Highlight report: Import of fatty acids by metastasizing tumor cells

por Brecklinghaus, Tim
Publicado 2018

Role of autophagy in drug induced liver injury

por Brecklinghaus, Tim
Publicado 2020

Roadmap for the development of alternative test methods

por Brecklinghaus, Tim
Publicado 2020

Guidance for statistical design and analysis of toxicological dose–response experiments, based on a comprehensive literature review

por Kappenberg, Franziska, Duda, Julia C., Schürmeyer, Leonie, Gül, Onur, Brecklinghaus, Tim, Hengstler, Jan G., Schorning, Kirsten, Rahnenführer, Jörg
Publicado 2023

Handling deviating control values in concentration-response curves

por Kappenberg, Franziska, Brecklinghaus, Tim, Albrecht, Wiebke, Blum, Jonathan, van der Wurp, Carola, Leist, Marcel, Hengstler, Jan G., Rahnenführer, Jörg
Publicado 2020

Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes

por Wijaya, Lukas S., Rau, Carina, Braun, Theresa S., Marangoz, Serif, Spegg, Vincent, Vlasveld, Matthijs, Albrecht, Wiebke, Brecklinghaus, Tim, Kamp, Hennicke, Beltman, Joost B., Hengstler, Jan G., van de Water, Bob, Leist, Marcel, Schildknecht, Stefan
Publicado 2021

Histone deacetylase 5 regulates interleukin 6 secretion and insulin action in skeletal muscle

por Klymenko, Oleksiy, Brecklinghaus, Tim, Dille, Matthias, Springer, Christian, de Wendt, Christian, Altenhofen, Delsi, Binsch, Christian, Knebel, Birgit, Scheller, Jürgen, Hardt, Christopher, Herwig, Ralf, Chadt, Alexandra, Pfluger, Paul T., Al-Hasani, Hadi, Kabra, Dhiraj G.
Publicado 2020

Comparing in vitro human liver models to in vivo human liver using RNA-Seq

por Gupta, Rajinder, Schrooders, Yannick, Hauser, Duncan, van Herwijnen, Marcel, Albrecht, Wiebke, ter Braak, Bas, Brecklinghaus, Tim, Castell, Jose V., Elenschneider, Leroy, Escher, Sylvia, Guye, Patrick, Hengstler, Jan G., Ghallab, Ahmed, Hansen, Tanja, Leist, Marcel, Maclennan, Richard, Moritz, Wolfgang, Tolosa, Laia, Tricot, Tine, Verfaillie, Catherine, Walker, Paul, van de Water, Bob, Kleinjans, Jos, Caiment, Florian
Publicado 2020

Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity

por Ghallab, Ahmed, Hassan, Reham, Hofmann, Ute, Friebel, Adrian, Hobloss, Zaynab, Brackhagen, Lisa, Begher-Tibbe, Brigitte, Myllys, Maiju, Reinders, Joerg, Overbeck, Nina, Sezgin, Selahaddin, Zühlke, Sebastian, Seddek, Abdel-latif, Murad, Walaa, Brecklinghaus, Tim, Kappenberg, Franziska, Rahnenführer, Jörg, González, Daniela, Goldring, Christopher, Copple, Ian M., Marchan, Rosemarie, Longerich, Thomas, Vucur, Mihael, Luedde, Tom, Urban, Stephan, Canbay, Ali, Schreiter, Thomas, Trauner, Michael, Akakpo, Jephte Y., Olyaee, Mojtaba, Curry, Steven C., Sowa, Jan-Peter, Jaeschke, Hartmut, Hoehme, Stefan, Hengstler, Jan G.
Publicado 2022

The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods

por Krebs, Alice, van Vugt-Lussenburg, Barbara M. A., Waldmann, Tanja, Albrecht, Wiebke, Boei, Jan, ter Braak, Bas, Brajnik, Maja, Braunbeck, Thomas, Brecklinghaus, Tim, Busquet, Francois, Dinnyes, Andras, Dokler, Joh, Dolde, Xenia, Exner, Thomas E., Fisher, Ciarán, Fluri, David, Forsby, Anna, Hengstler, Jan G., Holzer, Anna-Katharina, Janstova, Zofia, Jennings, Paul, Kisitu, Jaffar, Kobolak, Julianna, Kumar, Manoj, Limonciel, Alice, Lundqvist, Jessica, Mihalik, Balázs, Moritz, Wolfgang, Pallocca, Giorgia, Ulloa, Andrea Paola Cediel, Pastor, Manuel, Rovida, Costanza, Sarkans, Ugis, Schimming, Johannes P., Schmidt, Bela Z., Stöber, Regina, Strassfeld, Tobias, van de Water, Bob, Wilmes, Anja, van der Burg, Bart, Verfaillie, Catherine M., von Hellfeld, Rebecca, Vrieling, Harry, Vrijenhoek, Nanette G., Leist, Marcel
Publicado 2020