Norpa Signalling and the Seasonal Circadian Locomotor Phenotype in Drosophila

por Breda, Carlo, Rosato, Ezio, Kyriacou, Charalambos P.
Publicado 2020

Drosophila Nrf2/Keap1 Mediated Redox Signaling Supports Synaptic Function and Longevity and Impacts on Circadian Activity

por Spiers, Jereme G., Breda, Carlo, Robinson, Sue, Giorgini, Flaviano, Steinert, Joern R.
Publicado 2019

Esculetin Provides Neuroprotection against Mutant Huntingtin-Induced Toxicity in Huntington’s Disease Models

por Pruccoli, Letizia, Breda, Carlo, Teti, Gabriella, Falconi, Mirella, Giorgini, Flaviano, Tarozzi, Andrea
Publicado 2021

Effect of the Citrus Flavone Nobiletin on Circadian Rhythms and Metabolic Syndrome

por Neba Ambe, Gael N. N., Breda, Carlo, Bhambra, Avninder Singh, Arroo, Randolph R. J.
Publicado 2022

Connectivity mapping uncovers small molecules that modulate neurodegeneration in Huntington’s disease models

por Smalley, Joshua L., Breda, Carlo, Mason, Robert P., Kooner, Gurdeep, Luthi-Carter, Ruth, Gant, Timothy W., Giorgini, Flaviano
Publicado 2015

Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviour

por Breda, Carlo, Nugent, Marie L., Estranero, Jasper G., Kyriacou, Charalambos P., Outeiro, Tiago F., Steinert, Joern R., Giorgini, Flaviano
Publicado 2015

Copy-number variation of the neuronal glucose transporter gene SLC2A3 and age of onset in Huntington's disease

por Vittori, Angelica, Breda, Carlo, Repici, Mariaelena, Orth, Michael, Roos, Raymund A.C., Outeiro, Tiago F., Giorgini, Flaviano, Hollox, Edward J.
Publicado 2014

A novel role for kynurenine 3-monooxygenase in mitochondrial dynamics

por Maddison, Daniel C., Alfonso-Núñez, Mónica, Swaih, Aisha M., Breda, Carlo, Campesan, Susanna, Allcock, Natalie, Straatman-Iwanowska, Anna, Kyriacou, Charalambos P., Giorgini, Flaviano
Publicado 2020

Glycation potentiates neurodegeneration in models of Huntington’s disease

por Vicente Miranda, Hugo, Gomes, Marcos António, Branco-Santos, Joana, Breda, Carlo, Lázaro, Diana F., Lopes, Luísa Vaqueiro, Herrera, Federico, Giorgini, Flaviano, Outeiro, Tiago Fleming
Publicado 2016

Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane

por Swaih, Aisha M., Breda, Carlo, Sathyasaikumar, Korrapati V., Allcock, Natalie, Collier, Mary E. W., Mason, Robert P., Feasby, Adam, Herrera, Federico, Outeiro, Tiago F., Schwarcz, Robert, Repici, Mariaelena, Giorgini, Flaviano
Publicado 2022

Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability

por Robinson, Susan W., Bourgognon, Julie-Myrtille, Spiers, Jereme G., Breda, Carlo, Campesan, Susanna, Butcher, Adrian, Mallucci, Giovanna R., Dinsdale, David, Morone, Nobuhiro, Mistry, Raj, Smith, Tim M., Guerra-Martin, Maria, Challiss, R. A. John, Giorgini, Flaviano, Steinert, Joern R.
Publicado 2018

A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites

por Zhang, Shaowei, Sakuma, Michiyo, Deora, Girdhar S., Levy, Colin W., Klausing, Alex, Breda, Carlo, Read, Kevin D., Edlin, Chris D., Ross, Benjamin P., Wright Muelas, Marina, Day, Philip J., O’Hagan, Stephen, Kell, Douglas B., Schwarcz, Robert, Leys, David, Heyes, Derren J., Giorgini, Flaviano, Scrutton, Nigel S.
Publicado 2019