Opposing effects of KDM6A and JDP2 on glucocorticoid sensitivity in T-ALL

por Levinson, Anya L., Tjoa, Karensa, Huang, Benjamin, Meyer, Lauren K., Kim, Mi-Ok, Brady, Samuel W., Zhang, Jinghui, Shannon, Kevin, Wandler, Anica M.
Publicado 2023

A `one-two punch' therapy strategy to target chemoresistance in estrogen receptor positive breast cancer

por Chi, Feng, Liu, Jiayi, Brady, Samuel W., Cosgrove, Patrick A., Nath, Aritro, McQuerry, Jasmine A., Majumdar, Sumana, Moos, Philip J., Chang, Jeffrey T., Kahn, Michael, Bild, Andrea H.
Publicado 2020

The landscape of coding RNA editing events in pediatric cancer

por Wen, Ji, Rusch, Michael, Brady, Samuel W., Shao, Ying, Edmonson, Michael N., Shaw, Timothy I., Powers, Brent B., Tian, Liqing, Easton, John, Mullighan, Charles G., Gruber, Tanja, Ellison, David, Zhang, Jinghui
Publicado 2021

Novel temporal and spatial patterns of metastatic colonization from breast cancer rapid-autopsy tumor biopsies

por Huang, Xiaomeng, Qiao, Yi, Brady, Samuel W., Factor, Rachel E., Downs-Kelly, Erinn, Farrell, Andrew, McQuerry, Jasmine A., Shrestha, Gajendra, Jenkins, David, Johnson, W. Evan, Cohen, Adam L., Bild, Andrea H., Marth, Gabor T.
Publicado 2021

Convergent evolution and multi-wave clonal invasion in H3 K27-altered diffuse midline gliomas treated with a PDGFR inhibitor

por Arunachalam, Sasi, Szlachta, Karol, Brady, Samuel W., Ma, Xiaotu, Ju, Bensheng, Shaner, Bridget, Mulder, Heather L., Easton, John, Raphael, Benjamin J., Myers, Matthew, Tinkle, Christopher, Allen, Sariah J., Orr, Brent A., Wetmore, Cynthia J., Baker, Suzanne J., Zhang, Jinghui
Publicado 2022

Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations

por Brady, Samuel W., Liu, Yanling, Ma, Xiaotu, Gout, Alexander M., Hagiwara, Kohei, Zhou, Xin, Wang, Jian, Macias, Michael, Chen, Xiaolong, Easton, John, Mulder, Heather L., Rusch, Michael, Wang, Lu, Nakitandwe, Joy, Lei, Shaohua, Davis, Eric M., Naranjo, Arlene, Cheng, Cheng, Maris, John M., Downing, James R., Cheung, Nai-Kong V., Hogarty, Michael D., Dyer, Michael A., Zhang, Jinghui
Publicado 2020

The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms

por Schwartz, Jason R., Ma, Jing, Kamens, Jennifer, Westover, Tamara, Walsh, Michael P., Brady, Samuel W., Robert Michael, J., Chen, Xiaolong, Montefiori, Lindsey, Song, Guangchun, Wu, Gang, Wu, Huiyun, Branstetter, Cristyn, Hiltenbrand, Ryan, Walsh, Michael F., Nichols, Kim E., Maciaszek, Jamie L., Liu, Yanling, Kumar, Priyadarshini, Easton, John, Newman, Scott, Rubnitz, Jeffrey E., Mullighan, Charles G., Pounds, Stanley, Zhang, Jinghui, Gruber, Tanja, Ma, Xiaotu, Klco, Jeffery M.
Publicado 2021

The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma

por Pan, Min, Wright, William C., Chapple, Richard H., Zubair, Asif, Sandhu, Manbir, Batchelder, Jake E., Huddle, Brandt C., Low, Jonathan, Blankenship, Kaley B., Wang, Yingzhe, Gordon, Brittney, Archer, Payton, Brady, Samuel W., Natarajan, Sivaraman, Posgai, Matthew J., Schuetz, John, Miller, Darcie, Kalathur, Ravi, Chen, Siquan, Connelly, Jon Patrick, Babu, M. Madan, Dyer, Michael A., Pruett-Miller, Shondra M., Freeman, Burgess B., Chen, Taosheng, Godley, Lucy A., Blanchard, Scott C., Stewart, Elizabeth, Easton, John, Geeleher, Paul
Publicado 2021

Combating subclonal evolution of resistant cancer phenotypes

por Brady, Samuel W., McQuerry, Jasmine A., Qiao, Yi, Piccolo, Stephen R., Shrestha, Gajendra, Jenkins, David F., Layer, Ryan M., Pedersen, Brent S., Miller, Ryan H., Esch, Amanda, Selitsky, Sara R., Parker, Joel S., Anderson, Layla A., Dalley, Brian K., Factor, Rachel E., Reddy, Chakravarthy B., Boltax, Jonathan P., Li, Dean Y., Moos, Philip J., Gray, Joe W., Heiser, Laura M., Buys, Saundra S., Cohen, Adam L., Johnson, W. Evan, Quinlan, Aaron R., Marth, Gabor, Werner, Theresa L., Bild, Andrea H.
Publicado 2017

Publisher Correction: Combating subclonal evolution of resistant cancer phenotypes

por Brady, Samuel W., McQuerry, Jasmine A., Qiao, Yi, Piccolo, Stephen R., Shrestha, Gajendra, Jenkins, David F., Layer, Ryan M., Pedersen, Brent S., Miller, Ryan H., Esch, Amanda, Selitsky, Sara R., Parker, Joel S., Anderson, Layla A., Dalley, Brian K., Factor, Rachel E., Reddy, Chakravarthy B., Boltax, Jonathan P., Li, Dean Y., Moos, Philip J., Gray, Joe W., Heiser, Laura M., Buys, Saundra S., Cohen, Adam L., Johnson, W. Evan, Quinlan, Aaron R., Marth, Gabor, Werner, Theresa L., Bild, Andrea H.
Publicado 2018

Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor

por Islam, S.M. Ashiqul, Díaz-Gay, Marcos, Wu, Yang, Barnes, Mark, Vangara, Raviteja, Bergstrom, Erik N., He, Yudou, Vella, Mike, Wang, Jingwei, Teague, Jon W., Clapham, Peter, Moody, Sarah, Senkin, Sergey, Li, Yun Rose, Riva, Laura, Zhang, Tongwu, Gruber, Andreas J., Steele, Christopher D., Otlu, Burçak, Khandekar, Azhar, Abbasi, Ammal, Humphreys, Laura, Syulyukina, Natalia, Brady, Samuel W., Alexandrov, Boian S., Pillay, Nischalan, Zhang, Jinghui, Adams, David J., Martincorena, Iñigo, Wedge, David C., Landi, Maria Teresa, Brennan, Paul, Stratton, Michael R., Rozen, Steven G., Alexandrov, Ludmil B.
Publicado 2022

Genomes for Kids: The Scope of Pathogenic Mutations in Pediatric Cancer Revealed by Comprehensive DNA and RNA Sequencing

por Newman, Scott, Nakitandwe, Joy, Kesserwan, Chimene A., Azzato, Elizabeth M., Wheeler, David A., Rusch, Michael, Shurtleff, Sheila, Hedges, Dale J., Hamilton, Kayla V., Foy, Scott G., Edmonson, Michael N., Thrasher, Andrew, Bahrami, Armita, Orr, Brent A., Klco, Jeffery M., Gu, Jiali, Harrison, Lynn W., Wang, Lu, Clay, Michael R., Ouma, Annastasia, Silkov, Antonina, Liu, Yanling, Zhang, Zhaojie, Liu, Yu, Brady, Samuel W., Zhou, Xin, Chang, Ti-Cheng, Pande, Manjusha, Davis, Eric, Becksfort, Jared, Patel, Aman, Wilkinson, Mark R., Rahbarinia, Delaram, Kubal, Manish, Maciaszek, Jamie L., Pastor, Victor, Knight, Jay, Gout, Alexander M., Wang, Jian, Gu, Zhaohui, Mullighan, Charles G., McGee, Rose B., Quinn, Emily A., Nuccio, Regina, Mostafavi, Roya, Gerhardt, Elsie L., Taylor, Leslie M., Valdez, Jessica M., Hines-Dowell, Stacy J., Pappo, Alberto S., Robinson, Giles, Johnson, Liza-Marie, Pui, Ching-Hon, Ellison, David W., Downing, James R., Zhang, Jinghui, Nichols, Kim E.
Publicado 2021