Improved B cell development in humanized NOD‐scid IL2Rγ(null) mice transgenically expressing human stem cell factor, granulocyte‐macrophage colony‐stimulating factor and interleuki...

por Jangalwe, Sonal, Shultz, Leonard D., Mathew, Anuja, Brehm, Michael A.
Publicado 2016

Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice

por Lee, Jinhee, Brehm, Michael A, Greiner, Dale, Shultz, Leonard D, Kornfeld, Hardy
Publicado 2013

Generation of improved humanized mouse models for human infectious diseases

por Brehm, Michael A., Wiles, Michael V., Greiner, Dale L., Shultz, Leonard D.
Publicado 2014

Maturation-Dependent Licensing of Naive T Cells for Rapid TNF Production

por Priyadharshini, Bhavana, Welsh, Raymond M., Greiner, Dale L., Gerstein, Rachel M., Brehm, Michael A.
Publicado 2010

Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells

por Leite, Nayara C., Sintov, Elad, Meissner, Torsten B., Brehm, Michael A., Greiner, Dale L., Harlan, David M., Melton, Douglas A.
Publicado 2020

Enhanced development of functional human NK cells in NOD‐ scid‐IL2rg(null) mice expressing human IL15

por Aryee, Ken‐Edwin, Burzenski, Lisa M., Yao, Li‐Chin, Keck, James G., Greiner, Dale L., Shultz, Leonard D., Brehm, Michael A.
Publicado 2022

CD8 memory T cells: cross-reactivity and heterologous immunity

por Selin, Liisa K., Cornberg, Markus, Brehm, Michael A., Kim, Sung-Kwon, Calcagno, Claudia, Ghersi, Dario, Puzone, Roberto, Celada, Franco, Welsh, Raymond M.
Publicado 2004

Salicylate Prevents Virus-Induced Type 1 Diabetes in the BBDR Rat

por Yang, Chaoxing, Jurczyk, Agata, diIorio, Philip, Norowski, Elaine, Brehm, Michael A., Grant, Christian W., Guberski, Dennis L., Greiner, Dale L., Bortell, Rita
Publicado 2013

Viral Infection of Engrafted Human Islets Leads to Diabetes

por Gallagher, Glen R., Brehm, Michael A., Finberg, Robert W., Barton, Bruce A., Shultz, Leonard D., Greiner, Dale L., Bortell, Rita, Wang, Jennifer P.
Publicado 2015

Idd Loci Synergize to Prolong Islet Allograft Survival Induced by Costimulation Blockade in NOD Mice

por Mangada, Julie, Pearson, Todd, Brehm, Michael A., Wicker, Linda S., Peterson, Laurence B., Shultz, Leonard D., Serreze, David V., Rossini, Aldo A., Greiner, Dale L.
Publicado 2009

Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV‐1 pathogenesis

por Wang, Yetao, Lifshitz, Lawrence, Silverstein, Noah J, Mintzer, Esther, Luk, Kevin, StLouis, Pamela, Brehm, Michael A, Wolfe, Scot A, Deeks, Steven G, Luban, Jeremy
Publicado 2023

IRF4 Regulates the Ratio of T-Bet to Eomesodermin in CD8(+) T Cells Responding to Persistent LCMV Infection

por Nayar, Ribhu, Schutten, Elizabeth, Jangalwe, Sonal, Durost, Philip A., Kenney, Laurie L., Conley, James M., Daniels, Keith, Brehm, Michael A., Welsh, Raymond M., Berg, Leslie J.
Publicado 2015

Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice

por Schleifman, Erica B, McNeer, Nicole Ali, Jackson, Andrew, Yamtich, Jennifer, Brehm, Michael A, Shultz, Leonard D, Greiner, Dale L, Kumar, Priti, Saltzman, W Mark, Glazer, Peter M
Publicado 2013

Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of α-1 Antitrypsin Deficiency

por Borel, Florie, Tang, Qiushi, Gernoux, Gwladys, Greer, Cynthia, Wang, Ziqiong, Barzel, Adi, Kay, Mark A., Shultz, Leonard D., Greiner, Dale L., Flotte, Terence R., Brehm, Michael A., Mueller, Christian
Publicado 2017

Modeling human T1D-associated autoimmune processes

por Khosravi-Maharlooei, Mohsen, Madley, Rachel, Borsotti, Chiara, Ferreira, Leonardo M.R., Sharp, Robert C., Brehm, Michael A., Greiner, Dale L., Parent, Audrey V., Anderson, Mark S., Sykes, Megan, Creusot, Remi J.
Publicado 2021

Discovery of an agonistic Siglec-6 antibody that inhibits and reduces human mast cells

por Schanin, Julia, Korver, Wouter, Brock, Emily C., Leung, John, Benet, Zachary, Luu, Thuy, Chang, Katherine, Xu, Alan, De Freitas, Naomi, Luehrsen, Kenneth, Brehm, Michael A., Wong, Alan, Youngblood, Bradford A.
Publicado 2022

Human ‘brite / beige’ adipocytes develop from capillary networks and their implantation improves metabolic homeostasis in mice

por Min, So Yun, Kady, Jamie, Nam, Minwoo, Rojas-Rodriguez, Raziel, Berkenwald, Aaron, Kim, Jong Hun, Noh, Hye-Lim, Kim, Jason K., Cooper, Marcus P., Fitzgibbons, Timothy, Brehm, Michael A., Corvera, Silvia
Publicado 2016

Human Immune System Development and Rejection of Human Islet Allografts in Spontaneously Diabetic NOD-Rag1(null) IL2rγ(null) Ins2(Akita) Mice

por Brehm, Michael A., Bortell, Rita, diIorio, Philip, Leif, Jean, Laning, Joseph, Cuthbert, Amy, Yang, Chaoxing, Herlihy, Mary, Burzenski, Lisa, Gott, Bruce, Foreman, Oded, Powers, Alvin C., Greiner, Dale L., Shultz, Leonard D.
Publicado 2010

CHOP Mediates Endoplasmic Reticulum Stress-Induced Apoptosis in Gimap5-Deficient T Cells

por Pino, Steven C., O'Sullivan-Murphy, Bryan, Lidstone, Erich A., Yang, Chaoxing, Lipson, Kathryn L., Jurczyk, Agata, diIorio, Philip, Brehm, Michael A., Mordes, John P., Greiner, Dale L., Rossini, Aldo A., Bortell, Rita
Publicado 2009

Proteomic and Transcriptional Profiles of Human Stem Cell-Derived β Cells Following Enteroviral Challenge

por Nyalwidhe, Julius O., Jurczyk, Agata, Satish, Basanthi, Redick, Sambra, Qaisar, Natasha, Trombly, Melanie I., Vangala, Pranitha, Racicot, Riccardo, Bortell, Rita, Harlan, David M., Greiner, Dale L., Brehm, Michael A., Nadler, Jerry L., Wang, Jennifer P.
Publicado 2020