pFTAA: a high affinity oligothiophene probe that detects filamentous tau in vivo and in cultured neurons

por Brelstaff, Jack, Spillantini, Maria Grazia, Tolkovsky, Aviva M.
Publicado 2015

Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia

por Brelstaff, Jack, Tolkovsky, Aviva M., Ghetti, Bernardino, Goedert, Michel, Spillantini, Maria Grazia
Publicado 2018

Microglia become hypofunctional and release metalloproteases and tau seeds when phagocytosing live neurons with P301S tau aggregates

por Brelstaff, Jack H., Mason, Matthew, Katsinelos, Taxiarchis, McEwan, William A., Ghetti, Bernardino, Tolkovsky, Aviva M., Spillantini, Maria Grazia
Publicado 2021

The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice

por Brelstaff, Jack, Ossola, Bernardino, Neher, Jonas J., Klingstedt, Therése, Nilsson, K. Peter R., Goedert, Michel, Spillantini, Maria Grazia, Tolkovsky, Aviva M.
Publicado 2015

The microglial P2Y(6) receptor mediates neuronal loss and memory deficits in neurodegeneration

por Puigdellívol, Mar, Milde, Stefan, Vilalta, Anna, Cockram, Tom O.J., Allendorf, David H., Lee, Jeffrey Y., Dundee, Jacob M., Pampuščenko, Katryna, Borutaite, Vilmante, Nuthall, Hugh N., Brelstaff, Jack H., Spillantini, Maria Grazia, Brown, Guy C.
Publicado 2021

Characterization of full-length p53 aggregates and their kinetics of formation

por Julian, Linda, Sang, Jason C., Wu, Yunzhao, Meisl, Georg, Brelstaff, Jack H., Miller, Alyssa, Cheetham, Matthew R., Vendruscolo, Michele, Knowles, Tuomas P.J., Ruggeri, Francesco Simone, Bryant, Clare, Ros, Susana, Brindle, Kevin M., Klenerman, David
Publicado 2022

Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination

por Fricker, Florence R., Antunes-Martins, Ana, Galino, Jorge, Paramsothy, Remi, La Russa, Federica, Perkins, James, Goldberg, Rebecca, Brelstaff, Jack, Zhu, Ning, McMahon, Stephen B., Orengo, Christine, Garratt, Alistair N., Birchmeier, Carmen, Bennett, David L. H.
Publicado 2013