Bacterial β-Glucosidase Reveals the Structural and Functional Basis of Genetic Defects in Human Glucocerebrosidase 2 (GBA2)

por Charoenwattanasatien, Ratana, Pengthaisong, Salila, Breen, Imogen, Mutoh, Risa, Sansenya, Sompong, Hua, Yanling, Tankrathok, Anupong, Wu, Liang, Songsiriritthigul, Chomphunuch, Tanaka, Hideaki, Williams, Spencer J., Davies, Gideon J., Kurisu, Genji, Cairns, James R. Ketudat
Publicado 2016

Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents

por Rowland, Rhianna J., Chen, Yurong, Breen, Imogen, Wu, Liang, Offen, Wendy A., Beenakker, Thomas J., Su, Qin, van den Nieuwendijk, Adrianus M. C. H., Aerts, Johannes M. F. G., Artola, Marta, Overkleeft, Herman S., Davies, Gideon J.
Publicado 2021

1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor

por Artola, Marta, Wu, Liang, Ferraz, Maria J., Kuo, Chi-Lin, Raich, Lluís, Breen, Imogen Z., Offen, Wendy A., Codée, Jeroen D. C., van der Marel, Gijsbert A., Rovira, Carme, Aerts, Johannes M. F. G., Davies, Gideon J., Overkleeft, Herman S.
Publicado 2017

A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase

por Lahav, Daniël, Liu, Bing, van den Berg, Richard J. B. H. N., van den Nieuwendijk, Adrianus M. C. H., Wennekes, Tom, Ghisaidoobe, Amar T., Breen, Imogen, Ferraz, Maria J., Kuo, Chi-Lin, Wu, Liang, Geurink, Paul P., Ovaa, Huib, van der Marel, Gijsbert A., van der Stelt, Mario, Boot, Rolf G., Davies, Gideon J., Aerts, Johannes M. F. G., Overkleeft, Herman S.
Publicado 2017