Current Strategies to Enhance Anti-Tumour Immunity

por Cook, Katherine W., Durrant, Lindy G., Brentville, Victoria A.
Publicado 2018

High Avidity Cytotoxic T Lymphocytes Can Be Selected into the Memory Pool but They Are Exquisitely Sensitive to Functional Impairment

por Brentville, Victoria A., Metheringham, Rachael L., Gunn, Barbara, Durrant, Lindy G.
Publicado 2012

Cancer Vaccines, Adjuvants, and Delivery Systems

por Paston, Samantha J., Brentville, Victoria A., Symonds, Peter, Durrant, Lindy G.
Publicado 2021

Citrullinated Epitopes Identified on Tumour MHC Class II by Peptide Elution Stimulate Both Regulatory and Th1 Responses and Require Careful Selection for Optimal Anti-Tumour Respon...

por Symonds, Peter, Marcu, Ana, Cook, Katherine W., Metheringham, Rachael L., Durrant, Lindy G., Brentville, Victoria A.
Publicado 2021

SCIB1, a huIgG1 antibody DNA vaccination, combined with PD-1 blockade induced efficient therapy of poorly immunogenic tumors

por Xue, Wei, Brentville, Victoria A., Symonds, Peter, Cook, Katherine W., Yagita, Hideo, Metheringham, Rachael L., Durrant, Lindy G.
Publicado 2016

SCIB2, an antibody DNA vaccine encoding NY-ESO-1 epitopes, induces potent antitumor immunity which is further enhanced by checkpoint blockade

por Xue, Wei, Metheringham, Rachael L., Brentville, Victoria A., Gunn, Barbara, Symonds, Peter, Yagita, Hideo, Ramage, Judith M., Durrant, Lindy G.
Publicado 2016

PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy

por Choudhury, Ruhul H, Symonds, Peter, Paston, Samantha J, Daniels, Ian, Cook, Katherine W, Gijon, Mohamed, Metheringham, Rachael L, Brentville, Victoria A, Durrant, Lindy G
Publicado 2022

Vaccination with post-translational modified, homocitrullinated peptides induces CD8 T-cell responses that mediate antitumor immunity

por Shah, Sabaria, Cook, Katherine W, Symonds, Peter, Weißer, Juliane, Skinner, Anne, Al Omari, Abdullah, Paston, Samantha J, Pike, Ian, Durrant, Lindy G, Brentville, Victoria A
Publicado 2023

T cell repertoire to citrullinated self-peptides in healthy humans is not confined to the HLA-DR SE alleles; Targeting of citrullinated self-peptides presented by HLA-DP4 for tumou...

por Brentville, Victoria A, Symonds, Peter, Cook, Katherine W, Daniels, Ian, Pitt, Tracy, Gijon, Mohamed, Vaghela, Poonam, Xue, Wei, Shah, Sabaria, Metheringham, Rachael L, Durrant, Lindy G
Publicado 2019

Combination vaccine based on citrullinated vimentin and enolase peptides induces potent CD4-mediated anti-tumor responses

por Brentville, Victoria A, Metheringham, Rachael L, Daniels, Ian, Atabani, Suha, Symonds, Peter, Cook, Katherine W, Vankemmelbeke, Mireille, Choudhury, Ruhul, Vaghela, Poonam, Gijon, Mohamed, Meiners, Ghislaine, Krebber, Willem-Jan, Melief, Cornelis J M, Durrant, Lindy G
Publicado 2020

Homocitrullination of lysine residues mediated by myeloid-derived suppressor cells in the tumor environment is a target for cancer immunotherapy

por Cook, Katherine W, Xue, Wei, Symonds, Peter, Daniels, Ian, Gijon, Mohamed, Boocock, David, Coveney, Clare, Miles, Amanda K, Shah, Sabaria, Atabani, Suha, Choudhury, Ruhul H, Vaghela, Poonam, Weston, Daisy, Metheringham, Rachael L, Brentville, Victoria A, Durrant, Lindy G
Publicado 2021

Targeting gp100 and TRP-2 with a DNA vaccine: Incorporating T cell epitopes with a human IgG1 antibody induces potent T cell responses that are associated with favourable clinical...

por Patel, Poulam M., Ottensmeier, Christian H., Mulatero, Clive, Lorigan, Paul, Plummer, Ruth, Pandha, Hardev, Elsheikh, Somaia, Hadjimichael, Efthymios, Villasanti, Naty, Adams, Sally E., Cunnell, Michelle, Metheringham, Rachael L., Brentville, Victoria A., Machado, Lee, Daniels, Ian, Gijon, Mohamed, Hannaman, Drew, Durrant, Lindy G.
Publicado 2018