FG-3019, a Human Monoclonal Antibody Recognizing Connective Tissue Growth Factor, is Subject to Target-Mediated Drug Disposition

por Brenner, Mitchell C., Krzyzanski, Wojciech, Chou, James Z., Signore, Pierre E., Fung, Cyra K., Guzman, David, Li, Dongxia, Zhang, Weihua, Olsen, David R., Nguyen, Viet-Tam L., Koo, Carolyn W., Sternlicht, Mark D., Lipson, Kenneth E.
Publicado 2016

Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase

por Zheng, Xingnan, Zhai, Bo, Koivunen, Peppi, Shin, Sandra J., Lu, Gang, Liu, Jiayun, Geisen, Christoph, Chakraborty, Abhishek A., Moslehi, Javid J., Smalley, David M., Wei, Xin, Chen, Xian, Chen, Zhengming, Beres, Justine M., Zhang, Jing, Tsao, Jen Lan, Brenner, Mitchell C., Zhang, Yuqing, Fan, Cheng, DePinho, Ronald A., Paik, Jihye, Gygi, Steven P., Kaelin, William G., Zhang, Qing
Publicado 2014