CellProfiler Tracer: exploring and validating high-throughput, time-lapse microscopy image data

por Bray, Mark-Anthony, Carpenter, Anne E.
Publicado 2015

Activity of the novel polo-like kinase 4 inhibitor CFI-400945 in pancreatic cancer patient-derived xenografts

por Lohse, Ines, Mason, Jacqueline, Mary, Pinjiang Cao, Pintilie, Melania, Bray, Mark, Hedley, David W
Publicado 2016

Automated image-based assay for evaluation of HIV neutralization and cell-to-cell fusion inhibition

por Sheik-Khalil, Enas, Bray, Mark-Anthony, Özkaya Şahin, Gülsen, Scarlatti, Gabriella, Jansson, Marianne, Carpenter, Anne E, Fenyö, Eva Maria
Publicado 2014

Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects

por Singh, Shantanu, Wu, Xiaoyun, Ljosa, Vebjorn, Bray, Mark-Anthony, Piccioni, Federica, Root, David E., Doench, John G., Boehm, Jesse S., Carpenter, Anne E.
Publicado 2015

Systematic morphological profiling of human gene and allele function via Cell Painting

por Rohban, Mohammad Hossein, Singh, Shantanu, Wu, Xiaoyun, Berthet, Julia B, Bray, Mark-Anthony, Shrestha, Yashaswi, Varelas, Xaralabos, Boehm, Jesse S, Carpenter, Anne E
Publicado 2017

Self-Organization of Muscle Cell Structure and Function

por Grosberg, Anna, Kuo, Po-Ling, Guo, Chin-Lin, Geisse, Nicholas A., Bray, Mark-Anthony, Adams, William J., Sheehy, Sean P., Parker, Kevin Kit
Publicado 2011

GATA1 deletion in human pluripotent stem cells increases differentiation yield and maturity of neutrophils

por Harper, Thomas C., Oberlick, Elaine M., Smith, Tomas J., Nunes, Duncan E., Bray, Mark-Anthony, Park, Seonmi, Driscoll, Corey D., Mowbray, Sarah F., Antczak, Christophe
Publicado 2023

The tetrapeptide sequence of IL-1β regulates its recruitment and activation by inflammatory caspases

por Exconde, Patrick M., Hernandez-Chavez, Claudia, Bray, Mark B., Lopez, Jan L., Srivastava, Tamanna, Egan, Marisa S., Zhang, Jenna, Shin, Sunny, Discher, Bohdana M., Taabazuing, Cornelius Y.
Publicado 2023

Inhibition of the spindle assembly checkpoint kinase Mps-1 as a novel therapeutic strategy in malignant mesothelioma

por Szymiczek, Agata, Carbone, Michele, Pastorino, Sandra, Napolitano, Andrea, Tanji, Mika, Minaai, Michael, Pagano, Ian, Mason, Jacqueline M., Pass, Harvey I., Bray, Mark R., Mak, Tak W., Yang, Haining
Publicado 2017

Cell Painting predicts impact of lung cancer variants

por Caicedo, Juan C., Arevalo, John, Piccioni, Federica, Bray, Mark-Anthony, Hartland, Cathy L., Wu, Xiaoyun, Brooks, Angela N., Berger, Alice H., Boehm, Jesse S., Carpenter, Anne E., Singh, Shantanu
Publicado 2022

Identification of Host-Targeted Small Molecules That Restrict Intracellular Mycobacterium tuberculosis Growth

por Stanley, Sarah A., Barczak, Amy K., Silvis, Melanie R., Luo, Samantha S., Sogi, Kimberly, Vokes, Martha, Bray, Mark-Anthony, Carpenter, Anne E., Moore, Christopher B., Siddiqi, Noman, Rubin, Eric J., Hung, Deborah T.
Publicado 2014

A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport

por Shlevkov, Evgeny, Basu, Himanish, Bray, Mark-Anthony, Sun, Zheng, Wei, Wei, Apaydin, Kaan, Karhohs, Kyle, Chen, Pin-Fang, Smith, Janell L.M., Wiskow, Ole, Roet, Kasper, Huang, Xuan, Eggan, Kevin, Carpenter, Anne E., Kleiman, Robin J., Schwarz, Thomas L.
Publicado 2019

Fcmr regulates mononuclear phagocyte control of anti-tumor immunity

por Kubli, Shawn P., Vornholz, Larsen, Duncan, Gordon, Zhou, Wenjing, Ramachandran, Parameswaran, Fortin, Jerome, Cox, Maureen, Han, SeongJun, Nechanitzky, Robert, Nechanitzky, Duygu, Snow, Bryan E., Jones, Lisa, Li, Wanda Y., Haight, Jillian, Wakeham, Andrew, Bray, Mark R., Mak, Tak W.
Publicado 2019

Author Correction: Fcmr regulates mononuclear phagocyte control of anti-tumor immunity

por Kubli, Shawn P., Vornholz, Larsen, Duncan, Gordon, Zhou, Wenjing, Ramachandran, Parameswaran, Fortin, Jerome, Cox, Maureen, Han, SeongJun, Nechanitzky, Robert, Nechanitzky, Duygu, Snow, Bryan E., Jones, Lisa, Li, Wanda Y., Haight, Jillian, Wakeham, Andrew, Bray, Mark R., Mak, Tak W.
Publicado 2019

Safety and tolerability of CFI-400945, a first-in-class, selective PLK4 inhibitor in advanced solid tumours: a phase 1 dose-escalation trial

por Veitch, Zachary W., Cescon, David W., Denny, Trisha, Yonemoto, Lisa-Maria, Fletcher, Graham, Brokx, Richard, Sampson, Peter, Li, Sze-Wan, Pugh, Trevor J., Bruce, Jeffrey, Bray, Mark R., Slamon, Dennis J., Mak, Tak W., Wainberg, Zev A., Bedard, Philippe L.
Publicado 2019

Systematic, multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence

por Barczak, Amy K., Avraham, Roi, Singh, Shantanu, Luo, Samantha S., Zhang, Wei Ran, Bray, Mark-Anthony, Hinman, Amelia E., Thompson, Matthew, Nietupski, Raymond M., Golas, Aaron, Montgomery, Paul, Fitzgerald, Michael, Smith, Roger S., White, Dylan W., Tischler, Anna D., Carpenter, Anne E., Hung, Deborah T.
Publicado 2017

The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor–resistant ER(+) breast cancer with mitotic aberrations

por Soria-Bretones, Isabel, Thu, Kelsie L., Silvester, Jennifer, Cruickshank, Jennifer, El Ghamrasni, Samah, Ba-alawi, Wail, Fletcher, Graham C., Kiarash, Reza, Elliott, Mitchell J., Chalmers, Jordan J., Elia, Andrea C., Cheng, Albert, Rose, April A. N., Bray, Mark R., Haibe-Kains, Benjamin, Mak, Tak W., Cescon, David W.
Publicado 2022

P471: POLO-LIKE KINASE 4 INHIBITION INDUCED ANTI-LEUKAEMIC EFFECTS THROUGH HISTONE MODIFICATION IN TP53 MUTATED ACUTE MYELOID LEUKAEMIA

por Lam, Wing, Dang, Kenny, Him Man, Cheuk, Zeng, Xiao-Yuan, Zheng, Lichuan, Ka-Lam Ng, Nelson, Chan, Koon-Chuen, Kwok, Tsz-Ho, Chi-Chun Ng, Timothy, Leung, Wing-Yan, Shing-Yan Huen, Michael, Chak-Lui Wong, Carmen, Wai Eric So, Chi, Dou, Zhixun, Robert Bray, Mark, Mak, Tak, Yh Leung, Anskar
Publicado 2023

COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England

por Mafham, Marion M, Spata, Enti, Goldacre, Raphael, Gair, Dominic, Curnow, Paula, Bray, Mark, Hollings, Sam, Roebuck, Chris, Gale, Chris P, Mamas, Mamas A, Deanfield, John E, de Belder, Mark A, Luescher, Thomas F, Denwood, Tom, Landray, Martin J, Emberson, Jonathan R, Collins, Rory, Morris, Eva J A, Casadei, Barbara, Baigent, Colin
Publicado 2020

Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma

por Du, Ziming, Abedalthagafi, Malak, Aizer, Ayal A., McHenry, Allison R., Sun, Heather H., Bray, Mark-Anthony, Viramontes, Omar, Machaidze, Revaz, Brastianos, Priscilla K., Reardon, David A., Dunn, Ian F., Freeman, Gordon J., Ligon, Keith L., Carpenter, Anne E., Alexander, Brian M., Agar, Nathalie Y., Rodig, Scott J., Bradshaw, Elizabeth M., Santagata, Sandro
Publicado 2014