlings, Choi, Jinwook, Bradley, John R., Smith, Kenneth G.C., Lee, Joo Hyeon, Gupta, Ravindra K.
Publicado 2022

Using machine learning to model older adult inpatient trajectories from electronic health records data

por Herrero-Zazo, Maria, Fitzgerald, Tomas, Taylor, Vince, Street, Helen, Chaudhry, Afzal N., Bradley, John R., Birney, Ewan, Keevil, Victoria L.
Publicado 2022

TNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-κB pathway

por Wang, Jun, Ferreira, Ricardo, Lu, Wanhua, Farrow, Samatha, Downes, Kate, Jermutus, Lutz, Minter, Ralph, Al-Lamki, Rafia S., Pober, Jordan S., Bradley, John R.
Publicado 2018

“Reasonable adjustments” under the UK's Equality Act 2010: An enquiry into the care and treatment to patients with intellectual disabilities in acute hospital settings

por Redley, Marcus, Lancaster, Isabella, Pitt, Adam, Holland, Anthony, Thompson, Angela, Bradley, John R., Glover, Gyles, Thomson, Karen, Jones, Sara, Herbert, Bernadette, Holme, Anita, Clare, Isabel C. H.
Publicado 2019

Tumor necrosis factor receptor 2-signaling in CD133-expressing cells in renal clear cell carcinoma

por Al-Lamki, Rafia S, Wang, Jun, Yang, Jun, Burrows, Natalie, Maxwell, Patrick H, Eisen, Timothy, Warren, Anne Y, Vanharanta, Sakari, Pacey, Simon, Vandenabeele, Peter, Pober, Jordan S, Bradley, John R
Publicado 2016

Effect of kidney donation on bone mineral metabolism

por Hiemstra, Thomas F., Smith, Jane C., Lim, Kenneth, Xu, Dihua, Kulkarni, Shreya, Bradley, J. Andrew, Paapstel, Kaido, Schoenmakers, Inez, Bradley, John R., Tomlinson, Laurie, McEniery, Carmel M., Wilkinson, Ian B.
Publicado 2020

Evidence of previous SARS-CoV-2 infection in seronegative patients with long COVID

por Krishna, Benjamin A., Lim, Eleanor Y., Mactavous, Lenette, Lyons, Paul A., Doffinger, Rainer, Bradley, John R., Smith, Kenneth G.C., Sinclair, John, Matheson, Nicholas J., Lehner, Paul J., Wills, Mark R., Sithole, Nyaradzai
Publicado 2022

The Efficacy of Sunitinib Treatment of Renal Cancer Cells Is Associated with the Protein PHAX In Vitro

por Al-Lamki, Rafia S., Hudson, Nicholas J., Bradley, John R., Warren, Anne Y., Eisen, Tim, Welsh, Sarah J., Riddick, Antony C. P., O’Mahony, Fiach C., Turnbull, Arran, Powles, Thomas, Reverter, Antonio, Harrison, David J., Stewart, Grant D.
Publicado 2020

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling

por Hurst, Liam A., Dunmore, Benjamin J., Long, Lu, Crosby, Alexi, Al-Lamki, Rafia, Deighton, John, Southwood, Mark, Yang, Xudong, Nikolic, Marko Z., Herrera, Blanca, Inman, Gareth J., Bradley, John R., Rana, Amer A., Upton, Paul D., Morrell, Nicholas W.
Publicado 2017

Hospitalisation for COVID-19 predicts long lasting cerebrovascular impairment: A prospective observational cohort study

por Tsvetanov, Kamen A., Spindler, Lennart R.B., Stamatakis, Emmanuel A., Newcombe, Virginia F.J., Lupson, Victoria C., Chatfield, Doris A., Manktelow, Anne E., Outtrim, Joanne G., Elmer, Anne, Kingston, Nathalie, Bradley, John R., Bullmore, Edward T., Rowe, James B., Menon, David K.
Publicado 2022

Proteomic analysis of circulating immune cells identifies cellular phenotypes associated with COVID-19 severity

por Potts, Martin, Fletcher-Etherington, Alice, Nightingale, Katie, Mescia, Federica, Bergamaschi, Laura, Calero-Nieto, Fernando J., Antrobus, Robin, Williamson, James, Parsons, Harriet, Huttlin, Edward L., Kingston, Nathalie, Göttgens, Berthold, Bradley, John R., Lehner, Paul J., Matheson, Nicholas J., Smith, Kenneth G.C., Wills, Mark R., Lyons, Paul A., Weekes, Michael P.
Publicado 2023

Phenotypic screening reveals TNFR2 as a promising target for cancer immunotherapy

por Williams, Geoffrey S., Mistry, Bina, Guillard, Sandrine, Ulrichsen, Jane Coates, Sandercock, Alan M., Wang, Jun, González-Muñoz, Andrea, Parmentier, Julie, Black, Chelsea, Soden, Jo, Freeth, Jim, Jovanović, Jelena, Leyland, Rebecca, Al-Lamki, Rafia S., Leishman, Andrew J., Rust, Steven J., Stewart, Ross, Jermutus, Lutz, Bradley, John R., Bedian, Vahe, Valge-Archer, Viia, Minter, Ralph, Wilkinson, Robert W.
Publicado 2016

B cell receptor repertoire kinetics after SARS-CoV-2 infection and vaccination

por Kotagiri, Prasanti, Mescia, Federica, Rae, William M., Bergamaschi, Laura, Tuong, Zewen K., Turner, Lorinda, Hunter, Kelvin, Gerber, Pehuén P., Hosmillo, Myra, Hess, Christoph, Clatworthy, Menna R., Goodfellow, Ian G., Matheson, Nicholas J., McKinney, Eoin F., Wills, Mark R., Gupta, Ravindra K., Bradley, John R., Bashford-Rogers, Rachael J.M., Lyons, Paul A., Smith, Kenneth G.C.
Publicado 2022

The impact of hypoxia on B cells in COVID-19

por Kotagiri, Prasanti, Mescia, Federica, Hanson, Aimee L., Turner, Lorinda, Bergamaschi, Laura, Peñalver, Ana, Richoz, Nathan, Moore, Stephen D., Ortmann, Brian M., Dunmore, Benjamin J., Morgan, Michael D., Tuong, Zewen Kelvin, Göttgens, Berthold, Toshner, Mark, Hess, Christoph, Maxwell, Patrick. H., Clatworthy, Menna. R., Nathan, James A., Bradley, John R., Lyons, Paul A., Burrows, Natalie, Smith, Kenneth G.C.
Publicado 2022

A patient-centric modeling framework captures recovery from SARS-CoV-2 infection

por Ruffieux, Hélène, Hanson, Aimee L., Lodge, Samantha, Lawler, Nathan G., Whiley, Luke, Gray, Nicola, Nolan, Tui H., Bergamaschi, Laura, Mescia, Federica, Turner, Lorinda, de Sa, Aloka, Pelly, Victoria S., Kotagiri, Prasanti, Kingston, Nathalie, Bradley, John R., Holmes, Elaine, Wist, Julien, Nicholson, Jeremy K., Lyons, Paul A., Smith, Kenneth G. C., Richardson, Sylvia, Bantug, Glenn R., Hess, Christoph
Publicado 2023

Evaluation of interventions to prevent vasovagal reactions among whole blood donors: rationale and design of a large cluster randomised trial

por McMahon, Amy, Kaptoge, Stephen, Walker, Matthew, Mehenny, Susan, Gilchrist, Philippe T, Sambrook, Jennifer, Akhtar, Naim, Sweeting, Michael, Wood, Angela M, Stirrups, Kathleen, Chung, Ryan, Fahle, Sarah, Johnson, Elisha, Cullen, Donna, Godfrey, Rosemary, Duthie, Shannon, Allen, Louise, Harvey, Paul, Berkson, Michael, Allen, Elizabeth, Watkins, Nicholas A, Bradley, John R, Kingston, Nathalie, Miflin, Gail, Armitage, Jane, Roberts, David J, Danesh, John, Di Angelantonio, Emanuele
Publicado 2023

Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission

por Rivett, Lucy, Sridhar, Sushmita, Sparkes, Dominic, Routledge, Matthew, Jones, Nick K, Forrest, Sally, Young, Jamie, Pereira-Dias, Joana, Hamilton, William L, Ferris, Mark, Torok, M Estee, Meredith, Luke, Curran, Martin D, Fuller, Stewart, Chaudhry, Afzal, Shaw, Ashley, Samworth, Richard J, Bradley, John R, Dougan, Gordon, Smith, Kenneth GC, Lehner, Paul J, Matheson, Nicholas J, Wright, Giles, Goodfellow, Ian G, Baker, Stephen, Weekes, Michael P
Publicado 2020