Is it time to rethink the Alzheimer's disease drug development strategy by targeting its silent phase?

por Souchet, Benoit, Audrain, Mickael, Billoir, Baptiste, Lecanu, Laurent, Tada, Satoru, Braudeau, Jérôme
Publicado 2018

Real-Time Monitoring of Exosome Enveloped-AAV Spreading by Endomicroscopy Approach: A New Tool for Gene Delivery in the Brain

por Orefice, Nicola Salvatore, Souchet, Benoît, Braudeau, Jérôme, Alves, Sandro, Piguet, Françoise, Collaud, Fanny, Ronzitti, Giuseppe, Tada, Satoru, Hantraye, Philippe, Mingozzi, Federico, Ducongé, Frédéric, Cartier, Nathalie
Publicado 2019

Alzheimer’s disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression

por Audrain, Mickael, Fol, Romain, Dutar, Patrick, Potier, Brigitte, Billard, Jean-Marie, Flament, Julien, Alves, Sandro, Burlot, Marie-Anne, Dufayet-Chaffaud, Gaelle, Bemelmans, Alexis-Pierre, Valette, Julien, Hantraye, Philippe, Déglon, Nicole, Cartier, Nathalie, Braudeau, Jérome
Publicado 2016

Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice

por Souchet, Benoît, Audrain, Mickael, Billard, Jean Marie, Dairou, Julien, Fol, Romain, Orefice, Nicola Salvatore, Tada, Satoru, Gu, Yuchen, Dufayet-Chaffaud, Gaelle, Limanton, Emmanuelle, Carreaux, François, Bazureau, Jean-Pierre, Alves, Sandro, Meijer, Laurent, Janel, Nathalie, Braudeau, Jérôme, Cartier, Nathalie
Publicado 2019