Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication

por Bravo, Jack P.K., Dangerfield, Tyler L., Taylor, David W., Johnson, Kenneth A.
Publicado 2021

A single 2′-O-methylation of ribosomal RNA gates assembly of a functional ribosome

por Yelland, James N., Bravo, Jack P. K., Black, Joshua J., Taylor, David W., Johnson, Arlen W.
Publicado 2022

Structural basis for broad anti-phage immunity by DISARM

por Bravo, Jack P. K., Aparicio-Maldonado, Cristian, Nobrega, Franklin L., Brouns, Stan J. J., Taylor, David W.
Publicado 2022

RNA targeting unleashes indiscriminate nuclease activity of CRISPR–Cas12a2

por Bravo, Jack P. K., Hallmark, Thomson, Naegle, Bronson, Beisel, Chase L., Jackson, Ryan N., Taylor, David W.
Publicado 2023

Structural basis for assembly of non-canonical small subunits into type I-C Cascade

por O’Brien, Roisin E., Santos, Inês C., Wrapp, Daniel, Bravo, Jack P. K., Schwartz, Evan A., Brodbelt, Jennifer S., Taylor, David W.
Publicado 2020

Stability of local secondary structure determines selectivity of viral RNA chaperones

por Bravo, Jack P K, Borodavka, Alexander, Barth, Anders, Calabrese, Antonio N, Mojzes, Peter, Cockburn, Joseph J B, Lamb, Don C, Tuma, Roman
Publicado 2018

Structure of a type IV CRISPR-Cas ribonucleoprotein complex

por Zhou, Yi, Bravo, Jack P.K., Taylor, Hannah N., Steens, Jurre A., Jackson, Ryan N., Staals, Raymond H.J., Taylor, David W.
Publicado 2021

Structural rearrangements allow nucleic acid discrimination by type I-D Cascade

por Schwartz, Evan A., McBride, Tess M., Bravo, Jack P. K., Wrapp, Daniel, Fineran, Peter C., Fagerlund, Robert D., Taylor, David W.
Publicado 2022

Structural basis for mismatch surveillance by CRISPR–Cas9

por Bravo, Jack P. K., Liu, Mu-Sen, Hibshman, Grace N., Dangerfield, Tyler L., Jung, Kyungseok, McCool, Ryan S., Johnson, Kenneth A., Taylor, David W.
Publicado 2022

Publisher Correction: Structural basis for mismatch surveillance by CRISPR–Cas9

por Bravo, Jack P. K., Liu, Mu-Sen, Hibshman, Grace N., Dangerfield, Tyler L., Jung, Kyungseok, McCool, Ryan S., Johnson, Kenneth A., Taylor, David W.
Publicado 2022

Structural basis of rotavirus RNA chaperone displacement and RNA annealing

por Bravo, Jack P. K., Bartnik, Kira, Venditti, Luca, Acker, Julia, Gail, Emma H., Colyer, Alice, Davidovich, Chen, Lamb, Don C., Tuma, Roman, Calabrese, Antonio N., Borodavka, Alexander
Publicado 2021

Type III CRISPR-Cas complexes act as protein-assisted ribozymes during target RNA cleavage

por Schwartz, Evan A., Bravo, Jack P.K., Ahsan, Mohd, Macias, Luis A., McCafferty, Caitlyn L., Dangerfield, Tyler L., Walker, Jada N., Brodbelt, Jennifer S., Palermo, Giulia, Fineran, Peter C., Fagerlund, Robert D., Taylor, David W.
Publicado 2023

SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation

por Steens, Jurre A., Zhu, Yifan, Taylor, David W., Bravo, Jack P. K., Prinsen, Stijn H. P., Schoen, Cor D., Keijser, Bart J. F., Ossendrijver, Michel, Hofstra, L. Marije, Brouns, Stan J. J., Shinkai, Akeo, van der Oost, John, Staals, Raymond H. J.
Publicado 2021