Early IFNγ-Mediated and Late Perforin-Mediated Suppression of Pathogenic CD4 T Cell Responses Are Both Required for Inhibition of Demyelinating Disease by CNS-Specific Autoregulato...

por Boyden, Alexander W., Brate, Ashley A., Karandikar, Nitin J.
Publicado 2018

Novel B cell-dependent multiple sclerosis model using extracellular domains of myelin proteolipid protein

por Boyden, Alexander W., Brate, Ashley A., Karandikar, Nitin J.
Publicado 2020

Therapeutic intervention in relapsing autoimmune demyelinating disease through induction of myelin-specific regulatory CD8 T cell responses

por Brate, Ashley A., Boyden, Alexander W., Itani, Farah R., Pewe, Lecia L., Harty, John T., Karandikar, Nitin J.
Publicado 2019

IL-12-Induced Immune Suppressive Deficit During CD8+ T-Cell Differentiation

por Renavikar, Pranav S., Sinha, Sushmita, Brate, Ashley A., Borcherding, Nicholas, Crawford, Michael P., Steward-Tharp, Scott M., Karandikar, Nitin J.
Publicado 2020

Suppression of autoimmune demyelinating disease by preferential stimulation of CNS-specific CD8 T cells using Listeria-encoded neuroantigen

por Itani, Farah R., Sinha, Sushmita, Brate, Ashley A., Pewe, Lecia L., Gibson-Corley, Katherine N., Harty, John T., Karandikar, Nitin J.
Publicado 2017

Altered expression of SIRPγ on the T-cells of relapsing remitting multiple sclerosis and type 1 diabetes patients could potentiate effector responses from T-cells

por Sinha, Sushmita, Renavikar, Pranav S., Crawford, Michael P., Steward-Tharp, Scott M., Brate, Ashley, Tsalikian, Eva, Tansey, Michael, Shivapour, Ezzatollah T., Cho, Tracey, Kamholz, John, Karandikar, Nitin J.
Publicado 2020