Targeting Stage-Specific Embryonic Antigen 4 (SSEA-4) in Triple Negative Breast Cancer by CAR T Cells Results in Unexpected on Target/off Tumor Toxicities in Mice

por Pfeifer, Rita, Al Rawashdeh, Wa’el, Brauner, Janina, Martinez-Osuna, Manuel, Lock, Dominik, Herbel, Christoph, Eckardt, Dominik, Assenmacher, Mario, Bosio, Andreas, Hardt, Olaf T., Johnston, Ian C. D.
Publicado 2023

A Novel Siglec-4 Derived Spacer Improves the Functionality of CAR T Cells Against Membrane-Proximal Epitopes

por Schäfer, Daniel, Henze, Janina, Pfeifer, Rita, Schleicher, Anna, Brauner, Janina, Mockel-Tenbrinck, Nadine, Barth, Carola, Gudert, Daniela, Al Rawashdeh, Wa'el, Johnston, Ian C. D., Hardt, Olaf
Publicado 2020

Identification of CD318, TSPAN8 and CD66c as target candidates for CAR T cell based immunotherapy of pancreatic adenocarcinoma

por Schäfer, Daniel, Tomiuk, Stefan, Küster, Laura N., Rawashdeh, Wa’el Al, Henze, Janina, Tischler-Höhle, German, Agorku, David J., Brauner, Janina, Linnartz, Cathrin, Lock, Dominik, Kaiser, Andrew, Herbel, Christoph, Eckardt, Dominik, Lamorte, Melina, Lenhard, Dorothee, Schüler, Julia, Ströbel, Philipp, Missbach-Guentner, Jeannine, Pinkert-Leetsch, Diana, Alves, Frauke, Bosio, Andreas, Hardt, Olaf
Publicado 2021