Artificial Intelligence-Based Computational Screening and Functional Assays Identify Candidate Small Molecule Antagonists of PTPmu-Dependent Adhesion

por Molyneaux, Kathleen, Laggner, Christian, Brady-Kalnay, Susann M.
Publicado 2023

A novel binding pocket in the D2 domain of protein tyrosine phosphatase mu (PTPmu) guides AI screen to identify small molecules that modulate tumour cell adhesion, growth and migra...

por Molyneaux, Kathleen, Laggner, Christian, Brady‐Kalnay, Susann M.
Publicado 2023

PTPμ Regulates N-Cadherin–dependent Neurite Outgrowth

por Burden-Gulley, Susan M., Brady-Kalnay, Susann M.
Publicado 1999

Small molecule antagonists of PTPmu identified by artificial intelligence-based computational screening block glioma cell migration and growth

por Molyneaux, Kathleen, Laggner, Christian, Vincent, Jason, Brady-Kalnay, Susann
Publicado 2023

Sustained Delivery of Activated Rho GTPases and BDNF Promotes Axon Growth in CSPG-Rich Regions Following Spinal Cord Injury

por Jain, Anjana, McKeon, Robert J., Brady-Kalnay, Susann M., Bellamkonda, Ravi V.
Publicado 2011

α3β1 integrin–CD151, a component of the cadherin–catenin complex, regulates PTPμ expression and cell–cell adhesion

por Chattopadhyay, Nibedita, Wang, Zemin, Ashman, Leonie K., Brady-Kalnay, Susann M., Kreidberg, Jordan A.
Publicado 2003

Generation of Glioblastoma Patient-Derived Intracranial Xenografts for Preclinical Studies

por Kerstetter-Fogle, Amber E., Harris, Peggy L. R., Brady-Kalnay, Susann M., Sloan, Andrew E.
Publicado 2020

Ultrasound-Based Molecular Imaging of Tumors with PTPmu Biomarker-Targeted Nanobubble Contrast Agents

por Johansen, Mette L., Perera, Reshani, Abenojar, Eric, Wang, Xinning, Vincent, Jason, Exner, Agata A., Brady-Kalnay, Susann M.
Publicado 2021

Mapping the Mechanome of Live Stem Cells Using a Novel Method to Measure Local Strain Fields In Situ at the Fluid-Cell Interface

por Song, Min Jae, Brady-Kalnay, Susann M., McBride, Sara H., Phillips-Mason, Polly, Dean, David, Knothe Tate, Melissa L.
Publicado 2012

Detection of Tumor-Specific PTPmu in Gynecological Cancer and Patient Derived Xenografts

por Vincent, Jason, Craig, Sonya E. L., Johansen, Mette L., Narla, Jyosthna, Avril, Stefanie, DiFeo, Analisa, Brady-Kalnay, Susann M.
Publicado 2021

Dynamic Quantitative T1 Mapping in Orthotopic Brain Tumor Xenografts()

por Herrmann, Kelsey, Erokwu, Bernadette O., Johansen, Mette L., Basilion, James P., Gulani, Vikas, Griswold, Mark A., Flask, Chris A., Brady-Kalnay, Susann M.
Publicado 2016

A PTPmu Biomarker is Associated with Increased Survival in Gliomas

por Johansen, Mette L., Vincent, Jason, Gittleman, Haley, Craig, Sonya E. L., Couce, Marta, Sloan, Andrew E., Barnholtz-Sloan, Jill S., Brady-Kalnay, Susann M.
Publicado 2019

Dynamic Interaction of PTPμ with Multiple Cadherins In Vivo

por Brady-Kalnay, Susann M., Mourton, Tracy, Nixon, Joseph P., Pietz, Gregory E., Kinch, Michael, Chen, Haiyan, Brackenbury, Robert, Rimm, David L., Del Vecchio, Robert L., Tonks, Nicholas K.
Publicado 1998

Dual Contrast - Magnetic Resonance Fingerprinting (DC-MRF): A Platform for Simultaneous Quantification of Multiple MRI Contrast Agents

por Anderson, Christian E., Donnola, Shannon B., Jiang, Yun, Batesole, Joshua, Darrah, Rebecca, Drumm, Mitchell L., Brady-Kalnay, Susann M., Steinmetz, Nicole F., Yu, Xin, Griswold, Mark A., Flask, Chris A.
Publicado 2017

Molecular Imaging of Tumors Using a Quantitative T(1) Mapping Technique via Magnetic Resonance Imaging

por Herrmann, Kelsey, Johansen, Mette L., Craig, Sonya E., Vincent, Jason, Howell, Michael, Gao, Ying, Lu, Lan, Erokwu, Bernadette, Agnes, Richard S., Lu, Zheng-Rong, Pokorski, Jonathan K., Basilion, James, Gulani, Vikas, Griswold, Mark, Flask, Chris, Brady-Kalnay, Susann M.
Publicado 2015

Small Molecule-Based Prodrug Targeting Prostate Specific Membrane Antigen for the Treatment of Prostate Cancer

por Wang, Xinning, Shirke, Aditi, Walker, Ethan, Sun, Rongcan, Ramamurthy, Gopolakrishnan, Wang, Jing, Shan, Lingpeng, Mangadlao, Joey, Dong, Zhipeng, Li, Jing, Wang, Ziying, Schluchter, Mark, Luo, Dong, Wang, Yu, Stauffer, Shaun, Brady-Kalnay, Susann, Hoimes, Christopher, Lee, Zhenghong, Basilion, James P.
Publicado 2021

Dynamic, Simultaneous Concentration Mapping of Multiple MRI Contrast Agents with Dual Contrast - Magnetic Resonance Fingerprinting

por Anderson, Christian E., Johansen, Mette, Erokwu, Bernadette O., Hu, He, Gu, Yuning, Zhang, Yifan, Kavran, Michael, Vincent, Jason, Drumm, Mitchell L., Griswold, Mark A., Steinmetz, Nicole F., Li, Ming, Clark, Heather, Darrah, Rebecca J., Yu, Xin, Brady-Kalnay, Susann M., Flask, Chris A.
Publicado 2019