The Emergence of Model Systems to Investigate the Link Between Traumatic Brain Injury and Alzheimer’s Disease

por Srinivasan, Gayathri, Brafman, David A.
Publicado 2022

The Multifaceted Role of WNT Signaling in Alzheimer’s Disease Onset and Age-Related Progression

por Kostes, William W., Brafman, David A.
Publicado 2023

Biomaterial Approaches for Stem Cell-Based Myocardial Tissue Engineering

por Cutts, Josh, Nikkhah, Mehdi, Brafman, David A
Publicado 2015

May I Cut in? Gene Editing Approaches in Human Induced Pluripotent Stem Cells

por Brookhouser, Nicholas, Raman, Sreedevi, Potts, Christopher, Brafman, David. A.
Publicado 2017

Weighing up the evidence used by direct-to-consumer stem cell businesses

por Cook, Margaret, Richey, Alexandra, Brafman, David A., Frow, Emma K.
Publicado 2021

Endogenous WNT Signaling Regulates hPSC-Derived Neural Progenitor Cell Heterogeneity and Specifies Their Regional Identity

por Moya, Noel, Cutts, Josh, Gaasterland, Terry, Willert, Karl, Brafman, David A.
Publicado 2014

Prime Editing Guide RNA Design Automation Using PINE-CONE

por Standage-Beier, Kylie, Tekel, Stefan J., Brafman, David A., Wang, Xiao
Publicado 2021

APOE2 mitigates disease-related phenotypes in an isogenic hiPSC-based model of Alzheimer’s disease

por Brookhouser, Nicholas, Raman, Sreedevi, Frisch, Carlye, Srinivasan, Gayathri, Brafman, David A.
Publicado 2021

Generation and characterization of two human induced pluripotent stem cell (hiPSC) lines homozygous for the Apolipoprotein e4 (APOE4) risk variant—Alzheimer's disease (ASUi005-A) a...

por Brookhouser, Nicholas, Zhang, Ping, Caselli, Richard, Kim, Jean J., Brafman, David A.
Publicado 2018

A Cas9-mediated adenosine transient reporter enables enrichment of ABE-targeted cells

por Brookhouser, Nicholas, Nguyen, Toan, Tekel, Stefan J., Standage-Beier, Kylie, Wang, Xiao, Brafman, David A.
Publicado 2020

A microcarrier-based protocol for scalable generation and purification of human induced pluripotent stem cell-derived neurons and astrocytes

por Knittel, Jacob, Srinivasan, Gayathri, Frisch, Carlye, Brookhouser, Nicholas, Raman, Sreedevi, Essuman, Albert, Brafman, David A.
Publicado 2022

A transient reporter for editing enrichment (TREE) in human cells

por Standage-Beier, Kylie, Tekel, Stefan J, Brookhouser, Nicholas, Schwarz, Grace, Nguyen, Toan, Wang, Xiao, Brafman, David A
Publicado 2019

BIG-TREE: Base-Edited Isogenic hPSC Line Generation Using a Transient Reporter for Editing Enrichment

por Brookhouser, Nicholas, Tekel, Stefan J., Standage-Beier, Kylie, Nguyen, Toan, Schwarz, Grace, Wang, Xiao, Brafman, David A.
Publicado 2020

A transient reporter for editing enrichment (TREE) in human cells

por Standage-Beier, Kylie, Tekel, Stefan J, Brookhouser, Nicholas, Schwarz, Grace, Nguyen, Toan, Wang, Xiao, Brafman, David A
Publicado 2020

A Defined and Scalable Peptide-Based Platform for the Generation of Human Pluripotent Stem Cell-Derived Astrocytes

por Raman, Sreedevi, Srinivasan, Gayathri, Brookhouser, Nicholas, Nguyen, Toan, Henson, Tanner, Morgan, Daylin, Cutts, Joshua, Brafman, David A.
Publicado 2020

Characterizing Direct-to-Consumer Stem Cell Businesses in the Southwest United States

por Frow, Emma K., Brafman, David A., Muldoon, Anna, Krum, Logan, Williams, Paige, Becker, Bryson, Nelson, John P., Pritchett, Ashley
Publicado 2019

Analysis of SOX2-Expressing Cell Populations Derived from Human Pluripotent Stem Cells

por Brafman, David A., Moya, Noel, Allen-Soltero, Stephanie, Fellner, Thomas, Robinson, Megan, McMillen, Zoë L., Gaasterland, Terry, Willert, Karl
Publicado 2013

PINE-TREE enables highly efficient genetic modification of human cell lines

por Frisch, Carlye, Kostes, William W., Galyon, Brooke, Whitman, Brycelyn, Tekel, Stefan J., Standage-Beier, Kylie, Srinivasan, Gayathri, Wang, Xiao, Brafman, David A.
Publicado 2023

Human Autopsy-Derived Scalp Fibroblast Biobanking for Age-Related Neurodegenerative Disease Research

por Beh, Suet Theng, Frisch, Carlye, Brafman, David A., Churko, Jared, Walker, Jessica E., Serrano, Geidy E., Sue, Lucia I., Reiman, Eric M., Beach, Thomas G., Lue, Lih-Fen
Publicado 2020

APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids

por Zhao, Jing, Fu, Yuan, Yamazaki, Yu, Ren, Yingxue, Davis, Mary D., Liu, Chia-Chen, Lu, Wenyan, Wang, Xue, Chen, Kai, Cherukuri, Yesesri, Jia, Lin, Martens, Yuka A., Job, Lucy, Shue, Francis, Nguyen, Thanh Thanh, Younkin, Steven G., Graff-Radford, Neill R., Wszolek, Zbigniew K., Brafman, David A., Asmann, Yan W., Ertekin-Taner, Nilüfer, Kanekiyo, Takahisa, Bu, Guojun
Publicado 2020