EPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data

por Teschendorff, Andrew E., Zhu, Tianyu, Breeze, Charles E., Beck, Stephan
Publicado 2020

A comparison of reference-based algorithms for correcting cell-type heterogeneity in Epigenome-Wide Association Studies

por Teschendorff, Andrew E., Breeze, Charles E., Zheng, Shijie C., Beck, Stephan
Publicado 2017

Identification of differentially methylated cell-types in Epigenome-Wide Association Studies

por Zheng, Shijie C, Breeze, Charles E., Beck, Stephan, Teschendorff, Andrew E.
Publicado 2018

Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancer

por Chen, Yuting, Breeze, Charles E., Zhen, Shao, Beck, Stephan, Teschendorff, Andrew E.
Publicado 2016

Where next for the reproducibility agenda in computational biology?

por Lewis, Joanna, Breeze, Charles E., Charlesworth, Jane, Maclaren, Oliver J., Cooper, Jonathan
Publicado 2016

Diversity in EWAS: current state, challenges, and solutions

por Breeze, Charles E., Wong, Jason Y. Y., Beck, Stephan, Berndt, Sonja I., Franceschini, Nora
Publicado 2022

A pan-tissue DNA methylation atlas enables in silico decomposition of human tissue methylomes at cell-type resolution

por Zhu, Tianyu, Liu, Jacklyn, Beck, Stephan, Pan, Sun, Capper, David, Lechner, Matt, Thirlwell, Chrissie, Breeze, Charles E., Teschendorff, Andrew E.
Publicado 2022

EpiDISH web server: Epigenetic Dissection of Intra-Sample-Heterogeneity with online GUI

por Zheng, Shijie C, Breeze, Charles E, Beck, Stephan, Dong, Danyue, Zhu, Tianyu, Ma, Liangxiao, Ye, Wei, Zhang, Guoqing, Teschendorff, Andrew E
Publicado 2020

Epigenetic clock and methylation studies in the rhesus macaque

por Horvath, Steve, Zoller, Joseph A., Haghani, Amin, Jasinska, Anna J., Raj, Ken, Breeze, Charles E., Ernst, Jason, Vaughan, Kelli L., Mattison, Julie A.
Publicado 2021

HGF-rs12536657 and Ocular Biometric Parameters in Hyperopic Children, Emmetropic Adolescents, and Young Adults: A Multicenter Quantitative Trait Study

por Barrio-Barrio, Jesús, Bonet-Farriol, Elvira, Galdós, Marta, Noval, Susana, Pueyo, Victoria, Breeze, Charles E., Santos, Jose Luis, Alfonso-Bartolozzi, Belén, Recalde, Sergio, Patiño-García, Ana
Publicado 2019

eFORGE v2.0: updated analysis of cell type-specific signal in epigenomic data

por Breeze, Charles E, Reynolds, Alex P, van Dongen, Jenny, Dunham, Ian, Lazar, John, Neph, Shane, Vierstra, Jeff, Bourque, Guillaume, Teschendorff, Andrew E, Stamatoyannopoulos, John A, Beck, Stephan
Publicado 2019

Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations

por Breeze, Charles E., Haugen, Eric, Reynolds, Alex, Teschendorff, Andrew, van Dongen, Jenny, Lan, Qing, Rothman, Nathaniel, Bourque, Guillaume, Dunham, Ian, Beck, Stephan, Stamatoyannopoulos, John, Franceschini, Nora, Berndt, Sonja I.
Publicado 2022

Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution

por Bartlett, Thomas E., Chindera, Kantaraja, McDermott, Jacqueline, Breeze, Charles E., Cooke, William R., Jones, Allison, Reisel, Daniel, Karegodar, Smita T., Arora, Rupali, Beck, Stephan, Menon, Usha, Dubeau, Louis, Widschwendter, Martin
Publicado 2016

Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cells

por Ringh, Mikael V., Hagemann-Jensen, Michael, Needhamsen, Maria, Kular, Lara, Breeze, Charles E., Sjöholm, Louise K., Slavec, Lara, Kullberg, Susanna, Wahlström, Jan, Grunewald, Johan, Brynedal, Boel, Liu, Yun, Almgren, Malin, Jagodic, Maja, Öckinger, Johan, Ekström, Tomas J.
Publicado 2019

Genome-wide analysis of DNA methylation in buccal cells: a study of monozygotic twins and mQTLs

por van Dongen, Jenny, Ehli, Erik A., Jansen, Rick, van Beijsterveldt, Catharina E. M., Willemsen, Gonneke, Hottenga, Jouke J., Kallsen, Noah A., Peyton, Shanna A., Breeze, Charles E., Kluft, Cornelis, Heijmans, Bastiaan T., Bartels, Meike, Davies, Gareth E., Boomsma, Dorret I.
Publicado 2018

A mammalian methylation array for profiling methylation levels at conserved sequences

por Arneson, Adriana, Haghani, Amin, Thompson, Michael J., Pellegrini, Matteo, Kwon, Soo Bin, Vu, Ha, Maciejewski, Emily, Yao, Mingjia, Li, Caesar Z., Lu, Ake T., Morselli, Marco, Rubbi, Liudmilla, Barnes, Bret, Hansen, Kasper D., Zhou, Wanding, Breeze, Charles E., Ernst, Jason, Horvath, Steve
Publicado 2022

Genetic and environmental influences interact with age and sex in shaping the human methylome

por van Dongen, Jenny, Nivard, Michel G., Willemsen, Gonneke, Hottenga, Jouke-Jan, Helmer, Quinta, Dolan, Conor V., Ehli, Erik A., Davies, Gareth E., van Iterson, Maarten, Breeze, Charles E., Beck, Stephan, Suchiman, H. Eka, Jansen, Rick, van Meurs, Joyce B., Heijmans, Bastiaan T., Slagboom, P. Eline, Boomsma, Dorret I.
Publicado 2016

Potentially causal associations between placental DNA methylation and schizophrenia and other neuropsychiatric disorders

por Cilleros-Portet, Ariadna, Lesseur, Corina, Marí, Sergi, Cosin-Tomas, Marta, Lozano, Manuel, Irizar, Amaia, Burt, Amber, García-Santisteban, Iraia, Martín, Diego Garrido, Escaramís, Geòrgia, Hernangomez-Laderas, Alba, Soler-Blasco, Raquel, Breeze, Charles E., Gonzalez-Garcia, Bárbara P., Santa-Marina, Loreto, Chen, Jia, Llop, Sabrina, Fernández, Mariana F., Vrijhed, Martine, Ibarluzea, Jesús, Guxens, Mònica, Marsit, Carmen, Bustamante, Mariona, Bilbao, Jose Ramon, Fernandez-Jimenez, Nora
Publicado 2023

eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data

por Breeze, Charles E., Paul, Dirk S., van Dongen, Jenny, Butcher, Lee M., Ambrose, John C., Barrett, James E., Lowe, Robert, Rakyan, Vardhman K., Iotchkova, Valentina, Frontini, Mattia, Downes, Kate, Ouwehand, Willem H., Laperle, Jonathan, Jacques, Pierre-Étienne, Bourque, Guillaume, Bergmann, Anke K., Siebert, Reiner, Vellenga, Edo, Saeed, Sadia, Matarese, Filomena, Martens, Joost H.A., Stunnenberg, Hendrik G., Teschendorff, Andrew E., Herrero, Javier, Birney, Ewan, Dunham, Ian, Beck, Stephan
Publicado 2016

DNA methylation predicts age and provides insight into exceptional longevity of bats

por Wilkinson, Gerald S., Adams, Danielle M., Haghani, Amin, Lu, Ake T., Zoller, Joseph, Breeze, Charles E., Arnold, Bryan D., Ball, Hope C., Carter, Gerald G., Cooper, Lisa Noelle, Dechmann, Dina K. N., Devanna, Paolo, Fasel, Nicolas J., Galazyuk, Alexander V., Günther, Linus, Hurme, Edward, Jones, Gareth, Knörnschild, Mirjam, Lattenkamp, Ella Z., Li, Caesar Z., Mayer, Frieder, Reinhardt, Josephine A., Medellin, Rodrigo A., Nagy, Martina, Pope, Brian, Power, Megan L., Ransome, Roger D., Teeling, Emma C., Vernes, Sonja C., Zamora-Mejías, Daniel, Zhang, Joshua, Faure, Paul A., Greville, Lucas J., Herrera M., L. Gerardo, Flores-Martínez, José J., Horvath, Steve
Publicado 2021