Editorial: The molecular mechanisms of epilepsy and potential therapeutics

por Engel, Tobias, Brennan, Gary P., Soreq, Hermona
Publicado 2022

Regulatory Mechanisms of the RNA Modification m(6)A and Significance in Brain Function in Health and Disease

por Mathoux, Justine, Henshall, David C., Brennan, Gary P.
Publicado 2021

MicroRNA Profiling Shows a Time-Dependent Regulation within the First 2 Months Post-Birth and after Mild Neonatal Hypoxia in the Hippocampus from Mice

por Leavy, Aisling, Brennan, Gary P., Jimenez-Mateos, Eva M.
Publicado 2022

CHD2-Related CNS Pathologies

por Wilson, Marc-Michel, Henshall, David C., Byrne, Susan M., Brennan, Gary P.
Publicado 2021

Spared CA1 pyramidal neuron function and hippocampal performance following antisense knockdown of microRNA‐134

por Morris, Gareth, Brennan, Gary P., Reschke, Cristina R., Henshall, David C., Schorge, Stephanie
Publicado 2018

Multiple Disruptions of Glial-Neuronal Networks in Epileptogenesis That Follows Prolonged Febrile Seizures

por Brennan, Gary P., Garcia-Curran, Megan M., Patterson, Katelin P., Luo, Renhao, Baram, Tallie Z.
Publicado 2021

Transgenic Overexpression of 14-3-3 Zeta Protects Hippocampus against Endoplasmic Reticulum Stress and Status Epilepticus In Vivo

por Brennan, Gary P., Jimenez-Mateos, Eva M., McKiernan, Ross C., Engel, Tobias, Tzivion, Guri, Henshall, David C.
Publicado 2013

The transcription factor NRSF contributes to epileptogenesis by selective repression of a subset of target genes

por McClelland, Shawn, Brennan, Gary P, Dubé, Celine, Rajpara, Seeta, Iyer, Shruti, Richichi, Cristina, Bernard, Christophe, Baram, Tallie Z
Publicado 2014

The Role of Sirt1 in Epileptogenesis

por Hall, Alicia M., Brennan, Gary P., Nguyen, Tiffany M., Singh-Taylor, Akanksha, Mun, Hyun-Seung, Sargious, Mary J., Baram, Tallie Z.
Publicado 2017

Rapid, Coordinate Inflammatory Responses after Experimental Febrile Status Epilepticus: Implications for Epileptogenesis

por Patterson, Katelin P., Brennan, Gary P., Curran, Megan, Kinney-Lang, Eli, Dubé, Celine, Rashid, Faisal, Ly, Catherine, Obenaus, Andre, Baram, Tallie Z.
Publicado 2015

RNA-sequencing analysis of umbilical cord plasma microRNAs from healthy newborns

por Brennan, Gary P., Vitsios, Dimitrios M., Casey, Sophie, Looney, Ann-Marie, Hallberg, Boubou, Henshall, David C., Boylan, Geraldine B., Murray, Deirdre M., Mooney, Catherine
Publicado 2018

Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus

por Batool, Aasia, Hill, Thomas D. M., Nguyen, Ngoc T., Langa, Elena, Diviney, Mairéad, Mooney, Catherine, Brennan, Gary P., Connolly, Niamh M. C., Sanz-Rodriguez, Amaya, Cavanagh, Brenton L., Henshall, David C.
Publicado 2020

Spatiotemporal progression of ubiquitin-proteasome system inhibition after status epilepticus suggests protective adaptation against hippocampal injury

por Engel, Tobias, Martinez-Villarreal, Jaime, Henke, Christine, Jimenez-Mateos, Eva M., Sanz-Rodriguez, Amaya, Alves, Mariana, Hernandez-Santana, Yasmina, Brennan, Gary P., Kenny, Aidan, Campbell, Aoife, Lucas, Jose J., Henshall, David C.
Publicado 2017

Genetic deletion of microRNA-22 blunts the inflammatory transcriptional response to status epilepticus and exacerbates epilepsy in mice

por Almeida Silva, Luiz F., Reschke, Cristina R., Nguyen, Ngoc T., Langa, Elena, Sanz-Rodriguez, Amaya, Gerbatin, Rogerio R., Temp, Fernanda R., de Freitas, Mayara L., Conroy, Ronan M., Brennan, Gary P., Engel, Tobias, Henshall, David C.
Publicado 2020

Reduced Mature MicroRNA Levels in Association with Dicer Loss in Human Temporal Lobe Epilepsy with Hippocampal Sclerosis

por McKiernan, Ross C., Jimenez-Mateos, Eva M., Bray, Isabella, Engel, Tobias, Brennan, Gary P., Sano, Takanori, Michalak, Zuzanna, Moran, Catherine, Delanty, Norman, Farrell, Michael, O’Brien, Donncha, Meller, Robert, Simon, Roger P., Stallings, Raymond L., Henshall, David C.
Publicado 2012

Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy

por Raoof, Rana, Bauer, Sebastian, El Naggar, Hany, Connolly, Niamh M.C., Brennan, Gary P., Brindley, Elizabeth, Hill, Thomas, McArdle, Hazel, Spain, Elaine, Forster, Robert J., Prehn, Jochen H.M., Hamer, Hajo, Delanty, Norman, Rosenow, Felix, Mooney, Catherine, Henshall, David C.
Publicado 2018

Temporally Altered miRNA Expression in a Piglet Model of Hypoxic Ischemic Brain Injury

por Casey, Sophie, Goasdoue, Kate, Miller, Stephanie M., Brennan, Gary P., Cowin, Gary, O’Mahony, Adam G., Burke, Christopher, Hallberg, Boubou, Boylan, Geraldine B., Sullivan, Aideen M., Henshall, David C., O’Keeffe, Gerard W., Mooney, Catherine, Bjorkman, Tracey, Murray, Deirdre M.
Publicado 2020

Brain cell-specific origin of circulating microRNA biomarkers in experimental temporal lobe epilepsy

por Brindley, Elizabeth, Heiland, Mona, Mooney, Catherine, Diviney, Mairead, Mamad, Omar, Hill, Thomas D. M., Yan, Yan, Venø, Morten T., Reschke, Cristina R., Batool, Aasia, Langa, Elena, Sanz-Rodriguez, Amaya, Heller, Janosch P., Morris, Gareth, Conboy, Karen, Kjems, Jørgen, Brennan, Gary P., Henshall, David C.
Publicado 2023

Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy

por Reschke, Cristina R., Silva, Luiz F.A., Vangoor, Vamshidhar R., Rosso, Massimo, David, Bastian, Cavanagh, Brenton L., Connolly, Niamh M.C., Brennan, Gary P., Sanz-Rodriguez, Amaya, Mooney, Catherine, Batool, Aasia, Greene, Chris, Brennan, Marian, Conroy, Ronan M., Rüber, Theodor, Prehn, Jochen H.M., Campbell, Matthew, Pasterkamp, R. Jeroen, Henshall, David C.
Publicado 2021

A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy

por Venø, Morten T., Reschke, Cristina R., Morris, Gareth, Connolly, Niamh M. C., Su, Junyi, Yan, Yan, Engel, Tobias, Jimenez-Mateos, Eva M., Harder, Lea M., Pultz, Dennis, Haunsberger, Stefan J., Pal, Ajay, Heller, Janosch P., Campbell, Aoife, Langa, Elena, Brennan, Gary P., Conboy, Karen, Richardson, Amy, Norwood, Braxton A., Costard, Lara S., Neubert, Valentin, Del Gallo, Federico, Salvetti, Beatrice, Vangoor, Vamshidhar R., Sanz-Rodriguez, Amaya, Muilu, Juha, Fabene, Paolo F., Pasterkamp, R. Jeroen, Prehn, Jochen H. M., Schorge, Stephanie, Andersen, Jens S., Rosenow, Felix, Bauer, Sebastian, Kjems, Jørgen, Henshall, David C.
Publicado 2020