Spotlight on naldemedine in the treatment of opioid-induced constipation in adult patients with chronic noncancer pain: design, development, and place in therapy

por Stern, Emily K, Brenner, Darren M
Publicado 2018

Gut Microbiota-Based Therapies for Irritable Bowel Syndrome

por Stern, Emily K, Brenner, Darren M
Publicado 2018

Antispasmodics for Chronic Abdominal Pain: Analysis of North American Treatment Options

por Brenner, Darren M., Lacy, Brian E.
Publicado 2021

Differential Diagnosis of Chronic Diarrhea: An Algorithm to Distinguish Irritable Bowel Syndrome With Diarrhea From Other Organic Gastrointestinal Diseases, With Special Focus on E...

por Brenner, Darren M., Domínguez-Muñoz, J. Enrique
Publicado 2023

Efficacy and Safety of Over-the-Counter Therapies for Chronic Constipation: An Updated Systematic Review

por Rao, Satish S.C., Brenner, Darren M.
Publicado 2021

Evidence-based treatment recommendations for OTC management of chronic constipation

por Rao, Satish S.C., Brenner, Darren M.
Publicado 2022

Improved work productivity and health-related quality of life in patients with irritable bowel syndrome with diarrhea receiving eluxadoline following inadequate response to loperam...

por Brenner, Darren M, Sayuk, Gregory S, Abel, Jessica L, Burslem, Kate
Publicado 2021

A Randomized, Multicenter, Prospective, Crossover, Open-Label Study of Factors Associated With Patient Preferences for Naloxegol or PEG 3350 for Opioid-Induced Constipation

por Brenner, Darren M., Hu, Yiqun, Datto, Catherine, Creanga, Dana, Camilleri, Michael
Publicado 2019

Efficacy and Safety of Neostigmine and Decompressive Colonoscopy for Acute Colonic Pseudo-Obstruction: A Single-Center Analysis

por Liu, Joy J., Venkatesh, Vishnu, Gao, Jing, Adler, Emerald, Brenner, Darren M.
Publicado 2021

The influence of brain metastases on the central nervous system effects of methylnaltrexone: a post hoc analysis of 3 randomized, double-blind studies

por Brenner, Darren M., Slatkin, Neal E., Stambler, Nancy, Israel, Robert J., Coluzzi, Paul H.
Publicado 2021

Tegaserod for Irritable Bowel Syndrome With Constipation in Women Younger Than 65 Years Without Cardiovascular Disease: Pooled Analyses of 4 Controlled Trials

por Shah, Eric D., Lacy, Brian E., Chey, William D., Chang, Lin, Brenner, Darren M.
Publicado 2021

Validity of the ≥50% Response Threshold in Treatment With NASHA/Dx Injection Therapy for Fecal Incontinence

por Sanchez, Jaime E, Brenner, Darren M, Franklin, Howard, Yu, Jing, Barrett, Andrew C, Paterson, Craig
Publicado 2015

Plecanatide Improves Symptoms of Irritable Bowel Syndrome with Constipation: Results of an Integrated Efficacy and Safety Analysis of Two Phase 3 Trials

por Brenner, Darren M, Dorn, Spencer D, Fogel, Ronald P, Christie, Jennifer, Laitman, Adam P, Rosenberg, Jonathan
Publicado 2023

Analysis of opioid-mediated analgesia in Phase III studies of methylnaltrexone for opioid-induced constipation in patients with chronic noncancer pain

por Webster, Lynn R, Brenner, Darren M, Barrett, Andrew C, Paterson, Craig, Bortey, Enoch, Forbes, William P
Publicado 2015

Efficacy and Safety of Eluxadoline in Patients With Irritable Bowel Syndrome With Diarrhea Who Report Inadequate Symptom Control With Loperamide: RELIEF Phase 4 Study

por Brenner, Darren M., Sayuk, Gregory S., Gutman, Catherine R., Jo, Esther, Elmes, Steven J. R., Liu, Louis W. C., Cash, Brooks D.
Publicado 2019

Linaclotide Reduced Response Time for Irritable Bowel Syndrome With Constipation Symptoms: Analysis of 4 Randomized Controlled Trials

por Brenner, Darren M., Lacy, Brian E., Ford, Alexander C., Bartolini, Wilmin, Wu, James, Shea, Elizabeth P., Bochenek, Wieslaw, Boinpally, Ramesh, Almansa, Cristina
Publicado 2023

Efficacy and Safety of Naloxegol in Patients with Chronic Non-Cancer Pain Who Experience Opioid-Induced Constipation: A Pooled Analysis of Two Global, Randomized Controlled Studies

por Chey, William D, Brenner, Darren M, Cash, Brooks D, Hale, Martin, Adler, Jeremy, Jamindar, Mansi S, Rockett, Carol B, Almenoff, June S, Bortey, Enoch, Gudin, Jeffrey
Publicado 2023

Efficacy and safety of linaclotide for opioid-induced constipation in patients with chronic noncancer pain syndromes from a phase 2 randomized study

por Brenner, Darren M., Argoff, Charles E., Fox, Susan M., Bochenek, Wieslaw, D'Astoli, Patricia, Blakesley, Rick E., Reasner, David S., O'Dea, Christopher R., Cash, Brooks D.
Publicado 2020